Ammar Haq
San Antonio,Texas
Summary
Graduate student in Biomedical Technology & Commercialization with research experience in the antioxidative, antimicrobial, and oncologic applications of medicinal honey and current training in orthopedic implant prototyping and regulatory design controls. Aspires to advance both natural product–based therapeutics and patient-centered medical device development, bridging translational research with innovation in healthcare solutions.
Overview
3
3
years of professional experience
1
1
Certification
Work History
Graduate Student | Orthopedic Device Design
Nvision Biomedical Technologies
San Antonio, TX
08.2025 - Current
- Partnering with Nvision Biomedical to design a minimally invasive distal metatarsal implant for hallux valgus (intermetatarsal angle ~18–20°), targeting ≥50% IMA reduction while preserving joint congruency.
- Using Soft Chalk CAD software to model the 1st metatarsal and produce one working prototype via 3D metal additive manufacturing (Ti-6Al-4V ELI), validating virtually with finite element analysis (FEA) under forefoot loading of approximately 1,200–1,800 N to ensure fatigue resistance greater than 10⁶ cycles.
- Developing a Design History File (DHF) in compliance with FDA 21 CFR 820.30 and ISO 13485, incorporating design inputs such as pullout strength ≥1,200 N, insertion torque 2.5–3.0 N·m, and surface roughness Ra 3–5 μm, supported by FMEA risk thresholds (RPN < 100) for translational feasibility and future 510(k) submission.
Clinical Research Intern (Co-Associate)
ThinkNeuro, LLC
Berkeley, California
02.2025 - 05.2025
- Investigated parallels between CAG repeat expansion in Huntington’s disease (~2–6 repeat gains per neuronal division) and mechanisms of osteosarcoma-driven bone remodeling, emphasizing how DNA mismatch repair dysfunction (MSH2/MSH3, MLH1, FAN1), and replication stress contribute to genomic instability in both contexts.. Analyzed how RANKL overexpression (~3–5× baseline in osteosarcoma tissue) drives osteoclastogenesis and bone resorption, mirroring repeat-induced instability cascades that culminate in cell death and pathological remodeling.
- Presented findings as a co-associate researcher with ThinkNeuro to ~150 attendees, detailing therapeutic implications of modulating DNA repair pathways and bone tumor signaling. Proposed strategies included antisense oligonucleotides to suppress HTT transcription, CRISPR/Cas9-mediated excision of pathogenic repeats, and RANKL inhibition (≥60% reduction in osteoclast activity in preclinical models) as dual-use interventions bridging neurodegeneration and bone oncology.
Undergraduate Research Assistant - HONEY Pathway
The University of Texas at San Antonio
San Antonio, TX
08.2022 - 05.2023
- Performed Ferric Reducing Antioxidant Power (FRAP) assays to quantify electron-donating capacity of local Texas honey samples by monitoring reduction of Fe³⁺–TPTZ complex to Fe²⁺ at λ = 593 nm.
- Conducted DPPH radical scavenging assays, measuring honey’s ability to quench 2,2-diphenyl-1-picrylhydrazyl free radicals via absorbance decay at λ = 517 nm, generating IC₅₀ values for comparative antioxidative strength.
- Applied XTT reduction assays to assess cellular redox activity by measuring reduction of tetrazolium salts to formazan, quantifying metabolic/antioxidative effects in vitro.
- Evaluated honey’s antimicrobial activity against Staphylococcus aureus using agar diffusion (ZOI: – mm at 25–100% v/v), MIC/MBC assays (growth inhibition at ___% v/v; bactericidal at % v/v), and biofilm inhibition (OD570 reduction –%), with efficacy linked to **pH ~** and moisture –%.
- Investigated honey’s potential as an adjuvant therapy for glioblastoma multiforme (GBM) and osteosarcoma, using XTT assays to show a 35–50% reduction in mitochondrial dehydrogenase activity in GBM cells at concentrations of –% v/v, and proposing mechanisms including ROS-mediated apoptosis, disruption of tumor metabolic pathways, and inhibition of RANKL-driven osteoclastogenesis in bone tumors.
- Presented findings at the 1st Annual Course-Based Undergraduate Research Experience (CURE) Symposium (~100 attendees) via a poster summarizing antioxidant activity (FRAP absorbance shift at 593 nm; DPPH IC₅₀ values – μg/mL), antimicrobial efficacy (zones of inhibition – mm; MIC ___% v/v), and oncologic translational applications, while addressing faculty questions on reproducibility and clinical feasibility.
Education
Master of Science - Biomedical Technology Commercialization
The University of Texas At San Antonio
San Antonio, TX05-2026
Bachelor of Science - Biology
The University of Texas At San Antonio
San Antonio, TX05-2025
Skills
- Leadership & Mentorship
- Public Speaking & Presentation
- Cross-Cultural Communication (English/Urdu)
- Team Collaboration
- Problem-Solving & Adaptability
- Community Engagement & Advocacy
- Project & Time Management
- Conflict Resolution
Languages
English
Native/ Bilingual
Urdu
Native/ Bilingual
Arabic
Limited
Certification
- UTSA New Employee Compliance Training
- UTSA Campus Carry Training
- UTSA Hazard Communications & Laboratory Safety
- CRLA International Tutor Level I
Accomplishments
- UTSA Presidential Scholarship (Issued Jan 2022)
- UTSA Honors College Graduate (Issued May 2025)
- Certificate of Recognition - HONEY Pathway (Issued May 2023)
Leadership
- UTSA Muslim Student Association (Education Chair, 2023-2024)
- UTSA Pakistani Students Association (Advisor, 2023-2025)
- Pages of Promise (Lead Men's Instructor, 2024-Present)
- ThinkNeuro, LLC (Co-Associate)
Affiliations
Charity Week International Unity Project for Orphans:
(Volunteer & Ambassador: 2022-2024)
El Bari Charity Clinic:
(Volunteer, 2024 - Present)
Pages of Promise:
(Men's English Instructor for Refugees, 2024 - Present)
UTSA Roadrunner Activities Assistant:
(Volunteer, 2023-2023)
Founder: From the Grains of the Desert Historical Blog (2025 - Present)
Technical Skills
- Biomedical Assays & Analysis: FRAP, DPPH, XTT metabolic assays; spectrophotometry; refractometry; agar diffusion, MIC/MBC, and biofilm inhibition assays
- Microbiology & Molecular Biology: DNA repair pathway analysis (MSH2/MSH3, MLH1, FAN1); Huntington’s Disease CAG repeat modeling; antimicrobial/antioxidant profiling
- Orthopedic Device Design: CAD modeling with Soft Chalk; anatomical modeling; 3D metal additive manufacturing (Ti-6Al-4V ELI); finite element analysis (FEA); cadaver validation testing
- Regulatory & Quality Systems: Design History File (DHF) preparation; FDA 21 CFR 820.30 design control; ISO 13485 compliance; Failure Mode and Effects Analysis (FMEA); risk assessment (RPN thresholds)
References
- Dr. Hans Heidner:
hans.heidner@utsa.edu
- Dr. Ferhat Ozturk:
ferhat.ozturk@utsa.edu
- Dr. Faheem Ahmed:
faheem.ahmed@hcahealthcare.com
Timeline
Graduate Student | Orthopedic Device Design
Nvision Biomedical Technologies
08.2025 - Current
Clinical Research Intern (Co-Associate)
ThinkNeuro, LLC
02.2025 - 05.2025
Undergraduate Research Assistant - HONEY Pathway
The University of Texas at San Antonio
08.2022 - 05.2023
Master of Science - Biomedical Technology Commercialization
The University of Texas At San Antonio
Bachelor of Science - Biology
The University of Texas At San Antonio
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