Barsha Bastola
Columbia,MO
Summary
Problem-solving professional working successfully in fast-paced environments. Offering sharp writing and interpersonal skills. Looking for a role in the pharmaceutical sector where quality experience will be regarded with great esteem.
Overview
6
6
years of professional experience
1
1
Certification
Work History
SCIENTIST II
Eurofins BioPharma Product Testing
Columbia , MO
2023.08 - Current
- Charged with conducting method development and validation, compatibility, and stability studies (CNS), feasibility, toxicology studies, protein analysis, and qualification studies of pharmaceutical drugs, provided quality and timely data that informed specific client studies
- Engaged in cross-functional collaboration with multiple stakeholders to ensure the timely completion of method development and validation studies
- Operate High-performance liquid chromatography (HPLC), Gas Chromatography-Mass Spectrometry/ Flame Ionization Detector (MS/ FID), Liquid Chromatography-Mass Spectrometry (LCMS), UV-Vis spectrophotometer, SoloVPE, Karl-Fisher (KF) titration, pH and Appearance testing
- Review and follow methods, protocols, and SOPs in accordance with GXP guidelines while presenting methods and supporting data to senior management
- Perform dose analysis on diverse pharmaceutical drug samples like small molecules, large molecules, and oligonucleotides to optimize their outcomes
- Proficient in using Empower3, Chromeleon 7.2, LabX, Analyst, and LIMS systems
- Conducting data reviews, peer reviews, and studying archival materials
- Writing scientific reports, posters, and a monthly department newsletter
- Maintain process compliance integrity by adhering to SOPs and current good manufacturing practices (cGMP).
GRADUATE RESEARCH ASSISTANT
Texas A&M University-College Station
College Station , TX
2021.01 - 2023.05
- Conducted High-performance Liquid Chromatography (HPLC), Ultra Performance Liquid Chromatography (UPLC), Gas Chromatography-Mass Spectrometry (GCMS), Dynamic Light Scattering (DLS), Fourier Transform Infrared Spectroscopy (FTIR), and UV-visible spectrophotometry analyses
- Performed method development, validation and troubleshooting on mass spectrometers
- Conducted data analysis and review using JMP, R-software, Empower3, and Chromeleon 7.2
- Performed PCR, ddPCR, and DNA/RNA extraction adhering to EPA and FDA protocols.
INTERN ( R&D/ QA)
The Valdez Corporation
Dallas , TX
2022.06 - 2022.08
- Supported R&D by assisting with new research projects, conducting titration experiments, and verifying analyzed data in accordance with GLP and cGMP guidelines
- Inspected and produced COAs for targeted products, composed conclusive reports, and delivered presentations
- Utilized effective techniques for sample preparation and experiment design in sensory evaluation
- Ensured adherence to industry standards by implementing HACCP protocols and OSHA guidelines in the manufacturing facility
- Managed the process of sampling, holding, and releasing raw materials
- Carried out routine sample collection for allergen and antimicrobial testing on a weekly basis
- Maintained accurate and up-to-date nutritional data in Genesis software
- Analyzed current information and scholarly articles concerning the raw materials utilized in the manufacturing plant
- Facilitated learning and knowledge transfer to newly hired personnel at a manufacturing site
- Developed innovative spice blend formulations for various research and development initiatives.
INTERN
Government of Nepal
Pokhara , Gandaki
2018.11 - 2019.04
- Assisted in routine research, investigations, and special projects to support work of Prime Minister Agriculture Modernization Project
- Assisted with event planning, support and execution of virtual and in-person engagements for farmers training
- Conducted research on the effects of hormone applications on cucumbers in the field of plant pathology
- Collaborated in the mushroom seed production unit, aiding with farmer training
- Conducted data analysis using R programming and generated weekly reports and presentations.
Education
Master of Science - Food Sciences and Technology
Texas A&M University
05.2023
Bachelor of Science - Horticulture Science
Tribhuwan University
04.2019
High School Diploma -
SOS Herman Gmeiner
04.2014
Skills
- Method Development and Validation
- Compatibility and Stability studies, toxicology studies, protein analysis
- Dose analysis of pharmaceutical drugs
- Analytical instrumental skills (HPLC, GC-MS/ FID, LCMS, UV-Vis spectrophotometry, SoloVPE, and Karl Fisher)
- Writing and reviewing protocol, methods, and SOPs
- Data analysis, interpretation, and review
- Leadership and effective teamwork
Certification
- Advanced HPLC Method Development Using Quality by Design
- HPLC and UHPLC Troubleshooting: A Performance Qualification Approach
- Principles of HPLC Validation
- Practical HPLC for Biopharmaceuticals
- Fundamentals of HPLC
- GC-MS for Operators and Developers
- Intermediate Gas Chromatography
- Introduction to Gas Chromatography
- LC-MS/MS for Chromatographers
- Hazard Analysis and Critical Control Point (HACCP) certified
Leadership Experience
- Excellence in Leadership Chair, Institute of Food Technologists Student Chapter (IFTSA) |2022-2023|
- Department Representative at Women in Science and Engineering (WISE), Department of Food Science and Technology, Texas A&M University |2021-2023|
- President at Student Action Group of Horticulture (SAGH), Nepal |2016-2018|
- Secretary at Junior Red Cross Society, Nepal |2012-2014|
Manuscript In Preparation
- Characterization and Antimicrobial Activity of Carvacrol-loaded Nanoemulsion
- Cinnamaldehyde nanoemulsion: Properties, antimicrobial activity, and potential application as a washing treatment for spinach
Languages
- English, Full Professional
- Hindi, Professional
- Nepali, Native/ Bilingual
Awards
- Employee Hang 10 award and Employee High Five Award for excellent teamwork, critical thinking and early contribution to the Department of Biochemistry, Eurofins
- Student Travel Award 2021-2022, Texas A&M University (IFT FIRST2022)
- Nepalese Agricultural Professionals of Americas (NAPA) Mini-Grant Awardee-2019
- National Young Scientist Award-2019: Silver medal in the Theme Agriculture and Forestry
Publications
- Natural Essential Oils Stabilized with Soy Lecithin Control Selected Food-borne Pathogens, IFT FIRST 2022, July 10-11, Chicago, IL
- Management of root knot nematode (Meloidogyne spp.) in tomato, Association of Nepalese Agricultural Professionals of Americas (NAPA) Sponsored Research Mini-Grant Projects Conference, July11-12, 2020
Timeline
SCIENTIST II
Eurofins BioPharma Product Testing
2023.08 - Current
INTERN ( R&D/ QA)
The Valdez Corporation
2022.06 - 2022.08
GRADUATE RESEARCH ASSISTANT
Texas A&M University-College Station
2021.01 - 2023.05
INTERN
Government of Nepal
2018.11 - 2019.04
Master of Science - Food Sciences and Technology
Texas A&M University
Bachelor of Science - Horticulture Science
Tribhuwan University
High School Diploma -
SOS Herman Gmeiner
- Advanced HPLC Method Development Using Quality by Design
- HPLC and UHPLC Troubleshooting: A Performance Qualification Approach
- Principles of HPLC Validation
- Practical HPLC for Biopharmaceuticals
- Fundamentals of HPLC
- GC-MS for Operators and Developers
- Intermediate Gas Chromatography
- Introduction to Gas Chromatography
- LC-MS/MS for Chromatographers
- Hazard Analysis and Critical Control Point (HACCP) certified
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