Summary
Overview
Work History
Education
Skills
Timeline
Generic

Danielle Szczygielski

Worcester,MA

Summary

Bioanalytical chemistry analyst with a strong track record in leading validation studies and developing analytical methods under regulatory guidelines. Demonstrates technical proficiency with LC-MS and HPLC operations, ensuring quality outcomes and fostering collaboration across teams to enhance research capabilities.

Overview

4
4
years of professional experience

Work History

Bioanalytical Chemistry Analyst III

Charles River Laboratories
Shrewsbury, MA
05.2025 - Current
  • Develop and conduct analytical method validation/qualification/transfer and study sample analysis according to protocol, SOPs, and regulatory guidance (GLP)
  • Led validation and sample analysis studies, coordinating sample scheduling and requests to ensure timely analysis.
  • Conducted complex oligonucleotide assays in laboratory settings
  • Collaborated with cross-functional teams, contributing to the successful execution of research and development projects.
  • Draft and revise laboratory methods, addendums, procedure templates and protocols

Bioanalytical Chemistry Analyst II

Charles River Laboratories
Shrewsbury, MA
09.2023 - 05.2025
  • Identified Q1 and Q3 masses and optimized assays on 5500 and 6500+ tandem mass spectrometers to improve analysis accuracy.
  • Guided multiple analysts on extraction procedures and HPLC/LC-MS data analysis, ensuring consistency in results.
  • Collaborated with scientists to develop and optimize experimental procedures.
  • Prepared samples for analysis following strict safety and quality guidelines.
  • Trained junior staff on equipment usage and safety practices, enhancing overall team competency.

Bioanalytical Chemistry Research Analyst I

Charles River Laboratories
Shrewsbury, MA
07.2022 - 09.2023
  • Operated and maintained LC/MS and automation instrumentation, performing troubleshooting on 5500, 6500, and 6500+ Mass Spectrometers.
  • Executed and documented experimental procedures, ensuring adherence to timelines and protocols.

Education

Master of Pharmacology and Toxicology -

Michigan State University
East Lansing, MI
05-2027

Bachelor of Arts and Science - Biology

University of South Carolina
Columbia, SC
01-2021

Skills

  • Analytical method validation
  • Oligonucleotide assays
  • HPLC operation
  • LC-MS operation
  • Mass spectrometry
  • Chromatography expertise
  • Sample analysis techniques
  • Method development
  • Solid-phase extraction
  • protein precipitation extraction
  • liquid liquid extraction
  • Instrument maintenance
  • Lab documentation
  • Analytical chemistry

Timeline

Bioanalytical Chemistry Analyst III

Charles River Laboratories
05.2025 - Current

Bioanalytical Chemistry Analyst II

Charles River Laboratories
09.2023 - 05.2025

Bioanalytical Chemistry Research Analyst I

Charles River Laboratories
07.2022 - 09.2023

Master of Pharmacology and Toxicology -

Michigan State University

Bachelor of Arts and Science - Biology

University of South Carolina
Danielle Szczygielski