Summary
Work History
Education
Skills
Accomplishments
Work Availability
Timeline
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Arunima Purkayastha, PhD

Arunima Purkayastha, PhD

Senior Scientist
San Diego,CA

Summary

Critical thinker, highly innovative and independent molecular and cell biologist with extensive (14+ years) hands-on laboratory experience in life science industry and academia. Extensive experience in experimental design and troubleshooting, data analysis, literature survey, writing research manuscripts, grants and SOPs, conference presentations-demonstrated by 14 peer-reviewed publications in high impact journals, 1 book chapter, 1 patent, 10+ conference presentations, 2 invited lectures, 30+ review of articles. Strong communication, mentoring and time management skills. Seeking an opportunity as a scientist to utilize extensive knowledge, skills and hands-on experience in the pharmaceutical and/or biotechnology innovation space.

Work History

Senior scientist

HD Biosciences (WuXi AppTec Subsidiary)
San Diego, CA
07.2022 - 05.2023
  • • ~1 year experience as Senior Scientist. Responsible for leading projects (design, execute, troubleshoot, data-analysis and presentation) for SMID and Large-cap biopharma/biotech clients focusing on areas including, but not limited to gene-therapy, cell-based high-throughput screening for drug discovery , infectious diseases, oncology using cell and molecular biology techniques. Involved in multiple projects individually and in team setting to meet aggressive timelines.
    • Led and completed 5 client projects, contributed to 2 projects and established assays for internal development.
    • Data Analysis: Graphpad Prism, MS Excel, ImageJ, Harmony etc.
    • Data Preparation and Communication: Clear and concise presentation of data regularly to internal and external stakeholders (including scientists, KOLs and management).
    • Mentoring: Mentored and led team of 2 research associates and 1 junior scientist (1 direct report).
    • Writing: Preparation of proposal and quotes for commercial contract, SOPs, data files and study reports for various stakeholders.

Assistant Project Scientist

University of California, Los Angeles
Los Angeles, CA
01.2018 - 01.2022
  • • 4+ years experience as a project scientist in respiratory epithelial stem cells in disease (COVID19, CF) and drug screening.
    • Performed projects investigating role of smoking in aggravating SARS-Cov-2 infections in human airway epithelium (Purkayastha A et al., Cell Stem Cell, 2020) and deleterious impact of e-cig juices on rodent and human airway epithelium (under review).
    • Contributed to multiple cross-collaborative projects including high-throughput drug screen against SARS-Cov2 (under review).
    • Published 8 research articles in high impact journals including Cell Stem Cell, Nature Medicine, Cell Reports.
    • Grantspersonship: Contributed to drafting 5 grants, scientific manuscripts.
    • Presentation and communication: Presented research at multiple platforms, including international conferences.
    • Mentoring: Mentored and trained 5 undergraduates, graduate students and junior postdocs.

Postdoctoral Fellow

University of California, Los Angeles
Los Angeles, CA
01.2012 - 01.2017
  • •4+ years - cellular signal transduction and cancer metabolism.
    •Investigated Cell Signaling and Metabolic shift in Receptor Tyrosine Kinase (RTK)-Induced tumor model in Drosophila.
    •Led project investigating role of glycolytic enzyme in RTK-induced tumors.
    •Co-authored 1 research article (another in preparation), contributed to NIH-R01 grants. Regularly presented work at academic meetings.

PhD Graduate Student

University of Delhi
New Delhi, India
01.2004 - 01.2011

• PhD student in molecular biology and virology.
• Functional Genomics: Developed RNAi- based gene silencing vector for functional genomics in rice.
• Published 4 articles, 1 book chapter and 1 patent.
• Demonstrated ability to work independently and collaboratively.

Education

PhD - Molecular Biology

University of Delhi
08.2004 - 02.2011

Master of Science - Biochemistry

University of Calcutta
India
08.2001 - 08.2003

Bachelor of Science - Biochemistry

North Eastern Hill University
India
1999 - 2001

Skills

Primary Stem Cell Isolation and Maintenance in Culture (human and mice trachea)

Aseptic Cell Culture Techniques: Air-liquid interface (ALI)-, 3D-, adherent-, non adherent cell line- culture in BSL2 and BLS2 setting

Cell Based Assays: DHE-(ROS), luminescence, CTG, cell-proliferation, migration, toxicity-assay

Molecular Biology: DNA- and RNA- isolation, primer design, cloning and expression ddPCR, PCR, qRT-PCR, site-directed mutagenesis, Northern blotting, Western blotting, and RNA-Seq library preparation

Microscopy: Confocal microscopy, high-content imaging (Opera Phenix), fluorescence light microscopy, IF, IHC

Liquid Handlers: Combi/multi drop, Echo Plate Readers: Envision

Softwares: ELN, Image-J, Fiji, Harmony (image analysis), Statistical analysis using Graphpad-Prism, Excel, MS Office

Soft Skills: Analytical, team player, collaborative, multitasking, mentoring, communication, presentation, peer-reviewing, project-management

Accomplishments

PUBLICATIONS

‪Arunima Purkayastha - ‪Google Scholar

PATENT

Arunima Purkayastha, Indranil Dasgupta. A DNA construct for gene silencing in rice. Indian Patent no. 278167

FELLOWSHIPS

National Eligibility Test Junior and Senior Research Fellowship (2004)

General Aptitude Test for Engineering (2004)

Work Availability

monday
tuesday
wednesday
thursday
friday
saturday
sunday
morning
afternoon
evening
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Timeline

Senior scientist

HD Biosciences (WuXi AppTec Subsidiary)
07.2022 - 05.2023

Assistant Project Scientist

University of California, Los Angeles
01.2018 - 01.2022

Postdoctoral Fellow

University of California, Los Angeles
01.2012 - 01.2017

PhD Graduate Student

University of Delhi
01.2004 - 01.2011

Master of Science - Biochemistry

University of Calcutta
08.2001 - 08.2003

Bachelor of Science - Biochemistry

North Eastern Hill University
1999 - 2001

PhD - Molecular Biology

University of Delhi
Arunima Purkayastha, PhDSenior Scientist