Derek Crenshaw
Bay Area,CA
Summary
Detail-oriented manufacturing and operations professional with hands-on experience in biotechnology production, machine operation, and workplace safety. Proven ability to meet production targets, troubleshoot equipment, and maintain strict quality and OSHA compliance standards. Strong team player with experience training new employees and supporting efficient, safe production environments.
Overview
8
8
years of professional experience
Work History
Clerk
Contra Costa County
06.2025 - Current
- Maintained accurate records and documentation in a regulated government environment.
Cashier / Receptionist
Kaiser Permanente
10.2023 - 06.2025
- Processed transactions accurately while following organizational procedures.
Machine Operator
Kaneka Aerospace
04.2022 - 03.2023
- Complied with company and OSHA safety rules and regulations.
- Daily operations included training employees and proper processes to ensure a safe working environment and uphold company standard.
- Issue LOTO's to perform Safe maintenance operations.
- Operated and maintained a diverse selection of machinery to ensure optimal production efficiency.
- Followed detailed instructions to operate machines with accuracy and produce quality products.
- Coordinated workflow among team members to maximize output and reduce downtime.
- Trained new operators on equipment usage and safety protocols.
- Monitored and operated machine performance, troubleshooting issue's to minimize interruptions.
- Operated on new machines and implemented new processes and SOP's for production environment.
Manufacturing Technician
Sutro Biopharma
03.2020 - 04.2021
- Daily operations complied with safety requirements cGood Manufacturing Process (cGMP),
Standard Operating Procedures (SOP), Good Documentation Practices (GDP). - Executed and reviewed SOPs for upstream and downstream processes.
- Closely collaborated with Quality Control(QC) and Quality Assurance (QA) for proper FDA regulated documents and processes.
- Operated DCS systems, centrifuges, bioreactors, and protein harvesting equipment.
- Documented manufacturing activities, deviations, and batch records.
- Operations included use of LOTO's for safe machine maintenance.
- Use of PPE for operations.
- Operations includes use of cryogenic liquids for proper cell storage.
- Operations of large and small scale bioreactors.
- Work environment includes use of high pressures and temperatures for daily operations.
- Worked on validation of processes and equipment due to new facility.
- Operated with use of manual and automated valves.
- Sterile transfers of product to maintain purity's in spec.
- Performed equipment troubleshooting to minimize downtime.
Manufacturing Support / Equipment Prep Technician
Genentech
06.2018 - 03.2019
- Performed daily schedule checks and shift pass downs to ensure continuity of operations.
- Daily operations were focused maintaining safe environment and following FDA regulations.
- Use of Distributed control system (DCS), Human machine interface (HMI), System analysis programs (SAP), Manufacturing Execution System( MES) For day today operations.
- Verified equipment and room status; monitored in-process activities and completed end-of-run checks.
- Loaded and operated COP washers using validated parts per SOPs, following safety inspections and procedures.
- Assembled and disassembled Bioreactors using SOP's.
- Loaded and operated autoclaves.
- Tracked and restocked parts inventory using automated inventory management systems.
- Followed work orders and production requests to prepare manufacturing components including bioreactors, filters, and spinners.
- Communicated with internal customers regarding production needs and escalated issues to leads or supervisors as required.
Education
High school diploma -
Prospects High School
Antioch, CA06.2012
Skills
- Manufacturing & Production Operations
- Machine Operation & Maintenance
- Equipment Troubleshooting
- OSHA & Workplace Safety Compliance
- Use of cryogenics
- Implementation and use of safety
- DCS, SAP, MES, HMI, IP21
- Manual and Automated operation systems
- Quality Control & Documentation
- Team Collaboration & Training
Timeline
Clerk
Contra Costa County
06.2025 - Current
Cashier / Receptionist
Kaiser Permanente
10.2023 - 06.2025
Machine Operator
Kaneka Aerospace
04.2022 - 03.2023
Manufacturing Technician
Sutro Biopharma
03.2020 - 04.2021
Manufacturing Support / Equipment Prep Technician
Genentech
06.2018 - 03.2019
High school diploma -
Prospects High School