Adam Carr
San Mateo,CA
Summary
Accomplished Senior Scientist with a proven track record at BigHat Biosciences and co-founder of Frugi Biotechnology Inc., specializing in cell-free protein synthesis and high-throughput screening. Demonstrated leadership in enhancing cell-free expression systems capabilities for antibody expression while reducing costs by innovative reagent manufacturing and research initiatives.
Overview
3
3
years of professional experience
Work History
Senior Scientist, Cell Free Production
BigHat Biosciences
San Mateo, CA
03.2024 - Current
- Led team of four scientists and research associates to enhance cell-free expression systems.
- Develop protocols to increase number of antibody formats our CFE platform can support for a diverse portfolio of programs.
- Enhance internal CFE reagent manufacturing workflows, boosting screening throughput.
Scientist, Cell Free Production
BigHat Biosciences
San Mateo, CA
08.2022 - 03.2024
- Reduced the costs of the CFE platform by 50x by onboarding an internal CFE reagent manufacturing pipeline.
- Increased protein yields from CFE using novel codon optimization methods and CFPS reaction protocol optimization.
VP Technology, Co-Founder
Frugi Biotechnology Inc.
Ames, IA
09.2021 - 08.2022
- Directed team of three scientists and research associates as Principal Investigator on a funded NSF SBIR Phase I project.
- Developed a manufacturing process that improved batch-to-batch consistency of extract-based CFPS reagents.
- Directed acquisition and integration of Frugi’s CFE platform by BigHat Biosciences to enhance scalability.
Education
Ph.D. - Chemical Engineering
Iowa State University
Ames, IA09-2022
Bachelor of Science - Chemical Engineering
Brigham Young University
Provo, UT06-2018
Skills
- Cell-free protein synthesis
- Cell-free reagent manufacturing
- High-throughput screening
- Polymerase Chain Reaction
- Rolling circle amplification
- Sub-cloning techniques
- Protein purification
- CE-SDS
- SEC-HPLC
- nanoDSF, SLS, DLS
- Biolayer interferometry
- Python
Timeline
Senior Scientist, Cell Free Production
BigHat Biosciences
03.2024 - Current
Scientist, Cell Free Production
BigHat Biosciences
08.2022 - 03.2024
VP Technology, Co-Founder
Frugi Biotechnology Inc.
09.2021 - 08.2022
Ph.D. - Chemical Engineering
Iowa State University
Bachelor of Science - Chemical Engineering
Brigham Young University