Summary
Overview
Work History
Education
Skills
Certification
Laboratory Skills
Submitted Abstracts And Publications
Submitted Grants
Honors And Awards
Laboratory Research Experience
Timeline
Generic

BRYAN J. HORRIGAN

Round Lake Beach

Summary

Thorough Senior Analyst with over a 10-year background in the Pharmaceutical industry across different functions including R&D Finance, R&D Clinical Pharmacology, and Clinical Operations . Excellent planning, organizational and communication skills. Self-reliant to perform analysis and make data driven recommendations. Talented in financial forecasting and data analysis.

Overview

16
16
years of professional experience
1
1
Certification

Work History

Forecasting Senior Analyst - Oncology

AbbVie
12.2022 - Current

-Conduct financial analyses to forecast financial Last Best Estimates (LBE) on clinical studies across the oncology platform.

-Forecast cost to conduct clinical studies based on gathered historical data to assist in portfolio planning.

-Gathers data from a variety of sources and provides quality clinical study budget information and metrics to Clinical and Finance Leadership to aid in planning decisions.

-Supports business operations in assessing and investigating actual study spend via SAP data vs. forecasted cost.


Study Management Associate III- Oncology

AbbVie
08.2021 - 12.2022

-Oversee clinical operations for a global oncology clinical study.

-Management of clinical study related activities including study start up activities.

-Management of vendors contributing critical aspects of clinical studies including central labs and central imaging vendors.

-Identify and resolve study related issues and inefficiencies.

-Facilitate study wide communications to internal cross functional teams and external stakeholders.

Associate Clinical Scientist - Oncology

AbbVie
01.2018 - 08.2021

-Analyze Phase I/II/III oncology data for large and small molecule therapeutics and generate figures, tables, and data visualization for presentation to senior scientific leadership.

-Analysis of study safety data and protocol deviations for disclosure in FDA required clinical study reports.

-Author phase I clinical study reports, population pharmacokinetic reports, exposure-response, exposure-safety and pharmacogenomic reports for FDA and global regulatory submissions.

-Prepare scientific posters for various conferences and presentations.

-Contribute in production of scientific manuscripts for journal submission.

-Experience with therapeutics for both solid and hematological cancers.

Clinical Study Associate

AbbVie
01.2015 - 09.2016

-Management of 175 global study sites and associated staff.

-Responsible for phase I- IV clinical studies.

-Management of trial master file (Veeva eTMF) in preparation of FDA audits.

-Ensuring compliance of clinical studies.

Senior Clinical Project Coordinator

Quintiles/IQVIA
06.2014 - 01.2015

-Liason between the clinical central laboratory, project management, and clients.

-Expedite patient data availability to clients for urgent clinical studies.

-Oversee input and accuracy of clinical data for clients.

Graduate Student / Cancer Researcher

LUC Stritch School of Medicine
07.2011 - 06.2014

-Tumor Immunology research assessing the use of tumor reactive T Cell Receptors in adoptive gene therapy using immunological and molecular biology based assays.

-Development of immunotherapies for use in the clinic for a variety of cancers and other pathologies.

-Generation of data from individually conducted research.

-Presentation of data to professionals within cancer research field, but also other outside of the field.

Clinical Trial Intern- Oncology

Loyola University Medical Center
06.2013 - 06.2014

-Preparation of Serious Adverse Events reports for IRB and FDA submission.

-Collaboration with principal investigators at Loyola for initiation of phase I oncology trials.

-Entry of clinical trial data for oncology studies.

Undergraduate Researcher

University of Minnesota
06.2010 - 09.2010
  • Exploration of potential biomarkers in saliva to be used clinically for a non-invasive method for early detection of oral cancers
  • Analysis of saliva proteins by mass spectrometry for differences in protein expression

Undergraduate Researcher

Plymouth State University
01.2009 - 01.2010
  • Characterize genes and biochemical pathways associated with production of Domoic Acid by marine diatom Pseudo-nitzschia multiseries

Education

MBA -

Loyola University Chicago Quinlan School of Business
Chicago, Illinois
08-2017

Master of Science - Molecular Pharmacology and Therapeutics

Loyola University Chicago School of Medicine
Maywood, Illinois
12.2016

Bachelor of Science - Biotechnology

Plymouth State University
Plymouth, New Hampshire
06.2011

Skills

-Clinical Study Financial Forecasting

-Data Analytics

-Quantitative Analysis

-Advanced Mathematics

-Microsoft Excel

-Microsoft PowerPoint

-Data Visualization and Presentation

-Tableau

-R

-SAP

-Clinical Study Operations

-Vendor Management

-Cross Functional Team Work

-Molecular Oncology

-Cancer Biology

-Immunology

-Molecular biology

-Biochemistry

-Tumor immunology

-Immunotherapy

Certification

  • Collaborative Institutional Training Initiative (CITI)
  • Good Clinical Practice (GCP FDA Focus)
  • Health Information Privacy and Security (HIPS)
  • Biomedical Research Conduct for Human Subjects
  • Responsible Conduct of Biomedical Research
  • IACUC Animal Model Training
  • Radioisotope Safety and Handling Training

Laboratory Skills

Viral Transduction, Transient Transfection, DNA and RNA Extraction, Gene Expression Analysis via qRT-PCR, PCR, Western Blot, Gel Electrophoresis, Multi-Color Flow Cytometry (FlowJo analysis), Cytokine Quantification (ELISA, Intracellular cytokine staining via Flow Cytometry), FACS based Cytotoxicity assays, Effector/Target co-culture assays, Fluorescence activated Cell Sorting (FACS), Magnetic activated cell sorting (MACS), Adherent and non-adherent cell culture and cell line maintenance, Lymphocyte extraction from whole blood or buffy coat via Ficoll gradient centrifugation, In vitro Primary lymphocyte expansion culture, Extraction of spleens from mice, Familiar with variety of mouse models and uses in research

Submitted Abstracts And Publications

  • Evaluating the potential of a novel oral lesion exudate collection method coupled with mass spectrometry-based proteomics for oral cancer biomarker discovery., Kooren JA, Rhodus NL, Tang C, Jagtap PD, Horrigan BJ, Griffin TJ, Clinical Proteomics, 2011
  • Evaluating sampling methods for improved salivary biomarker discovery via proteomics., BJ Horrigan, TJ Griffin, 2010
  • Natural Killer Cells Expressing Exogenous T-Cell Receptor Elicits Immunoreactive Response against Tumor Antigens., BJ Horrigan, Jehad Charo, 2012
  • Natural Killer Cells Expressing Tumor Specific T-Cell Receptors for Immunotherapy., BJ Horrigan, Jehad Charo, 2013

Submitted Grants

Tumor-specific T-Cell receptor expressing natural killer cells for immunotherapy., National Institute of Health (NIH), F31 Pre-doctoral Grant

Honors And Awards

  • Loyola University Chicago Academic Scholarship, 2011-2013
  • Plymouth State University Men's Varsity Ice Hockey Team, 2007-2011
  • Michelle Morse Book Scholarship, 2011
  • Plymouth State Men's Hockey Academic Achievement Recipient, Awarded annually to the individual graduating with the highest cumulative GPA., 2011
  • Plymouth State University Athletic Director Academic Honor Roll, 2010-2011
  • Massachusetts State Colleges Athletic Conference All Academic Team, 2010-2011
  • Participant of the National Student exchange, Spring 2010
  • Plymouth State University Textbook Scholarship Recipient, Fall 2010
  • Plymouth State University President's List, Fall 2009
  • Plymouth State University Dean's List, Fall 2008, Spring 2009
  • ECAC Northeast All Academic Team, 2008-2009

Laboratory Research Experience

  • Graduate Student / Cancer Researcher, Loyola University Chicago Stritch School of Medicine, Dr. Michael Nishimura, Dr. Jehad Charo, 2011-2014, Tumor Immunology research assessing the use of tumor reactive T Cell Receptors in adoptive gene therapy using immunological and molecular biology based assays., Development of immunotherapies for use in the clinic for a variety of cancers and other pathologies., Generation of data from individually conducted research., Presentation of data to professionals within cancer research field, but also other outside of the field.
  • Undergraduate Researcher, University of Minnesota, Dr. Timothy Griffin, Summer 2010, Exploration of potential biomarkers in saliva to be used clinically for a non-invasive method for early detection of oral cancers., Analysis of saliva proteins by mass spectrometry for differences in protein expression.
  • Undergraduate Researcher, Plymouth State University, Dr. Katie Rose Boissonneault, 2009-2010, Characterize genes and biochemical pathways associated with production of Domoic Acid by marine diatom Pseudo-nitzschia multiseries.

Timeline

Forecasting Senior Analyst - Oncology

AbbVie
12.2022 - Current

Study Management Associate III- Oncology

AbbVie
08.2021 - 12.2022

Associate Clinical Scientist - Oncology

AbbVie
01.2018 - 08.2021

Clinical Study Associate

AbbVie
01.2015 - 09.2016

Senior Clinical Project Coordinator

Quintiles/IQVIA
06.2014 - 01.2015

Clinical Trial Intern- Oncology

Loyola University Medical Center
06.2013 - 06.2014

Graduate Student / Cancer Researcher

LUC Stritch School of Medicine
07.2011 - 06.2014

Undergraduate Researcher

University of Minnesota
06.2010 - 09.2010

Undergraduate Researcher

Plymouth State University
01.2009 - 01.2010

MBA -

Loyola University Chicago Quinlan School of Business

Master of Science - Molecular Pharmacology and Therapeutics

Loyola University Chicago School of Medicine

Bachelor of Science - Biotechnology

Plymouth State University
BRYAN J. HORRIGAN