Anil Kumar Kalvala
Abilene
Summary
Accomplished researcher with extensive experience at TTUHSC, specializing in extracellular vesicle isolation and cancer metastasis. Proven ability to lead projects, train teams, and present findings at international conferences. Skilled in molecular techniques and data analysis, with a strong focus on innovative methodologies and collaborative success.
Overview
4
4
years of professional experience
Work History
HSC Postdoc Research Associate
TTUHSC
Abilene
06.2022 - Current
- Developed new methods to isolate pure and quality extracellular vesicles from TSC2-null LAM patient-derived cells.
- Developed new experiments to identify the cancer potentials of these LAM-derived EVs in LAM cancer metastasis.
- Utilized various molecular techniques to study the role of these extracellular vesicles in cancer metastasis.
- Supervised one master's student and two PhDs in designing and performing their work.
- Developed Lenti viral transfected cells to study the specific molecular pathways in LAM cancer metastasis.
- Worked on siRNA-transfected cells.
- Explored the role of mitochondrial physiology in LAM metastasis, linking to the integrin signaling pathway.
- Data analysis and helped the PI in writing reports for publications and grant submissions.
- Introduced and standardized a variety of molecular experiments to prove the cancer progression in LAM.
- Presented research findings at international conferences.
- Used databases, physical records, and digital resources to complete in-depth research.
- Performed a variety of laboratory tests on samples, including ELISA, preparing samples for transcriptomics and proteomics, cell culture, western blotting, qPCR assays, and flow cytometry.
- Produced comprehensive research questions and potential hypotheses.
- Kept lab space and equipment clean to prevent contamination with hazardous substances.
- Managed inventory and supplies to ensure materials were available when needed.
- Collaborated closely with team members to achieve project objectives and meet deadlines.
Postdoctoral Research Associate
FAMU
Tallahassee
12.2020 - 05.2022
- Developed pain models in neuronal cell lines and rodents.
- Experienced in isolating extracellular vesicles from human umbilical cord-derived stem cells.
- Conducted studies on breast cancer and lung cancer.
- Screened potential therapeutic applications of non-psychoactive cannabinoids in cancer and pain models.
- Used various molecular techniques to demonstrate the extracellular vesicles isolated from human-derived stem cells and cannabinoids, alone or in combination, in mitigating pain and cancer.
- Interpreted test results and determined need for retesting.
- Provided technical support to other researchers in the lab.
- Trained PhD students on proper laboratory techniques and procedures.
- Prepared detailed reports summarizing experimental findings.
- Supervised supplies in inventory and notified supervisor of low stock levels.
- Presented research findings at national and international conferences.
- Designed new experiments based on previous work or existing literature reviews.
- Actively participated in weekly meetings with the research team to discuss progress towards project goals.
- Created presentations to explain research findings to colleagues and supervisors.
- Reviewed experimental data to catch potential lab errors and correct mistakes.
- Maintaining proper lab records, consumables indents, and other lab supplies.
Education
Ph.D. - Pharmacology And Toxicology
NIPER-Hyderabad
Hyderabad, India09-2020
Master of Science - Pharmacology And Toxicology
NIPER-Hyderabad
Hyderabad, India09-2014
Skills
- Extracellular vesicle isolation
- Cell culture
- Animal studies
- Neuro-behavioral and functional studies
- Functional studies related to cancer metastasis
- Molecular techniques: confocal microscopy, Western blotting, ELISA, flow cytometry, transcriptomics, and proteomics
- shRNA and siRNA transfection studies
- Mitochondrial-related functional studies
- Publications and Grant writing
- Data analysis
- Team collaboration
- Project management
- Research presentation
- Statistical analysis
Timeline
HSC Postdoc Research Associate
TTUHSC
06.2022 - Current
Postdoctoral Research Associate
FAMU
12.2020 - 05.2022
Ph.D. - Pharmacology And Toxicology
NIPER-Hyderabad
Master of Science - Pharmacology And Toxicology
NIPER-Hyderabad
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