Bowen Tang
Stockholm,Sweden
Summary
Ph.D. candidate in Epidemiology and Biostatistics specializing in pharmacoepidemiology and genetic epidemiology. Expertise in utilizing cohort, real-world, and genetic/multi-omics data to analyze drug effects and epidemiological outcomes. Demonstrated success in advanced study design, complex data analysis, and effectively communicating research findings to diverse audiences. Career ambitions include contributing to innovative medical care solutions through rigorous research methodologies.
Overview
4
4
years of professional experience
Work History
PhD Program: Repurposing Drugs for Aging and Alzheimer’s Disease
Karolinska Institutet
11.2020 - Current
- Company Overview: Karolinska Institutet, Sweden, and National Institutes of Health, US
- Led a Mendelian randomization study investigating the potential of antidiabetic drugs to lower Alzheimer’s disease risk using genetic data from UK Biobank and other datasets
- Conducted a target trial emulation study with Swedish register data to assess the effects of GLP-1 analogues, DPP-4 inhibitors, and sulfonylureas on dementia risk in T2DM patients
- Directed two longitudinal studies on medication effects on aging biomarkers in Swedish and US aging cohorts, developing within-individual analyses to capture biomarker changes over time
- Published three high-impact papers, presented findings at four conferences, and prepared press releases for public dissemination
- Led in study design, statistical analysis, and manuscript preparation
- Karolinska Institutet, Sweden, and National Institutes of Health, US
Investigating the Interaction Between Risk Genes and Occupational Inhalable Agents for Rheumatoid Arthritis Risk
Karolinska Institutet
02.2021 - 12.2022
- Company Overview: Karolinska Institutet, Sweden
- Designed and implemented a study assessing the interaction between genetic risk and occupational inhalable agents on rheumatoid arthritis risk, leveraging data from a case-control study
- Managed large datasets and led data visualization, contributing to an influential publication in a top rheumatology journal
- Karolinska Institutet, Sweden
Relationships Between Cardiometabolic, Psychiatric, and Autoimmune Diseases – Mendelian Randomization Studies
Karolinska Institutet
- Company Overview: Karolinska Institutet, Sweden
- Conducted studies exploring bidirectional relationships between obesity-related traits and RA, as well as type 2 diabetes and cardiometabolic disorders, leading to two publications in high-impact journals
- Developed comprehensive knowledge of cardiometabolic diseases and their connections to other diseases
- Karolinska Institutet, Sweden
Education
Ph.D. - Epidemiology and Biostatistics
Karolinska Institutet
Sweden01.2025
Master - Epidemiology
Karolinska Institutet
Sweden01.2020
Bachelor of Medicine -
Wuhan University
01.2018
Skills
- Epidemiological Research Design (cross-sectional study, case-control study, cohort study, longitudinal study, real-world evidence research)
- Biostatistical Analysis (linear regression, logistic regression, survival analysis, propensity score methods, causal inference techniques)
- Genetic Epidemiology (experience with biobank-scale datasets, GWAS, multi-omics data integration, Mendelian randomization, polygenic risk score, gene-environment interaction)
- Programming: R (five years), Unix (basic), SQL (basic), high-performance computing (basic)
Selectedpublications
- Tang B, Wang Y, Jiang X, Thambisetty M, Ferrucci L, Johnell K, et al. Genetic variation in targets of antidiabetic drugs and Alzheimer disease risk: a Mendelian randomization study. Neurology. 2022;99(7):e650-e9.
- Tang B, Liu Q, Ilar A, Wiebert P, Hägg S, Padyukov L, et al. Occupational inhalable agents constitute major risk factors for rheumatoid arthritis, particularly in the context of genetic predisposition and smoking. Annals of the Rheumatic Diseases. 2023;82(3):316-23.
- Tang B, Yuan S, Xiong Y, He Q, Larsson SC. Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study. Diabetologia. 2020;63:1305-11.
- Tang B, Shi H, Alfredsson L, Klareskog L, Padyukov L, Jiang X. Obesity‐related traits and the development of rheumatoid arthritis: evidence from genetic data. Arthritis & Rheumatology. 2021;73(2):203-11.
- Tang B, Meng W, Hägg S, Burgess S, Jiang X. Reciprocal interaction between depression and pain: results from a comprehensive bidirectional Mendelian randomization study and functional annotation analysis. Pain. 2022;163(1):e40.
- Tang B, Sjölander A, Wastesson JW, Maura G, Blotiere P-O, Szilcz M, et al. Comparative effectiveness of glucagon-like peptide-1 agonists, dipeptidyl peptidase-4 inhibitors, and sulfonylureas on the risk of dementia in older individuals with type 2 diabetes in Sweden: an emulated trial study. eClinicalMedicine. 2024;73.
- Tang B, Li X, Wang Y, Sjölander A, Johnell K, Thambisetty M, et al. Longitudinal associations between use of antihypertensive, antidiabetic, and lipid-lowering medications and biological aging. GeroScience. 2023:1-14.
Timeline
Investigating the Interaction Between Risk Genes and Occupational Inhalable Agents for Rheumatoid Arthritis Risk
Karolinska Institutet
02.2021 - 12.2022
PhD Program: Repurposing Drugs for Aging and Alzheimer’s Disease
Karolinska Institutet
11.2020 - Current
Relationships Between Cardiometabolic, Psychiatric, and Autoimmune Diseases – Mendelian Randomization Studies
Karolinska Institutet
Ph.D. - Epidemiology and Biostatistics
Karolinska Institutet
Master - Epidemiology
Karolinska Institutet
Bachelor of Medicine -
Wuhan University
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