BRITTANY WORTHAM
UNC School of Medicine
Durham,NC
6
years of professional experience
Clinical research professional prepared to leverage extensive background in managing clinical trials and research operations. Adept at ensuring compliance with regulatory standards and enhancing study efficiency. Known for fostering collaborative team environments and flexibly adapting to changing needs. Skilled in patient management and protocol development.
Work History
Sr. Clinical Research Coordinator
2 Years 5 Months- Led the planning, organization, conduct, and evaluation of multifaceted clinical research protocols, which included study execution, developing strategies and solutions to enhance study processes, and mentoring team members while reviewing their work.
- Coordinated study start-up activities, including IRB submissions, regulatory binders, and protocol amendments.
- Managed participant recruitment, screening, and informed consent processes across multiple clinical studies.
- Oversaw visit scheduling, specimen collection, and source documentation for protocol compliance.
Clinical Research Coordinator
1 Year 3 Months- Managed primary coordination duties for eight studies involving COVID, HIV, and pneumonia, overseeing informed consent, data collection, CRF completion, and participant visit reconciliation.
- Engaged in the initiation, execution, and conclusion of COVID and HIV Phase 2-4 clinical studies, while supporting IRB and regulatory obligations through recruitment material preparation and document management.
- Coordinated as backup for seven studies, ensuring leadership continuity and performing phlebotomy tasks during absences.
- Facilitated study visits by managing participant care, conducting necessary procedures, and organizing monitoring activities.
- Supported financial tasks for three study start-ups with OnCore, ClinCard, and EPIC databases, applying data analysis techniques to inform study decisions.
Research Analyst I
6 Months- Conducted investigations to plan, develop, and execute experimental procedures, enhancing clinical research trial operations in cryopreservation, leukopheresis, and rt-PCR.
- Analyzed materials using specialized laboratory techniques, preparing reports and monitoring trends to support informed conclusions.
- Created Standard Operating Procedures (SOPs) for laboratory management and testing protocols, standardizing processes for COVID and HIV research.
- Led the redevelopment of the Laboratory Data Management System (LDMS) overseeing thousands of HIV plasma productions stored in -80 freezers.
Research Technician II
1 Year 3 Months- Conducted assays and evaluated virus-specific responses related to HIV, processed human specimens for Sars-COV-2 virological testing using rt-PCR, and supported clinical research trials for Duke's faculty, staff, and students.
- Ensured laboratory safety and quality standards in compliance with Good Clinical Laboratory Practices (GCLP).
- Developed and refined testing protocols for senior management, improving efficiency and effectiveness of testing procedures.
Lab Technologist/PCR Scientist
7 Months- Facilitated testing of Sars-COV-2 samples from Duke Hospital and surrounding Durham population, contributing to clinical research efforts.
- Conducted Covid-19 rapid tests using accurate swabbing techniques for reliable specimen collection.
- Implemented stringent quality control measures and recorded patient data for accurate specimen preparation, testing, and analysis.
Molecular Lab Technician
5 Months- Performed rt-PCR tests during rapid escalation of Sars-COV-2 transmission, supporting clinical research initiatives.
- Managed reception and processing of test samples, executing DNA/RNA extraction, quantification, and gel quality control assessments in adherence to standardized operating procedures (SOPs).
- Executed qPCR, cleanup procedures, DNA sequencing, and data analysis, while utilizing a Laboratory Information Management System (LIMS) to manage Sars-COV-2 patient data and test outcomes efficiently.
- Trained new staff in diverse laboratory methodologies and maintained equipment crucial for Sars-COV-2 testing.
Education
Master of Science - Medical Physiology and Pharmacology
Bachelor of Science - Biology and Chemistry
Public Health Leadership Certificate - Public Health
Skills
Clinical Protocols
Clinical Monitoring
Protocol Development
EDC systems
Microsoft applications
CLIA/CAP Guidelines
GCP
Phlebotomy
Informed consent process
BLS/CPR Certified
Clinical trial management
Clinical data management
Accomplishments
Member of the RCAC (Research Coordinator Advisory Committee) at UNC Chapel Hill. Focused on bettering the recruitment and retention of research studies at UNC Chapel Hill.
Timeline
Sr. Clinical Research Coordinator
UNC School of Medicine
05.2024 - CurrentRead More
Clinical Research Coordinator
Wake Forest Baptist Health
02.2023 - 05.2024Read More
Research Analyst I
Duke Human Vaccine Institute
08.2022 - 02.2023Read More
Research Technician II
Duke Human Vaccine Institute
05.2021 - 08.2022Read More
Lab Technologist/PCR Scientist
Duke Human Vaccine Institute
10.2020 - 05.2021Read More
Molecular Lab Technician
Make Medical Laboratories
05.2020 - 10.2020Read More
University of Florida
Master of Science from Medical Physiology and Pharmacology
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Campbell University
Bachelor of Science from Biology and Chemistry
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UNC Chapel Hill
Public Health Leadership Certificate from Public Health
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Publication Acknowledgement
Metformin and Time to Sustained Recovery in Adults With COVID-19: The ACTIV-6 Randomized Clinical Trial, 2025