Albert Armoo
Maple Grove
Summary
A motivated, keen, and driven individual with more than 6 years of experience in biochemical/molecular biology-based methodologies to support development, licensing, and commercial release of various biopharmaceutical products in a cGMP/cGLP industry.. Resourceful and adaptable individual who works equally well independently and in collaboration to execute assigned experiments in a manner consistent with project goals and reports data in a clear and concise manner.
Overview
10
10
years of professional experience
Work History
Graduate Teaching and Research Assistant
South Dakota State University
08.2019 - Current
- Teaching undergraduate General and Organic Chemistry
- Executing the Professor's lesson plans and maintaining daily laboratory schedules
- Using a range of instructional and appraisal strategies, as directed by the Professor of the course, to meet individual student needs
- Assisting students with assignments and explaining difficult concepts.
QC - Senior Scientist
Envigo
06.2018 - 06.2019
- Developed and validated bioassays required for product characterization, release and stability tests
- Experience in Quality Control environment with a good understanding of applying cGMP
- Trained junior and new scientists on Aseptic techniques and safety
- Met potential clients face-2-face, conducted scientific reviews of their methods and SOPs and aided in the transfer of their assays to the Bioassay department
- Good working knowledge of data processing system and providing data for regulatory submissions
- Used a variety of laboratory instrumentation and computer systems to collect and record data such as LIMS
- Initiated and owned quality deviations, CAPAs, change controls and out of specification results within the electronic Quality Management System
- Collated and analysed analytical data to support process control and product characterisation, release, and stability tests
- Provided appropriate training for junior staff to develop their skills and the group knowledge base.
Experimental Officer II
Covance
08.2017 - 06.2018
- Reviewed all data generated for any potential OOS results and flag with QC Scientist
- Used of Biomek NXP and Biomek 3000 which are both compact liquid handlers ideal for standardise daily pipetting routines, maintain sample quality and generate repeatable, reliable results
- Responsible for the generation of a Study File for an individual study including the generation of data tables
- Ensured all assays performed are monitored for timely completion and adherence to protocol requirements under cGMP condition
- Where this is not the case, ensured the deviation procedure is followed
- Reviewed and ensured all assay study files are completed and checked before QA submission.
Senior Study Scientist
Envigo
07.2016 - 08.2017
- Analysed the relative potency of an antibody drug conjugate (ADC) by cytotoxicity to cells expressing cluster of differentiation 19 (CD19)
- Routinely performed cell-based assay to determine the biological activity of a Glucagon-Like Peptide-1 (GLP-1) on HEK293F cell line engineered to stably express the human GLP-1 receptor
- Conducted a scientific review of client methods/SOPs and made recommendations regarding the transfer and conduct of these assays into Bioassay
- Study Supervision responsibilities including direct interaction with clients via visits onsite
- Knowledge of progression of projects from development, qualification, validation to batch release and stability programs.
Study Scientist
Envigo
04.2015 - 07.2016
- Performed cell-based assays within a GMP laboratory under minimal supervision
- Responsible for culturing a wide variety of mammalian cell lines such as HEK293F, WIL2-S SF, YTS-2DL and LCL-CW4
- Understanding of quality systems (Deviation / CAPA / Change control / OOS)
- Ensure safe working practices with due regard to COSHH and HASAWA associated with the use of chemicals in the laboratory.
Laboratory Assistant
Cyprotex Discovery
05.2014 - 02.2015
- Performed cell based In-vitro toxicology assays including mitochondrial toxicity using the Glu/Gal assay, single endpoint cell viability such as MTT
- Micronucleus test using fluorescent cellular imaging, high content screening (HCS) and an ArrayScan VTI HCS reader (Thermo Scientific Cellomics)
- Responsible for culturing a variety of mammalian cell lines including CHO-K1, HepG2, KeratinoSens cell line using aseptic techniques.
Internship
Institute of Cancer Therapeutics (ICT)
12.2013 - 05.2014
- Performed MTT assay on HCT116 and SW480 cell lines to determine chemo-sensitivity of compounds manufactured by in-house
- Performed cell culture including EJ-138, HCT116 and SW480.
Education
PhD. Biochemistry -
South Dakota University
Brookings, South Dakota06.2024
MSc. Drug Toxicology and Safety Pharmacology -
University of Bradford
Bradford, United Kingdom01.2013
Bsc. (Hons) Biomedical Science -
University of Bradford
Bradford, United Kingdom01.2012
Skills
- In depth hands-on experience with tumor and immune cell culture and cryopreservation in cGMP/cGLP compliance laboratories
- Thorough knowledge of in vitro assays including Aseptic techniques, MTT Assay, Cell Matrix Adhesion Assay, Apoptosis, ELISA
- Reviewing and writing methods and SOPs
- Molecular Techniques: Western Blotting, Immunofluorescence Assay and Flow Cytometry
- Organic compound purification techniques: flash chromatography, NMR, TLC, distillation, and vacuum filtration
- Data Analysis: GraphPad Prism, Microsoft Excel
- Research Reporting
- Research Design
- Research Paper Writing
- Experimental Design
- Data Analysis
- Technical Writing
- Regulatory Compliance
- Data Collection
- Grant Writing
- Quality Assurance
- Lab Safety
- Research and Publication
- Documentation Abilities
- Documentation Skills
- Quantitative and Qualitative Analysis
- Problem-Solving
- Research Project Design
- Conducting Assays
- Teamwork and Collaboration
- Attention to Detail
- Publication Preparation
- EndNote proficiency
- Problem solving
- Critical thinking
- Scientific writing
- Team collaboration
- Literature review
- Assay Development
- Safety Processes and Procedures
- Research Methods
- Results Analysis
- Project Management
- Peer Reviews
- Research and Experiments
- Cell culture techniques
- Immunological assays
- Experimental design
- Research methodology
- Team Collaboration
- Cell Culture
- Research Coordination
- Research Planning
- Effective Multitasking
- Technical Consulting
- Strong Work Ethic
- Self-Directed and Motivated
Publications
- Susan Grabenstein, Karen N Barnard, Mathias Anim, Albert Armoo, Wendy S Weichert, Carolyn R Bertozzi, Colin R Parrish, Rachel Willand-Charnley, Deacetylated sialic acids modulates immune mediated cytotoxicity via the sialic acid-Siglec pathway, Glycobiology, 31, 10, 1279-1294, 2021
- Albert Armoo, Tanner Diemer, Abigail Donkor, Jerrod Fedorchik, Severine Van slambrouck, Rachel Willand-Charnley and Brian A. Logue, 'Methimazole, an effective scavenger of the sulfur derivative, 2-Chloro Ethyl Sulfide, ACS Bio Med Chem Au, 10.1021/acsbiomedchemau.2c00087, 2023
Timeline
Graduate Teaching and Research Assistant
South Dakota State University
08.2019 - Current
QC - Senior Scientist
Envigo
06.2018 - 06.2019
Experimental Officer II
Covance
08.2017 - 06.2018
Senior Study Scientist
Envigo
07.2016 - 08.2017
Study Scientist
Envigo
04.2015 - 07.2016
Laboratory Assistant
Cyprotex Discovery
05.2014 - 02.2015
Internship
Institute of Cancer Therapeutics (ICT)
12.2013 - 05.2014
PhD. Biochemistry -
South Dakota University
MSc. Drug Toxicology and Safety Pharmacology -
University of Bradford
Bsc. (Hons) Biomedical Science -
University of Bradford