Designed and fabricated high-density flexible multi-electrode arrays for both in vitro and in vivo electrophysiology recording, stimulation, and electrochemical sensing
Developed flexible carbon nanomaterial-based multi-electrode arrays for in vivo electrochemical sensing and electrophysiology recording
Investigated conducting polymer nanocomposite coatings for electrochemical sensors, electrophysiology recording, and controlled drug delivery in vivo
Explored zwitterionic polymer coatings for seamless neural device integration in vivo
Conducted cell culture assays for material testing and performed rodent animal surgeries and behavior experiments.
Undergraduate Researcher
University of Pittsburgh
03.2016 - 07.2017
Developed polymer coatings for multi-electrode array devices and tested these devices for neural recording in rodents.
PEDOT/CNT flexible MEAs reveal new insights into the Clock gene's role in dopamine dynamics, B Wu, E Castagnola, CA McClung, XT Cui, Advanced Science, 2024
Fully flexible high-density implantable neural probes for electrophysiology recording and controlled neurochemical modulation, MH Malekoshoaraie
B Wu
DD Krahe, Z Ahmed, S Pupa, V Jain, M Chamanzar, XT Cui, Microsystems & Nanoengineering, 2024
Zwitterionic Polymer Coating Suppresses Microglial Encapsulation to Neural Implants In Vitro and In Vivo, Q Yang
JR Eles, AL Vazquez, TDY Kozai, XT Cui, Advanced biology, 2020
Facile synthesis of a 3, 4-ethylenedioxythiophene (EDOT) derivative for ease of biofunctionalization of the conducting polymer PEDOT, B Wu, B Cao, IM Taylor, K Woeppel, XT Cui, Frontiers in Chemistry, 2019
Zwitterionic Polymer Coated and Aptamer Functionalized Flexible Micro-Electrode Arrays for In Vivo Cocaine Sensing and Electrophysiology, B Wu, E Castagnola, XT Cui, Micromachines, 2023
Zwitterionic polymer/polydopamine coating reduce acute inflammatory tissue responses to neural implants, A Golabchi, B Wu, B Cao, CJ Bettinger, XT Cui, Biomaterials, 2019
Melatonin improves quality and longevity of chronic neural recording, A Golabchi, B Wu, X Li, DL Carlisle, TDY Kozai, RM Friedlander, XT Cui, Biomaterials, 2018
Flexible Glassy Carbon Multielectrode Array for In Vivo Multisite Detection of Tonic and Phasic Dopamine Concentrations, E Castagnola, EM Robbins, B Wu, MY Pwint, R Garg, T Cohen-Karni, XT Cui, Biosensors, 2022
Stable in-vivo electrochemical sensing of tonic serotonin levels using PEDOT/CNT-coated glassy carbon flexible microelectrode arrays, E Castagnola, EM Robbins, DD Krahe, B Wu, MY Pwint, Q Cao, XT Cui, Biosensors and Bioelectronics, 2023
Recent Advances in In Vivo Neurochemical Monitoring, C Tan, EM Robbins, B Wu, XT Cui, Micromachines, 2021
Batch Fabrication of Microelectrode Arrays with Glassy Carbon Microelectrodes and Interconnections for Neurochemical Sensing: Promises and Challenges, EA Faul, AM Broussard, DR Rivera, MY Pwint, B Wu, Q Cao, D Bailey, XT Cui, E Castagnola, Micromachines, 2024
Novel Polymer Coating for Improving Tissue Integration of Neural Interfacing Device, MRS 2019, Boston, MA, 12/01/2019, 12/06/2019
Flexible Micro Electrode Array (MEA) with carbon materials enabled stable in vivo dopamine detection, NEBEC 2021 (Virtual), 03/31/2021, 04/01/2021
Integrated Electrochemical and Electrophysiological In Vivo Micro Electrode Arrays with Zwitterionic Polymer Coating, MRS 2021 (Virtual), 04/17/2021, 04/23/2021
Multimodality multielectrode arrays for in vivo high density electrophysiology recording, controlled drug delivery, and neurochemical sensing, GRC Neuroelectronic Interfaces 2022, Ventura, CA, 2022
PEDOT/CNT flexible MEAs reveal new insights into the Clock gene's role in dopamine dynamics, GRC Neuroelectronic Interfaces 2024, Galveston, TX, 2024
Research
Graduate Research Assistant, University of Pittsburgh, Pittsburgh, PA, Dr. Tracy X. Cui, 08/2017, Present, Designed and fabricated high-density flexible multi-electrode arrays for both in vitro and in vivo electrophysiology recording, stimulation, and electrochemical sensing., Developed flexible carbon nanomaterial-based multi-electrode arrays for in vivo electrochemical sensing and electrophysiology recording., Investigated conducting polymer nanocomposite coatings for electrochemical sensors, electrophysiology recording, and controlled drug delivery in vivo., Explored zwitterionic polymer coatings for seamless neural device integration in vivo., Conducted cell culture assays for material testing and performed rodent animal surgeries and behavior experiments.
Undergraduate Researcher, University of Pittsburgh, Pittsburgh, PA, Dr. Tracy X. Cui, 03/2016, 07/2017, Developed polymer coatings for multi-electrode array devices and tested these devices for neural recording in rodents.
Awards
PPG paints, American Fortune 500. Summer scholarship, 2017
Department of Bioengineering. Bevier Award. University of Pittsburgh, 2018
Accomplishments
PPG paints, American Fortune 500. Summer scholarship. (2017)
Department of Bioengineering. Bevier Award. University of Pittsburgh. (2018)