Bhoomi Dholariya
Queens,NY
Summary
Dedicated Ph.D. student in Industrial Pharmacy with strong expertise in advanced drug delivery systems and nanomedicine. My research focuses on formulating next-generation therapeutics, including oncoprotein-targeted molecules, PROTACs, and tumor-suppressor genes, using platforms such as hydrophobic ion-pairing, ionizable lipid nanoparticles, and rapidly dissolving microneedles. I have hands-on experience designing genetic therapeutic formulations, including TP53 CRISPR and Elephant p53, and have presented my work at major scientific meetings such as AACR. My broader scientific goal is to create translational, clinically relevant delivery systems that improve bioavailability, druggability, and therapeutic efficacy for cancer treatment. I am committed to contributing meaningful innovations to the field of pharmaceutical sciences and advancing the development of next-generation anticancer therapies.
Overview
4
4
years of professional experience
1
1
Certification
Work History
Health Care Assistant
Ashton Lodge Residential care home
09.2022 - 03.2023
Intern
Halewood Laboratories Private Limited
03.2019 - 06.2019
Summer Trainee – Food and Pharmaceutical Manufacturing
Completed 5-week training
- Gained hands-on experience in manufacturing processes within food and pharmaceutical divisions.
- Learned key regulatory requirements and industry standards governing pharmaceutical production.
- Developed practical skills in quality assurance and quality control for multiple medicine batches.
- Acquired exposure to an industrial manufacturing environment, strengthening technical and operational competencies.
Education
PhD candidate - Industrial Pharmacy
St. John’s University
Queens, NY, USA11.2025
Master of Science - MSc Pharmacology With Project Management
University of Bedfordshire
Luton, UK01.2023
Bachelor of Pharmacy (B. Pharm) - Pharmacy
CHARUSAT University
Gujarat, India04.2020
Skills
- Carrying out techniques used at genetic level such as CRISPR/Cas9, transfection Good at performing SDS-PAGE, Gel electrophoresis, Western-blotting (wet-transfer), handling plasmid for digestion and cloning Proficient with Microsoft Office and many software’s used in Analytical and Comparative genomics like UV, HPLC, Benchling, Ensemble, Tide, Blast etc
- Accomplished experience of “Manipulation of DNA” via isolation of plasmid from Ecoli bacteria and performed digestion of same plasmid by targeting restriction sites on it
- Experienced and good understanding of Gel-purification, plating of bacteria, isolation of DNA, extraction of colonies, refreshing and handling of cell lines, PCR
- Experienced with 3D and 2D cell culture assay Multicellular tumor spheroid and MTT assay, Crystal violet assay, Clonogenic assay, Invasion assay, Cellular uptake assay respectively
Certification
American Association of Pharmaceutical Scientists. (AAPS) Annual Meeting
- Presenter and Attendee, 2024 & 2025
Timeline
Health Care Assistant
Ashton Lodge Residential care home
09.2022 - 03.2023
Intern
Halewood Laboratories Private Limited
03.2019 - 06.2019
PhD candidate - Industrial Pharmacy
St. John’s University
Master of Science - MSc Pharmacology With Project Management
University of Bedfordshire
Bachelor of Pharmacy (B. Pharm) - Pharmacy
CHARUSAT University
PUBLICATIONS
- Dholariya, Bhoomi, et al. "Idasanutlin-ionizable lipid nanocomplex for enhanced solubility, stability, and anticancer activity in p53 sensitive lung cancer." Colloids and Surfaces B: Biointerfaces (2025): 115058.
- Rathod, Drishti, et al. "KRAS mutation-driven enhanced macropinocytosis: using albumin as a trojan horse for delivering nanomedicine." Nanomedicine (2025): 1-15.
- Dholariya, Bhoomi, et al. "Developing a formulation of MDM2 inhibitor: Idasanutlin for enhanced stability, solubility, and anticancer activity in p53 sensitive lung cancer." Cancer Research 85.8_Supplement_1 (2025): 1849-1849.
- Dholariya, Bhoomi, et al. "Development of Elephant TP53 loaded lipoidic nanoparticles for the treatment of non-small cell lung cancer and colon cancer." Cancer Research 85.8_Supplement_1 (2025): 5699-5699.
RESEARCH WORKS
Master of Science – Pharmacology Research Project
Worked on a CRISPR/Cas9-based project using the MCF7 breast cancer cell line. The research, titled “Targeting Frameshift Mutations in the TP53 Gene via CRISPR/Cas9 in MCF7 Cells,” involved designing gene-editing strategies, performing supporting molecular techniques, and analyzing experimental outcomes. The project concluded with meaningful and well-supported findings.
Master of Science – Cell and Molecular Biology Research Proposal
Developed and submitted an independent research proposal titled “A Possible Cure for CARD14-Associated Generalized Pustular Psoriasis via CRISPR-Cas13a.” The proposal introduced a novel concept to correct CARD14 mutations using CRISPR-Cas13a, with the goal of validating the mutation’s role in disease pathology and exploring a potential therapeutic approach.