Anand Joshi
Dublin,USA
Summary
Accomplished DMPK Project Representative and Subject Matter Expert with a combined 7 years of industry experience. Proven track record of spearheading 2 oncology projects through candidate nomination and globally leading CYP Induction assay support for the pipeline.
Overview
7
7
years of professional experience
Work History
Sr. Scientist II
AbbVie
South San Francisco, California
08.2022 - Current
- Lead DMPK project representative on two oncology projects: Independently spearheaded the transition of two oncology programs through Candidate Nomination/Selection
- Key project representative activities include- Deep-dive into in vitro ADME data, preclinical in vivo PK data, designing efficacy studies, human PK and dose projections, guidance on safety/tox studies to establish optimal safety margins
- Lead for CYP Induction: Successfully supported over 20 small molecule/ADC programs from multiple disease areas through Candidate Nomination/Selection
- Lead author on regulatory IND reports: Authored CYP Induction section of over 20 IND reports
- Introduced methodologies that would improve assay efficiency, generated data that would support the preference to use certain DDI models over others in the established workflow
Sr. Scientist I
AbbVie
South San Francisco, California
03.2019 - 07.2022
- Designed and conducted multiple in vitro ADME assays to support early-stage discovery
- Global Lead for discovery stage MetID assay in s9 subcellular fractions
Education
Research Scientist/Postdoc Training - Pharmaceutical Sciences
University of Pittsburgh
Pittsburgh, PA03-2016
Postdoc Associate - Pharmaceutical Sciences
Virginia Commonwealth University
Richmond, Virginia, VA06-2013
Ph.D. - Medicinal Chemistry
University of Kansas
Lawrence, KS05-2013
Master of Science - Medicinal Chemistry
NIPER
Mohali, India07-2007
Skills
- DMPK Project Representative
- SME (CYP Induction)
- In vitro/in vivo ADME/PK analysis
- Regulatory IND reports
- Preclinical drug development
- Efficacy/Tox study design
- Cross-functional collaboration
- Team leadership
Volunteer Experience
- Reviewer, Molecular Pharmaceutics, Cancer Chemo. and Pharm. and multiple relevant peer reviewed scientific journals
- Secretary, KU Cultural India Club, Lawrence, KS
- Founding Member, SPIC-MACAY, KU, Lawrence, KS
Google Scholar
https://scholar.google.com/citations?user=EEWAzFcAAAAJ&inst=10413501135572360971
Timeline
Sr. Scientist II
AbbVie
08.2022 - Current
Sr. Scientist I
AbbVie
03.2019 - 07.2022
Research Scientist/Postdoc Training - Pharmaceutical Sciences
University of Pittsburgh
Postdoc Associate - Pharmaceutical Sciences
Virginia Commonwealth University
Ph.D. - Medicinal Chemistry
University of Kansas
Master of Science - Medicinal Chemistry
NIPER