Anchal Agarwal

Postdoctoral researcher in gene regulation and RNA biology with a Ph.D. in Regulatory Biology. Research expertise in RNA-binding proteins and translational control, integrating high-throughput approaches including ribosome profiling (Ribo-seq), eCLIP-seq, and polysome profiling with mechanistic validation. Current work focuses on post-translational regulation of lipid metabolism and metabolic adaptation under stress conditions. Experienced in hypothesis-driven research, integrative data analysis, and collaborative projects in academic research environments.

Anderson R, Agarwal A, Ghosh A, Guan BJ, Casteel J, Dvorina N, Baldwin WM 3rd, Mazumder B, Nazarko TY, Merrick WC, Buchner DA, Hatzoglou M, Kondratov RV, Komar AA. eIF2A-knockout mice reveal decreased life span and metabolic syndrome. FASEB J. 2021 Nov;35(11): e21990. doi: 10.1096/fj.202101105R. PMID: 34665898

MANUSCRIPTS IN PREPARATION

Agarwal A, et al. “CLIP-seq analysis of eIF2A targets reveals a novel mode of protein action.” Manuscript in preparation, expected submission: Summer 2025.

• Anchal Agarwal, Richard Anderson, Frank Tedeschi, Soon Yeul Yi, Bo-Jhih Guan, Archana Prabahar, Barsanjit Mazumder, William C. Merrick, David A. Buchner, Maria Hatzoglou, Peng Jiang and Anton A. Komar, “Transcriptome and eCLIP-seq analyses of eIF2A targets in 3T3-L1 mouse cells”, Hear and Vascular Impact Area Research Forum, Lerner’s Research Institute, Cleveland Clinic, Cleveland, (USA), September 24, 2025.
• Anchal Agarwal, Richard Anderson, Frank Tedeschi, Soon Yeul Yi, Bo-Jhih Guan, Archana Prabahar, Barsanjit Mazumder, William C. Merrick, David A. Buchner, Maria Hatzoglou, Peng Jiang and Anton A. Komar, “Transcriptome and eCLIP-seq analyses of eIF2A targets in 3T3-L1 mouse cells”, Cold Spring Harbor Laboratory Translational Control meeting, Cold Spring Harbor, (USA), September 3–7, 2024.
• Richard Anderson, Anchal Agarwal, Barsanjit Mazumder, Roman V. Kondratov, David A. Buchner, William C. Merrick, Maria Hatzoglou, and Anton A. Komar, “Adipocyte specific eIF2A-KO mouse model”, Cold Spring Harbor Laboratory Translational Control meeting, Cold Spring Harbor, (USA), September 3–7, 2024.
• Ankit Shroff, Theresah Mensah, Chetna Batra, Anchal Agarwal, Anton Glieder, Anton Komar, Taras Y. Nazarko. “Yeast lipophagy is regulated by translation initiation factors, eIF2A and Fun12”. Keystone Conference on Autophagy, Keystone, Colorado (USA), December 3-6, 2023.
• Ankit Shroff, Theresah Mensah, Chetna Batra, Anchal Agarwal, Anton Glieder, Anton Komar, Taras Y. Nazarko. “Translation initiation factors, eIF2A and Fun12, repress lipid droplet degradation in yeast”. 2nd Annual GSU Postdoc Symposium, Georgia, (USA), September 22, 2023.
• Richard Anderson, Anchal Agarwal, Arnab Ghosh, Bo-Jhih Guan, Jackson Casteel, Dvorina N, Baldwin WM 3rd, Mazumder B, Nazarko TY, Merrick WC, Buchner DA, Hatzoglou M, Kondratov RV, Komar AA. "Reduced life span and metabolic syndrome phenotype in eIF2A-knockout mouse model". EMBL Conference “Protein Synthesis and Translational Control” (Virtual), September 7–10, 2021.
• Participated in multiple international symposia and cytometry workshops during M.Sc. training (2010–2011)

• Member, RNA Society, 2025–present
• Member, American Society for Cell Biology (ASCB), 2025–present
• Member, National Postdoctoral Association (NPA), 2024–present
• Reviews linked via ORCID: https://orcid.org/0009-0004-2183-9478

• Graduate Student Award for “Outstanding Achievement Award for Doctoral Research in Natural Sciences” at Cleveland State University, OH. 2023.
• Invited as distinguished Alumni on behalf of “Panjab University Alumni Association” for the “Fourth Annual Global Alumni Meet” to present my research. 2023.
• Graduate Research Assistant: Cleveland State University 2020-2024, Graduate Teaching Assistant: Cleveland State University 2017-2020.
• Appreciation award for “Innovative Idea” on “Targeting Cancer Stem Cells” at the International Symposium on Cancer Research: a translation Initiative cum Workshop on Flow Cytometry at Panjab University, Chandigarh. 2011.

• Anchal Agarwal, Anton A. Komar. Control of lipid metabolism by the eukaryotic initiation factor 2A (eIF2A). Poster Presentation, Research Day at the College of Science and Health Professions; Cleveland State, OH. April 2022.
• Anchal Agarwal, Anton A. Komar. Control of lipid metabolism by the eukaryotic initiation factor 2A (eIF2A). Poster Presentation, Research Day at the College of Arts and Sciences; Cleveland State, OH. April 2024.

• Anchal Agarwal.Control of lipid metabolism by the eukaryotic initiation factor 2A (eIF2A). Oral Research Presentation, Center for Gene Regulation in Health and Disease (GRHD), Cleveland, OH. September 2019.
• Anchal Agarwal, Control of lipid metabolism by the eukaryotic initiation factor 2A (eIF2A). Oral Research Presentation, Center for Gene Regulation in Health and Disease (GRHD), Cleveland, OH. April 2023.
• Anchal Agarwal, Control of lipid metabolism by the eukaryotic initiation factor 2A (eIF2A). Oral Research Presentation, Center for Gene Regulation in Health and Disease (GRHD), Cleveland, OH. March 2024.