Summary
Overview
Work History
Education
Skills
Websites
Presentations
Accomplishments
Strengths
Languages
Timeline
Generic

Cheng Zhang

Summary

Experienced Senior Research Scientist with a wealth of expertise in molecular and cell biology. Demonstrating a robust skill set, I am proficient in modern molecular and cellular biology techniques such as CRISPR, shRNA, Western blot, flow cytometry, and cellular phenotype interrogation. Additionally, I'm experienced in drug discovery and cancer immunotherapy. As a committed advocate for team growth and continuous learning, I foster a culture of excellence, leveraging superior organizational and analytical skills to thrive in fast-paced environments. With exceptional communication and presentation abilities, I am fluent in both English and Mandarin, ensuring seamless collaboration and dissemination of research findings.

Overview

14
14
years of professional experience

Work History

Senior Research Associate

UT Southwestern Medical Center
01.2022 - Current
  • Designed and conducted independent research to explore molecular mechanisms in cancer and identify potential therapeutic targets for cancer treatment.
  • Directed, guided and delegated tasks to teams and developed project schedules, resource requirements and timelines to maintain productivity on goals and objectives.
  • Achieved project objectives by troubleshooting experiments and testing practical and creative solutions.
  • Collaborated with colleagues and other peer investigators on on various projects within a fast-paced laboratory setting.
  • Collaborated with my supervisor on grant writing, contributing to the successful acquisition of an RO1 grant.
  • Authored 14 peer reviewed publications in high impact scientific journals.
  • Showcased research findings at international symposiums.

Post-Doctoral Fellow

UT Southwestern Medical Center
12.2019 - 01.2022
  • Conducted self-directed research to investigate the signaling regulation underlying cancer and find potential therapeutic targets for cancer treatment.
  • Collaborated with colleagues to gather research and publish findings.
  • Developed and implemented RIPseq protocols and analysis procedures within the laboratory setting.
  • Collaborated with colleagues to expand and maintain collections of whole human ORF library.
  • Assisted teaching and instructing students alongside PI.
  • Authored 7 professional scientific papers for publishing in peer-reviewed journals.

Post-Doctoral Fellow

Lewis Katz School of Medicine at Tempe University
01.2016 - 12.2019
  • Managed research projects that aimed to determine the regulating signaling in vascular inflammation, autophagy, and hyperglycemia-induced vascular disorders, which resulted in a postdoctoral fellowship award.
  • Generated various transgenic mouse models.
  • Enforced laboratory safety protocols and enabled safe work environment.
  • In charge of laboratory management including new employee training, lab inventory maintenance, lab protocol amendment and renewal, animal protocol writing and revision
  • Troubleshot and developed experimental tools to deal with ever-evolving technology.
  • Presented research at multiple conferences to share primary findings with fellow researchers and faculty members.

Graduate students

Zhejiang University
09.2010 - 12.2015
  • Lead a project to study molecular mechanism in ciliogenesis and embryo development, which resulted in a co-first authored publication in a leading scientific journal
  • Collaborated with other peers to study the molecular mechanism of colorectal and gastric tumorigenesis
  • Trained and taught new students with immunohistochemistry, fluorescent microscopy, or immunoassays.
  • Worked in fluorescent core to assist other students on confocal machines.

Education

Ph.D. - Cell Biology

Zhejiang University
Zhejiang, China
12.2015

Bachelor of Science - Biotechnology

Shandong Agriculture University
Taian, China
06.2010

Skills

  • Crispr-cas9 gene editing
  • Virus Vectors engineering & packaging (LV/AAV)
  • Immunoassay (ELISA, WB, IF & IHC, etc)
  • Electroporation, nucleofection, lipofection and virus infection
  • Protein engineering, expression & purification
  • Next generation sequencing (NSG)
  • Flow cytometry
  • Confocal/electronic microscopy
  • Primary & mammalian cell culture
  • Project design, scientific writing, data analysis & interpretation
  • Transgenic mouse model
  • Excellent organization, problem-solving & time management
  • Literature review
  • Mentoring & leadership

Presentations

  • 2023, Von Hippel Lindau (VHL) tumor suppressor regulates m6A-dependent gene expression involved in renal tumorigenesis, AACR Advances in Kidney Cancer, Austin, USA
  • 2018, Nogo-B regulates hyperglycemia induced endothelial dysfunction by modulating mitochondria function, ATVB/PVD 2018 Scientific Sessions, San Francisco, USA
  • 2016, Nogo-B controls inflammation by regulating autophagy in macrophage, 4th Annual Temple Translational Science Symposium, Philadelphia, USA

Accomplishments

  • Published Researcher
  • Published 26 peer reviewed papers in hing impact journals, cited over 680 times.

  • Research Grant Recipient
  • Successfully secured a research grant of $106,532.00 from the American Heart Association (AHA).

  • Young Investigator Award
  • CAAC-ATVB Metabolic Vascular Disease Symposium, USA, 2018

  • Excellent Scholarship
  • Zhejiang University School of Medicine, China, 2017



Strengths

  • Research Skills

Conduct extensive research in molecular cell biology, with proficiency in both in vitro molecular or cell-based experiments and in vivo mouse-based experiments. Leading to 30+ publications.

  • Communication

Strong ability to communicate and showcase complex biological concepts to audient of varying levels of understanding.

  • Collaboration

With extensive experience collaborating with numerous colleagues on diverse projects, I bring forth excellent organizational skills and meticulous attention to detail, ensuring the best outcomes are achieved.

Languages

English
Professional Working
Chinese (Mandarin)
Native or Bilingual

Timeline

Senior Research Associate

UT Southwestern Medical Center
01.2022 - Current

Post-Doctoral Fellow

UT Southwestern Medical Center
12.2019 - 01.2022

Post-Doctoral Fellow

Lewis Katz School of Medicine at Tempe University
01.2016 - 12.2019

Graduate students

Zhejiang University
09.2010 - 12.2015

Ph.D. - Cell Biology

Zhejiang University

Bachelor of Science - Biotechnology

Shandong Agriculture University
Cheng Zhang