Brian Nazaire
Tewksbury,MA
Summary
Dynamic QC Scientist II with expertise in qPCR and ddPCR, ensuring compliance and accuracy in analytical testing. Proven leader fostering a collaborative culture, skilled in SOP revision and cGMP practices. Committed to continuous learning and operational excellence, enhancing laboratory efficiency and data integrity.
Overview
8
8
years of professional experience
Work History
QC Scientist II
Pfizer
11.2023 - 06.2025
- Performed analytical testing for release and stability samples using qPCR (quantitative PCR) and ddPCR (digital droplet PCR) to ensure accuracy, reproducibility, and compliance with regulatory standards.
- Conducted scheduled maintenance, calibration, and troubleshooting of Applied Biosystems 7500 Real-Time PCR system, ensuring optimal instrument performance and minimizing downtime.
- Reported, reviewed, and tracked assay data through LIMS (Laboratory Information Management System) to maintain accurate and traceable records
- Authored, revised, and submitted Standard Operating Procedures (SOPs), contributing to streamlined workflows and compliance with GMP/GLP requirements.
- Validation and stability studies of DS/DP samples.
- 5S and safety committee representative in laboratory setting.
Technical Associate, Clinical Manufacturing
Pfizer
03.2022 - 11.2023
- cGMP production of phase I/II clinical drug substance for Pfizer Biotherapeutics portfolio
- Contributed to successful Small scale mRNA and saRNA campaigns
- Solo VPE, pH meter, and UV Spectrophotometer use and maintenance
- Comfortability working in Bio Safety Cabinets for extensive hours for final filtration and drug substance sampling.
- Experience working with purification techniques such as UFDF, Chromatography, tangential flow filtration and final filtration for downstream process
- Experience in Upstream bioprocessing such as microorganism isolation and selection, inoculum development, media preparation, inoculation, incubation, and harvest
- Safety Committee representative focused on preventative measures within GMP processing suites
- Contributed to large scale molecule campaigns such as ChoMAb, IL4/13 TSLP, IL4/33.
Manufacturing Quality Technician
Lantheus Medical Imaging
01.2021 - 03.2022
- Performed material transfer, preparation, batching, filling, inspection and ancillary operations associated with manufacturing of pharmaceutical products
- Entered, checked and reviewed data for accuracy and completeness, independently
- Demonstrated knowledge and fundamental understanding of operating computer-controlled automated production equipment
- Performed inventory moves and material transactions within ERP system
- Communicated effectively with Quality Control groups and Microbiology departments
- Coordinated procurement of various materials from warehouse needed for manufacturing processes
- Operated manufacturing equipment to validate protocols or engineering studies
Contractor
Randstad At Lantheus Medical Imaging Site
07.2020 - 01.2021
- Actively demonstrated Lantheus values of Accountability, Quality, Efficiency, Customer Service, and Safety
- Performed material transfer, preparation, batching, filling, inspection and ancillary operations associated with manufacturing of pharmaceutical products
- Demonstrated ability to apply cGMP Regulations to routine situations
- Demonstrated ability to receive directions and coaching from team lead and manager
Direct Care Staff
Department Of Industrial Services,
06.2017 - 03.2020
- Focused on career planning and crisis intervention for individuals with disabilities
- Tracked development and helped devise plans for further progressions
- Maintained data integrity and document accountability
Education
Bachelor of Science - Biology
University of Massachusetts Amherst
Amherst, MA05.2020
Skills
- Aseptic techniques under bio safety cabinet
- Pipetting contamination prevention
- SOP revision
- Group leader who seeks build a culture that promotes focused work environments where colleagues feel seen and understood so everyone can perform at their best
- Decision making and communicating to rest of team
- Knowledgeable in Good Manufacturing Procedures (cGMP), OSHA, and Standard Operating Operations (SOPs)
- Operating in Clean Room environment for 10 hours
- Excellent Verbal / Written Communication Skills in team settings
- Lifelong Learner
Additional Information
References: Provided upon request.
Timeline
QC Scientist II
Pfizer
11.2023 - 06.2025
Technical Associate, Clinical Manufacturing
Pfizer
03.2022 - 11.2023
Manufacturing Quality Technician
Lantheus Medical Imaging
01.2021 - 03.2022
Contractor
Randstad At Lantheus Medical Imaging Site
07.2020 - 01.2021
Direct Care Staff
Department Of Industrial Services,
06.2017 - 03.2020
Bachelor of Science - Biology
University of Massachusetts Amherst
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