Danielle Camastra

· Independently Manage and treat common oncologic medical problems including infusion/transfusion reactions, hypersensitivity reactions related to chemotherapeutic agents, neutropenic fevers, immune mediated reactions, fluid overload, Pneumonias, URI's, bronchitis, sinusitis, UTI's, stomatitis, anxiety and depression.

• · Management of chronic medical conditions that are exacerbated by chemotherapeutic agents such as (but not limited to) hypertension, hypo/hypernatremia, electrolyte disarray, diabetes mellitus, obesity, chronic pain syndromes, thyroid disease, liver dysfunction, neuropathy, sleep disorders, malnutrition.
• · Procedures: I and D's; wound and skin care, injections, aseptic and isolation techniques, venipuncture, initiation of intravenous infusions, CPR, placement of catheters
• · Participate in monthly Grand Rounds, Joint Oncology Hematology Department Division Meetings, align with continuous medical education through frequent CMEs and journal readings, member of ASCO.
• · Work well with entirety of nursing and medical staff in Oncology Infusion Center as well as UNC Hospital
• · Proficient in EPIC database
• · Cover COVID Vaccine clinic reactions; assess and treat any and all COVID vaccine reactions in timely fashion. Observe and interpret common reactions, document and report as indicated.

• Clinician who functions as primary care provider, functioning autonomously with expertise in health conditions and management of health related conditions.
• Focus on improving patient’s quality of life for health plan members through effective care coordination.
• Travel to patient’s home to perform home health assessments
• Capture an accurate picture of member’s health including all current, chronic and historical conditions
• Identify gaps in care and assisting to develop a plan to manage their health
• Uncover clinical and social determinants that contribute to the management of the members health
• Evaluate results of questions asked, explain, perform and interpret various lab and screening tests
• Analyze potential contraindications regarding medications and interactions with OTC and supplements
• Ability to determine diagnoses based on supportive evidence
• Identify risk factors that may exist and how this may impact their current health and need for further referral to the health plans’ case management, PCP or notifying adult protective services
• Perform physical exam, perform PAD testing, Spirometry testing, hgb A1C POC testing

• Primary care provider in a community health center with a focus on preventative medicine.
• Involved in all aspects of patient care across the lifespan, including; detailed history, physical examinations, development and implementation of treatment plans, medication management, ordering and interpretation of laboratory tests.
• Participated in a community based program to teach nutrition and offer health & wellness coaching with SMART goals for free to those patients interested in making measurable and sustainable changes to their health.
• · Use motivational interviewing to assess readiness for change. Utilize a myriad of coaching techniques to focus on the patient goals and desires
• · Extensive practice in the area of adolescent and adult medicine including personal care and nutrition, disorders, the effective management of ADHD, and eating disorders
• · The ability to focus on mental health as it effects physiological well being.

• Primary in-patient surgical Physician Assistant on the Hepatobiliary service.
• Manage all complicated pre-, peri-, and post-operative pancreatic resection and liver resection patients.
• Round independently and with the surgical team, make assessments, plans for each patient.
• Communicate daily with the current resident and Attending Surgeon to discuss care plans and status of each patient.
• Educate and assist service interns and senior trainees in evaluating and managing post-operative care.
• Obtain consults, collaborate with multiple teams and act as inpatient champion for ERAS (Early Recovery After Surgery), DEFT (Duke Elder & Family Care), POSH (Perioperative Optimization of Senior Health) and Duke Perioperative Pain Care team to assist in post operative optimization and opioid titration.
• Tract and monitor pertinent information in ACP NSQIP database
• Proficient in Maestro systems, familiar with Electronic Health Record Systems; Duke MyChart
• Reduced post op Opioid Induced Constipation by using adjuvant analgesics and non opioid modalities
• Decreased post op related UTIs by over 50% by using designated careplan and removing foley catheters POD 1
• Decreased Length of Stay of post op Pancreatic resection patients by over 1 day during time periods of 2014-2017
• Decreased Hepatobiliary Service Re-Admission Rate by 51% in 2016

• Work directly with Internal Medicine Attendings in the Attending Hospitalist Service.
• Care for adult patients with a wide variety of illnesses and disease, acutely ill and chronically sick, typically admitted through the Emergency Department.
• Work as a valued member of a patient’s health care team, take medical histories, exam and treat patients, order and interpret lab results, prescribe medications and discharge patients.

• Integral founding member of well-established, highly respected PA-run inpatient transplant program. Round daily with multidisciplinary team, assist attending Hepatologist, Gastroenterologist, and Transplant Surgeons in the care of pre- peri and post operative transplant and hepatobiliary patients.
• Provide direct patient care for surgically and complex medically ill patients and newly transitioned pediatric patient on a Step Down Unit and floor unit
• Perform physical exams, conduct diagnostic and therapeutic procedures such as; large volume therapeutic & diagnostic abdominal paracentesis; bedside I & D, wound care management; wound VACs placement, removal, dressing change; chest tube removal, IR placed intra-abdominal & thoracic pig tail catheter removal; JP drain removal, blood culture and tissue culture collection, ABGs, phlebotomy for trough values, CPR, and ACLS
• Independently titrate immunosuppression and teach fellows and residents how to appropriately dose and titrate immunosuppression
• Train and oversee new Transplant Surgical Fellows, PA hires and surgical residents
• Proficient in EPIC computer systems
• Titrate all blood sugars due to newly steroid induced diabetes mellitis for all transplant patients
• Dose anti fungal and antibacterial regimens appropriately given patients current organ function
• Consult and collaborate with Endocrinologist, Infectious Disease, Psychiatry, Interventional Radiology, PharmD, Social Work, Nutrition and ICU teams regularly
• Prescribe and educate patients and family on medications, immunosuppression and expected symptoms of rejection and infection risks
• Provide complete patient Discharge including education, DSUMs, records, follow up appointments, medications and education materials.

• Member of the Developmental Chemotherapy service research team and worked in compliance with all regulatory, institutional and Clinical Trials Department requirements.
• Attending weekly clinic practice to help facilitate protocol patient eligibility and enrollment.
• Explain protocol tests and procedures to patients, address protocol related questions, review ordered laboratory and radiologic tests for protocol purposes.
• help facilitate FDA approval of noval drug Arsenic Trioxide and experienced FDA approval in entirety
• assist in publications, manuscripts, ASCO Abstracts, EORTC NCI annual meeting Abstracts and ASH Annual meeting abstracts

• R. Wieder, S. Novick, B. Hollis, M. Bryan, S. Chanel, K. Owusu, D. Camastra, T. Saunders, L. Pliner, J. Harrison, P. Bonate, T. Williams, and S. Soignet. “Pharmacokinetics and Safety of ILX23-7553, a Noncalcemic-Vitamin D3 Analogue, in a Phase I Study of Patients with Advanced Malignancies”. Inves New Drugs. 2003 Nov:21(4): 445-52
• R. Wieder, S. Novick, B. Hollis, M. Bryan, S. Chanel, K. Owusu, D. Camastra, T. Saunders, L. Pliner, J. Harrison, P. Bonate, T. Williams, and S. Soignet. “Pharmacokinetics and Safety of ILX23-7553, a Noncalcemic-Vitamin D3 Analogue, in a Phase I Study of Patients with Advanced Malignancies”. (Abstract 2002 ASCO Annual Meeting)
• J. Dupont, D. Camastra, M.S. Gordon, et al. “A Phase I Study of VEGF Trap in Patients with Solid Tumors and Lymphoma.” Proc Am SocClinOncol. 2003;22:194.
• J. Dupont, D. Camastra, M.S. Gordon, D. Mendelson, J. Murren, A. Hsu, A. Lucarelli, J. Cedarbaum, D. Spriggs. “A Phase I Study of VEGF Trap in Patients with Solid Tumors and Lymphoma”. (Abstract 2003 ASCO Annual Meeting)
• J. Dupont, C. Aghajanian, P. Chapman, D. Dizon, J. Koutcher, L. Krug, R. Motzer, P. Sabbatini, L. Schwartz, S. Sharma, D. Camastra, S. Pezzulli, V. Ty, M. Gordon, J. Murren, A. Lucarelli, J. Cederbaum, D. Spriggs. “Early Findings in a Phase I Study of the Novel High Affinity VEGF Binder VEGF Trap in Patients with Refractory Solid Tumors and Lymphoma”. (Abstract 2002 European Organisation for Research and Treatment of Cancer [EORTC]-NCI Annual Meeting)
• S. Novick, S. Soignet, S. Chanel, T. Saunders, D. Camastra, T. Williams, and R. Wieder. “Phase I Study of Vitamin D3 Analogue ILX23-7553 in Patients with Advanced Malignancies”. (Abstract 2001 ASCO Annual Meeting)
• L.H. Camacho, J. Ryan, S. Chanel, P. Maslak, P. Salomoni, A. Jakubowski, V. Klimek, D. Camastra, S. Nimer, P.P. Pandolfi, and S.L. Soignet. “Transcription Modulation: A Pilot Study of Sodium Phenlybutyrate Plus 5-Azacytidine”. (Abstract 2001 The American Society of Hematology [ASH] Annual Meeting).