Arif Hussain, MD

Currently serving as a postdoctoral research fellow in the Surgery Department at Indiana University, I bring a wealth of experience and expertise garnered from my previous role as a clinical research fellow at Mayo Clinic, Rochester. My research pursuits span a diverse spectrum, including acute and chronic endotheliopathy, immunothrombosis, regenerative medicine, and lymphedema, covering fundamental science, translational, and clinical research domains.

My extensive clinical background across various surgical disciplines has been cultivated through training in both academic and community residency programs, both domestically and internationally. This multifaceted experience has positioned me to pursue specialized training in vascular surgery, with the ultimate aim of contributing as an academic vascular surgeon and physician-scientist.

In addition to my clinical and research aspirations, I am deeply committed to enhancing surgical education, fostering academic leadership, and actively participating in global surgery initiatives. These passions drive my overarching goal of making meaningful contributions to the field while positively impacting patient care on a global scale.

• ECFMG
• ATLS
• ALS
• ILS
• HIPPA
• EMR/CERNER/EPIC
• HUMAN RESEARCH SUBJECTS HANDLING
• ANIMAL RESEARCH SUBJECTS HANDLING

• English (Advance)
• Urdu (Advance)
• Punjabi (Basics)
• Hindi (Advance)
• Sheena (Native)
• Brushiski (Native)

• Research Fellow, Plastic Surgery Dept. Mayo Clinic (9/21-5/22)
• Post-Doc Fellowship, Plastic Surgery, Indiana University (5/22-Current)

Published Papers:

1. Exosome-based therapies for soft tissue regeneration

2. Lymphaticovenous Anastomosis (LVA) for Preventing Lymphedema

3. Review of the Literature, The Role of Sensory Innervation in Homeostatic and Injury-Induced Corneal Epithelial Renewal

4. Overview of Unilateral and Bilateral Pediatric Facial Paralysis: Workup, Treatment, and Frontiers

Completed, Submitted Papers:

1.  A retrospective study and literature review of the Chronic Nonbacterial Osteomyelitis of the Hand and Upper Extremity

2. Narrative Review and Case Series: Saphenous Flap for H&N Reconstruction

3. Corneal Neurotization: Essentials for the Facial Paralysis Surgeon

Current Projects and Expected Publications at Dr. Borschel's Lab, Indiana University: 

1. Trophic Growth Factors for Corneal Epithelial Regeneration in Neurotrophic Keratopathy

2. Unraveling NGF mechanisms in corneal epithelial renewal: Paving the way for innovative therapeutics for Neurotrophic Keratopathy

3. Defining the Role of Mesenchymal Stem Cells in corneal epithelial Regeneration, Therapeutic Potential of Neuropeptides in Corneal Epithelial Regeneration

4. A New Rodent Model of Neurotrophic Keratopathy

5. A Systematic Review and Meta-analysis: Outcomes of Corneal Transplant in Neurotrophic Keratopathy

• PA Medical Training 2017-18
• DC Medical Training 2018-19
• Qatar Council for Healthcare Practitioners 2019-Current
• Pakistan Medical Council 2013-Current

• First Place, Basic Science Abstracts Presentation, Annual Research Day, Plastic Surgery Division, Indiana University 2024
• Professor Najmuddin Scholarship, KEMU, Pakistan, 2013
• First Position, HSCC Exam, Gilgit, Pakistan
• First Position, Medical Entrance Exam, Gilgit, Pakistan
• Certificate of appreciation, for the outstanding COVID patients' care, Qatar, 2020

• Dr. Gregory Borschel, MD, FACS, Professor of Plastic Surgery, Chair Plastic Surgery Riley Children's Hospital, Indiana University, gborschel@iu.edu
• Dr. Steven, L Moran, MD, FACS, Professor of Plastic Surgery, Mayo Clinic, Rochester, MN, Moran.Steven@mayo.edu

• Founded Helping Hands, Gilgit Baltistan, 2009
• Free Medical Camp, Gilgit, Pakistan 2015/2016
• Dengue Virus Epidemic Volunteer, Lahore, Pakistan 2013
• COVID Pandemic Volunteer, Qatar 2020
• Free Medical Camp in underserved areas, Pakistan 2021

1. Chronic Recurrent Multifocal Osteomyelitis of the Hand and Upper Extremity: A Case Series About This Rare Condition

Poster Presentation at ASSH Meeting 2022

2. Corneal Epithelial Regeneration: Corneal Nerves Regulate the Activity of Limbal Stem Cells via Mesenchymal Limbal Niche Cells

Poster presentation Annual Surgery Research Day 2022 at Riley Children's Hospital, Indiana

3. Schwann Cells-secreted Trophic Factors Maintain Corneal Epithelial Regenerative Capacity: A Potential Novel Therapy for Neurotrophic Keratopathy

Poster Presentation Annual Plastic Surgery Research Day 2024, Indiana University

4. Unraveling NGF Mechanisms in Corneal Epithelial Renewal: Paving the way for Innovative Therapeutics for Neurotrophic Keratopathy

Poster Presentation Annual Plastic Surgery Research Day 2024, Indiana University

5. Nerve-Guided Harmony: Corneal Nerves as Conductors of Limbal Stem Cells and Mesenchymal Stem Cells in Epithelial Regeneration

Poster Presentation Annual Plastic Surgery Research Day 2024, Indiana University

6. Retro-Orbital Nasociliary Nerve Transection: A Novel Approach to a Reliable Rodent Model for Neurotrophic Keratopathy

Poster Presentation Annual Plastic Surgery Research Day 2024, Indiana University

7. Unraveling NGF mechanisms in corneal epithelial renewal: Paving the  way for Innovative Therapeutics for Neurotrophic Keratopathy

Accepted for podium presentation at PSRC meeting, 2024

8. Unforeseen Challenges: Discussing the Overlooked Hurdles in  Electrospinning Implementation

Poster Presentation Annual Plastic Surgery Research Day 2024, Indiana University

9. Early Clot Formation After Blunt Thoracic Trauma: Insights from Pulmonary and Systemic Vasculature

Podium Presentation Annual Academic Surgical Congress, 2024

• Research Fellow, Plastic Surgery Dept. Mayo Clinic (9/21-5/22)
• Post-Doc Fellowship,Surgery Department, Indiana University (5/22-Current)

Published Papers:

1. Exosome-based therapies for soft tissue regeneration

2. Lymphaticovenous Anastomosis (LVA) for Preventing Lymphedema

3. Review of the Literature, The Role of Sensory Innervation in Homeostatic and Injury-Induced Corneal Epithelial Renewal

4. Overview of Unilateral and Bilateral Pediatric Facial Paralysis: Workup, Treatment, and Frontiers

Completed, Submitted Papers:

1.  A retrospective study and literature review of the Chronic Nonbacterial Osteomyelitis of the Hand and Upper Extremity

2. Narrative Review and Case Series: Saphenous Flap for H&N Reconstruction

3. Corneal Neurotization: Essentials for the Facial Paralysis Surgeon

Current Projects and Expected Publications at Dr. Borschel's Lab, Indiana University: 

1. Trauma Endotheliopathy of Pulmonary Vasculature and Early Clot formation

2. Trauma Endotheliopathy of systematic vasculature

3.  Tranexamic acid and Enotheliopathy of trauma

4. Immunothrombosis of trauma

5. Chronic Pulmonary Endotheliopathy

6. Trophic Growth Factors for Corneal Epithelial Regeneration in Neurotrophic Keratopathy

7. Unraveling NGF mechanisms in corneal epithelial renewal: Paving the way for innovative therapeutics for Neurotrophic Keratopathy

8. Defining the Role of Mesenchymal Stem Cells in corneal epithelial Regeneration, Therapeutic Potential of Neuropeptides in Corneal Epithelial Regeneration

• English (Advance)
• Urdu (Advance)
• Punjabi (Basics)
• Hindi (Advance)
• Sheena (Native)
• Brushiski (Native)

• PA Medical Training 2017-18
• DC Medical Training 2018-19
• Qatar Council for Healthcare Practitioners 2019-Current
• Pakistan Medical Council 2013-Current

• First Place, Basic Science Abstracts Presentation, Annual Research Day, Surgery Department, Indiana University 2024
• Professor Najmuddin Scholarship, KEMU, Pakistan, 2013
• First Position, HSCC Exam, Gilgit, Pakistan
• First Position, Medical Entrance Exam, Gilgit, Pakistan
• Certificate of appreciation, for the outstanding COVID patients' care, Qatar, 2020

• Dr. Gregory Borschel, MD, FACS, Professor of Plastic Surgery, Chair Plastic Surgery Riley Children's Hospital, Indiana University, gborschel@iu.edu
• Dr. Steven, L Moran, MD, FACS, Professor of Plastic Surgery, Mayo Clinic, Rochester, MN, Moran.Steven@mayo.edu

• Founded Helping Hands, Gilgit Baltistan, 2009
• Free Medical Camp, Gilgit, Pakistan 2015/2016
• Dengue Virus Epidemic Volunteer, Lahore, Pakistan 2013
• COVID Pandemic Volunteer, Qatar 2020
• Free Medical Camp in underserved areas, Pakistan 2021

1. Chronic Recurrent Multifocal Osteomyelitis of the Hand and Upper Extremity: A Case Series About This Rare Condition

Poster Presentation at ASSH Meeting 2022

2. Corneal Epithelial Regeneration: Corneal Nerves Regulate the Activity of Limbal Stem Cells via Mesenchymal Limbal Niche Cells

Poster presentation Annual Surgery Research Day 2022 at Riley Children's Hospital, Indiana

3. Schwann Cells-secreted Trophic Factors Maintain Corneal Epithelial Regenerative Capacity: A Potential Novel Therapy for Neurotrophic Keratopathy

Poster Presentation Annual Plastic Surgery Research Day 2024, Indiana University

4. Unraveling NGF Mechanisms in Corneal Epithelial Renewal: Paving the way for Innovative Therapeutics for Neurotrophic Keratopathy

Poster Presentation Annual Plastic Surgery Research Day 2024, Indiana University

5. Nerve-Guided Harmony: Corneal Nerves as Conductors of Limbal Stem Cells and Mesenchymal Stem Cells in Epithelial Regeneration

Poster Presentation Annual Plastic Surgery Research Day 2024, Indiana University

6. Retro-Orbital Nasociliary Nerve Transection: A Novel Approach to a Reliable Rodent Model for Neurotrophic Keratopathy

Poster Presentation Annual Plastic Surgery Research Day 2024, Indiana University

7. Unraveling NGF mechanisms in corneal epithelial renewal: Paving the  way for Innovative Therapeutics for Neurotrophic Keratopathy

Accepted for podium presentation at PSRC meeting, 2024

8. Unforeseen Challenges: Discussing the Overlooked Hurdles in  Electrospinning Implementation

Poster Presentation Annual Plastic Surgery Research Day 2024, Indiana University

9. Early Clot Formation After Blunt Thoracic Trauma: Insights from Pulmonary and Systemic Vasculature

Podium Presentation Annual Academic Surgical Congress, 2024