Accomplished organic and synthetic chemist with expertise in small molecule process development and peptide synthesis. Led cross-functional teams in optimizing API synthesis, ensuring high-purity production and successful customer collaborations.
Overview
15
15
years of professional experience
Work History
Sr. Process Scientist
SK Pharmteco
Rancho Cordova, California
04.2024 - Current
Led project chemist supporting step chemists and analytical method development (AMD) team to ensure project progress.
Identified and established a resupply site for over 100 kg production, facilitating future multi-100 kg capabilities.
successfully delivered the target material to the customer with a higher purity and higher quantity
Provided technical support to the engineering team during daily discussions on plant production, including MBR and key step processes.
Acted as control tower during campaign, maintaining close communication with customer.
Process Scientist III
AMPAC Fine Chemicals
Rancho Cordova, CA
08.2020 - Current
Executed R&D process optimization for API synthesis, transitioning from lab scale to plant-ready.
Key member of a multidisciplinary team (QA, QC, and engineers) that completed a multi-million dollars validation campaign for the scale-up synthesis of a promising IND currently undergoing clinical trials.
Coordinates with engineers & operators for the supervision of the scale-up operations in the plant.
Participates in the review of Master Batch Records (MBR) for process transfer from lab to the plant.
Collaborated with customers to address and resolve issues related to scale-up process.
Visiting Scientist
SK Pharmteco
Daejeon, S. Korea
02.2026 - 04.2026
Led peptide project at Rancho site, coordinating efforts to ensure timely delivery of project milestones.
Participated in customer call to identify and resolve current peptide issue, enhancing client satisfaction.
successfully completed CSBio and manual SPPS synthesis technology transfer
Observed peptide synthesis processes at SK biotek in Korea to gain insights for improving methodologies.
Post-doctoral Research Associate
Northeastern University
Boston
09.2016 - 07.2020
Small molecule synthesis for antibacterial and antimalarial drug discovery.
Manage lab chemical inventory system and supply (chemical) order.
Provided assistance to undergraduate and graduate students in their academic pursuits.
Post-doctoral Research Associate
Kyushu University
Fukuoka, Japan
01.2011 - 03.2016
Conducted research on asymmetric aerobic oxidation with chiral salen complexes in a laboratory setting.
Performed asymmetric aziridination experiments utilizing Ru-salen complex as a catalyst in organic synthesis.
Conducted advanced research in molecular biology and genetics.
Collaborated with faculty on interdisciplinary projects and grant proposals.
Analyzed experimental data using statistical software and bioinformatics tools.
2nd place oral presentation at USF chemistry department annual symposium
Government scholarship (Rok)
Publications
Shotgun Kinetic Target-Guided Synthesis Approach Enables the Discovery of Small-Molecule Inhibitors against Pathogenic Free-Living Amoeba Glucokinases, Kassu, M., Parvatkar, P.T., Milanes, J., Monaghan, N.P., Kim, C., Dowgiallo, M., Zhao, Y., Asakawa, A.H., Huang, L., Wagner, A., Miller, B., Carter, K., Barrett, K.F., Tillery, L.M., Barrett, L.K., Phan, I.Q., Subramanian, S., Myler, P.J., Van Voorhis, W.C., Leahy, J.W., Rice, C.A., Kyle, D.E., Morris, J., Manetsch, R., ACS Infect. Dis., 2023, https://pubs.acs.org/doi/10.1021/acsinfecdis.3c00284
Pyrazole‐Thiazole core‐containing analogs exhibit adjunctive activity with meropenem against carbapenem‐resistant enterobacteriaceae (CRE)., Kim, C.; Kassu, M.; Smith, K. P.; Kirby, J. E.; Manetsch, R., ChemMedChem, 2021, https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cmdc.202100321
Unnatural amino acid receptor incorporation as a novel photoaffinity tool for gpcr heteromer signaling studies., Winn, B. T.; Kim, C.; Cui, M.; Manetsch, R.; Logothetis, D. E., Biophys. J., 2020, 118, 3, 95a-96a, https://www.sciencedirect.com/science/article/pii/S0006349519316121?via%3Dihub
Ruthenium-catalyzed cross-selective asymmetric oxidative coupling of arenols., H Hayashi, T Ueno, C Kim, T Uchida, Org. letters, 22, 4, 1469-1474, https://scholar.google.com/citations?view_op=view_citation&hl=en&user=NyL8vBwAAAAJ&sortby=pubdate&citation_for_view=NyL8vBwAAAAJ:YsrPvlHIBpEC
Iron-Catalyzed Asymmetric Inter- and Intramolecular Aerobic Oxidative Dearomatizing Spirocyclozation of 2-Naphthols., T Oguma, D Doiuchi, C Fujitomo, C Kim, H Hayashi, T Uchida, T Katsuki, Asian J. Org. Chem., 9, 404-415, https://scholar.google.com/citations?view_op=view_citation&hl=en&user=NyL8vBwAAAAJ&sortby=pubdate&citation_for_view=NyL8vBwAAAAJ:WAzi4Gm8nLoC
A Whole-Cell Screen for Adjunctive and Direct Antimicrobials Active Against Carbapenem-Resistant Enterobacteriaceae., Smith; K P; Dowgiallo, M D; Chiaraviglio, L; Parvatkar, P; Kim, C; Manetsch, R; Kirby, J E., SLAS Discov., 2019, 24, 8, 842-853, https://journals.sagepub.com/doi/full/10.1177/2472555219859592?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
Personal Information
Title: Process Scientist
Leadership Experience
Project step lead (2+ years) for current fast-track clinical drug.
Weekly project presentation to customer.
Oversight undergraduate and graduate student.
Support graduate student a basic organic chemistry set up.
Group organizer at Sacramento Korean Table Tennis.
Scientist II Downstream process transfer (Team lead) at VJ Biosciences Pvt LtdScientist II Downstream process transfer (Team lead) at VJ Biosciences Pvt Ltd