Summary
Overview
Work History
Education
Skills
Publications
References
Training
Personal Information
painting, horseback riding
Timeline
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Arvin MEDHAT

Arvin MEDHAT

Philadelphia,PA

Summary

With extensive experience in molecular cell biology and microbiology, I have developed a strong foundation that, combined with professional clinic and OR assistantship in the orthopedic field, has enhanced my intellectual ability and laboratory skills. This has allowed me to become a knowledgeable and independent individual capable of managing and leading various research projects in medical science. Currently, my focus is on elucidating the molecular mechanisms underlying chronic diseases, particularly Metabolic Dysfunction-Associated Steatohepatitis.

Overview

22
22
years of professional experience

Work History

PhD student

Temple University
06.2024 - Current

Research assistant

Dr. Feitelson lab
06.2023 - Current
  • Working on functional cure for Chronic liver disease.

Orthopedic Surgeon assistant

Mansour Abolghasemian
02.2018 - Current
  • Mostly Total hip and knee replacement (THR & TKR) surgeries and autograft cell therapy.

Research assistant

Pasteur Institute of Karaj and Tehran
01.2017 - 08.2017
  • Set up in vitro tests for evaluating in-process potency of veterinary rabies vaccine.

IPQC Manager and research assistant

GENEXIR Biopharma
04.2016 - 09.2016
  • Human rabies vaccine development.

QC Manager and Microbiological Analyst

RDD
08.2015 - 04.2016
  • ISO 17025 accredited laboratory of food and drug organization, ministry of health.

QC and R&D staff

GENEXIR Biopharma
05.2015 - 08.2015
  • Human rabies vaccine development.

Research assistant

Children Hospital of Tehran University
05.2014 - 05.2015
  • Preparing amniotic membrane as a natural scaffold for bladder abnormalities.

Research assistant

Shahid Beheshti Medical University
01.2011 - 04.2011
  • Designing army cloths that exchange color in different environments.

Research assistant

Taleghani Medical Hospital
05.2010 - 12.2010
  • Worked on Stem Cell Therapy and periodontal disease projects.

Marketing and R&D unit staff

Fargene Pouyesh Co.
02.2009 - 05.2010
  • Laboratory devices such as microscopes, RTPCR and single cell PCRs.

Research assistant

Urology & Nephrology Research Center
05.2008 - 07.2008
  • RNA Extraction and qrtPCR for monitoring protein expression in bladder cancer.

Microbiological Laboratory technician

Viromed accredited veterinary laboratory
04.2003 - 04.2004

Education

PhD student in Biology -

Temple University
Philadelphia, PA
10.2024

PhD student in molecular and cell biology -

Islamic Azad University of North Branch
Tehran, Tehran
10.2024

Master of Molecular cell Biology -

Khatam University and Tarbiat Modares University
Tehran, Tehran
09.2007

Bachelor of Science - Microbiology

Islamic Azad University (North Unit)
Tehran, Tehran
07.2003

Pre-university course -

Payam pre-university school
Tehran, Tehran
12.1998

Diploma in field of science -

Iran high school
Tehran, Tehran
12.1997

Skills

  • Immunohistochemistry methods and analysis
  • DNA and RNA extraction, PCR, RT-PCR, DNA and SDS-PAGE Electrophoresis, Affinity Chromatography, western blot
  • ELISA, RIA, HI, HA, MTT assay, Bradford assay, Immunohistochemistry staining, Focus Forming Assay for virus titration (FFA) and immunofluorescence (IF) staining
  • Cell culture techniques, tissue and bio-scaffold manipulation (amniotic membrane), Cell isolation ( ficoll hypaque & Nylon Wool)
  • Stem cell Therapy (on two cases model of Beurger & Lymphedema disease), Autograft therapy for patients with AVN
  • Microbial diagnostic tests such as antibiotic potency microbiological assay, sterility tests and The Limulus Amebocyte Lysate (LAL) assay for detecting soluble endotoxin
  • DNA Aptamer isolation (SELEX)
  • DNAsis
  • Oligo
  • Microsoft Office tools
  • Bioinformatics
  • PowerPoint presentation
  • SPSS Statistic
  • Cytoscape
  • EnrichR

Publications

  • Systematic evolution of specific DNA aptamer ligands by exponential enrichment (SELEX) for detection of Aflatoxin B1, Arvin Medhat, MirLatif Mousavi, Mohamad Javad Rassaee, 14th National and 2nd International Conference of Biology Iran, Tehran, Iran, 2006
  • Selection of DNA Aptamers for detection of Aflatoxin B1, Arvin Medhat, MirLatif Mousavi, Mohamad Javad Rassaee, Mehdi Forozande Moghadam, 5th National Biotechnology Congress of Iran, Tehran, Iran, 2007
  • Short chain fatty acids in cancer pathogenesis, Mark A. Feitelson, Alla Arzumanyan, Arvin Medhat, Ira Spector, Cancer and Metastasis Reviews, 06/05/23
  • Development of specified DNA aptamer binding to group A Streptococcus serotype M3, Canadian Journal of Microbiology, 10.1139/cjm-2016-0495
  • Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma, Arvin Medhat, Alla Arzumanyan, Mark A. Feitelson, Oncotarget, 2021
  • Hepatitis B x (HBx) as a Component of a Functional Cure for Chronic Hepatitis B, Mark A. Feitelson, Alla Arzumanyan, Ira Spector, Arvin Medhat, Biomedicines, 09/07/22, 10.3390/biomedicines10092210

References

  • Prof. Mark A. Feitelson, Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA, feitelso@temple.edu, +1(267) 317-6317
  • Prof. Seyyed Latif Mousavi, Shahed University, slmousavi@shahed.ac.ir, +98 21 55228813, +98 21 51216000
  • Prof. Mohamad Javad Rassaee, Tarbiat Modares University, rasaee_m@modares.ac.ir, +98 21 82884513
  • Dr. Farzaneh Sheykholeslami, WHO Collaborating Center for Reference and Research on Rabies, Pasteur Institute of Iran, Tehran, Tehran, Iran, f_sheikh@pasteur.ac.ir, +98-21-66953311-20 Ex: 2229, Fax: +98-21-66480777
  • Dr. Mansour Abolghasemian, Iran University of Medical Science, Orthopedic surgery, Tehran, Tehran, Iran, mabolghasemian@gmail.com

Training

  • RNA Extraction, cDNA synthesis and RT PCR Method in Shahed University
  • Microbial diagnostic tests such as antibiotic potency microbiological assay
  • The Limulus Amebocyte Lysate (LAL) assay for detecting soluble endotoxin
  • Oral presentation Methods in Tarbiat Modares University
  • Immunohistochemistry staining (IHC)

Personal Information

  • Date of Birth: 03/23/80
  • Gender: Female
  • Marital Status: Single

painting, horseback riding

Beside my professional carrier, I improved my skills as an artist in painting and sculpture making. I achieved a lot of medals and awards in show jumping and this part of my life is one I proud of. 

Timeline

PhD student

Temple University
06.2024 - Current

Research assistant

Dr. Feitelson lab
06.2023 - Current

Orthopedic Surgeon assistant

Mansour Abolghasemian
02.2018 - Current

Research assistant

Pasteur Institute of Karaj and Tehran
01.2017 - 08.2017

IPQC Manager and research assistant

GENEXIR Biopharma
04.2016 - 09.2016

QC Manager and Microbiological Analyst

RDD
08.2015 - 04.2016

QC and R&D staff

GENEXIR Biopharma
05.2015 - 08.2015

Research assistant

Children Hospital of Tehran University
05.2014 - 05.2015

Research assistant

Shahid Beheshti Medical University
01.2011 - 04.2011

Research assistant

Taleghani Medical Hospital
05.2010 - 12.2010

Marketing and R&D unit staff

Fargene Pouyesh Co.
02.2009 - 05.2010

Research assistant

Urology & Nephrology Research Center
05.2008 - 07.2008

Microbiological Laboratory technician

Viromed accredited veterinary laboratory
04.2003 - 04.2004

PhD student in molecular and cell biology -

Islamic Azad University of North Branch

Master of Molecular cell Biology -

Khatam University and Tarbiat Modares University

Pre-university course -

Payam pre-university school

Diploma in field of science -

Iran high school

PhD student in Biology -

Temple University

Bachelor of Science - Microbiology

Islamic Azad University (North Unit)
Arvin MEDHAT