Devon Ehnes
Seattle,WA
Summary
Experienced senior scientist with a strong foundation in advanced research and academic scholarship. Proven track record of leading innovative projects in stem cell biology and regenerative medicine across multiple organ systems, resulting in numerous scholarly publications. Skilled in utilizing analytical techniques and collaborative research methodologies. Known for quick learning, effective communication, and valuable teamwork.
Overview
8
8
years of professional experience
Work History
Senior Postdoctoral Fellow
University of Washington
11.2019 - Current
- Laboratory of Dr. Hannele Ruohola-Baker, Institute for Stem Cells and Regenerative Medicine
- Conducted extensive research to contribute to scientific knowledge in stem cell and organoid research, resulting in 10 academic publications in peer-reviewed journals.
- Project 1: Molecular signatures controlling salivary gland development: studies toward organoid development
- Project 2: Adapting novel computer designed proteins to improve endothelial cell differentiation and maturation for in vivo regenerative vascular applications
- Conducted extensive research
- Enhanced research capabilities by employing advanced analytical techniques including bioinformatic analysis of large scale datasets.
- Enhanced research methodologies with innovative approaches and techniques.
- Mentored junior researchers and graduate students for skill development.
- Presented research findings at conferences to promote knowledge sharing.
Science Writer
Freelance
05.2018 - 10.2019
- Dissertation editing, scientific article and application note writing, data interpretation, literature reviews, copyediting
- Diverse clientele in the United States and abroad
- Utilized exceptional writing, editing, and proofreading skills to produce engaging and error-free content.
- Enhanced brand visibility by effectively converting data into easy-to-read application notes that highlighted product potential
Tutor
Freelance
04.2018 - 10.2019
- Provided one-on-one tutoring sessions for K-12 children, undergraduate, and postgraduate students, tailoring instruction to meet the specific needs of each student while promoting independent learning skills.
- Multiple subjects: at the primary/secondary school level, reading for both young children and adults, writing composition, penmanship, all levels of math, biology, chemistry, English language/literature, Spanish, and French. I worked as a college-level tutor of molecular, cellular, general, and cancer biology, and introductory and medical genetics.
- Increased student comprehension by utilizing personalized teaching methods and adapting to individual learning styles.
- Tutored diverse groups of students to strengthen subject comprehension, boost confidence, and build important learning skills.
Postdoctoral Scholar
University of Southern California
11.2016 - 06.2018
- Center for Craniofacial Molecular Biology, Laboratory of Dr. Yang Chai
- Project 1: Investigation of the role of Twist1 and Tcf12 in controlling cranial suture stem cell homeostasis in patients with Saethre-Chotzen syndrome
- Project 2: Investigation into the molecular role of the dura mater controlling cranial suture patency
- Collaborated with interdisciplinary teams to enhance research quality and foster innovation.
- Contributed to scholarly community by reviewing articles for academic journals.
Education
Ph.D. - Cell, Molecular, and Developmental Biology
University of California Riverside
Riverside, CA10.2016
Bachelor of Science - Biology, Minor in French
University of California Riverside
Riverside, CA06.2010
Skills
- Adult/Embryonic Stem Cells
- Mammalian Cell Lines
- Primary cells
- Organ culture
- Organoid Development
- Survival surgeries
- Embryo manipulation
- Timed Breeding
- Transgenic Lines
- CRISPR Gene editing
- Western blotting
- Co-immunoprecipitation
- Flow cytometry & live cell sorting
- Single cell/Bulk RNA Sequencing
- RT-PCR & Real-time quantitative PCR
- Tissue sectioning (frozen & paraffin)
- Immunoassays
Cell Culture & Differentiation
Animal Husbandry & In vivo Studies
Gene & Protein Expression Analysis
- In situ hybridization
- RNA Scope and SABER-FISH
- Histochemical assays
- Bacterial cell culture & transformation
- Phase Imaging
- Fluorescent and Confocal Imaging
- Magnetic Resonance Imaging
- Microsoft Office Suite
- Leica and Nikon Imaging Software
- Adobe Acrobat Pro & Photoshop
- Image J
- Biorender
- R Programming for bioinformatic analysis
- Research design
- Scientific writing
- Data analysis
- Literature review
Microscopy
Computer Skills
Project and Laboratory Management
Honors And Grants
- Ruth L. Kirschstein Interdisciplinary Research Training (T90) Postdoctoral Fellowship, 2020-2023
- Travel Award, Global Foundation for Peroxisomal Disorders, 2017
- NIDCR Diversity Research Supplement, 2017-2018
- Inland Empire Stem Cell Consortium Travel Award, ISSCR International Conference, Stockholm, Sweden, 2015
- MAC Travel Award, American Society for Cell Biology Conference, San Diego, CA, 2015
- Graduate Dean's Dissertation Research Grant, 2015
- Best Oral Presentation, Clinical Translation of Stem Cells Conference, 2014
- First Place, Inland Empire Stem Cell Consortium Poster Presentation, 2013
- Graduate Research Mentoring Program Fellowship, 2012-2013
- Omicron Delta Kappa National Leadership Honor Society, 2012
- Dean's Distinguished Fellowship, University of California-Riverside, 2010-2015
- Alliance for Graduate Education and the Professoriate (AGEP) Fellowship, 2010
- Chancellor's Honor List, 2009-2010
- Dean's List, 2009-2010
Publications
- Ehnes DD, Morishita A, Phal A, Jung HY, Lim YC, Vincent T Detraux D, Alghadeer A, Hanson-Drury S, Mathieu J, Cirulli V, Young J, Freidman B, Ruohola-Baker H. Development of human iPSC-derived salivary gland organoids guided by sci-Seq of human fetal tissue. In preparation.
- Zhao YT*, Ehnes DD*, Kumar S, Wang X, Litvicov P, Phal A, Hoffman C, Wu XW, Cooper J, Mathieu J, Baker D, Ruohola-Baker H. Computationally Designed Multivalent Tie2 Agonists Ameliorate Diabetic Vascular Instability Through Two Distinct Classes of Tie2 Complexes. In preparation.
- Edman NI*, Phal A*, Redler RL*, Schlichthaerle T*, Srivatsan SR, Ehnes DD, Etemadi A, Seong JA, Favor A, Li Z, Praetorius F, Gordon M, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H#, Baker D#. Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies. Cell, S0092-8674(24)00534-8
- Hanson-Drury S, Patni AP, Lee DL, Alghadeer A, Zhao YT, Ehnes DD, Vo VN, Kim SY Jithendra D, Phal A, Baker D, Young J, Ruohola-Baker H. (2023) Single cell RNA sequencing reveals human tooth type identity and guides in vitro hiPSC derived odontoblast differentiation (iOB). Frontiers in Dental Medicine, 4: 1209503.
- Alghadeer A, Hanson-Drury S, Patni AP, Ehnes DD, Zhao YT, Li Z, Phal A, Vincent T, Lim YC, O’Day D, Spurrell CH, Gogate AA, Zhang H, Arikketh D, Wang Y, Starita L, Doherty D, Glass IA, Shendure J, Freedman BS, Baker D, Regier M, Mathieu J, Ruohola-Baker H. (2023) Single-cell census of human tooth development enables generation of human enamel. Dev Cell 58(20):2163-2180.e9.
- Ehnes DD, Alghadeer A, Hansen-Drury S, Zhao YT, Tilmes G, Mathieu J#, Ruohola-Baker H#. (2022) Sci-Seq of human fetal salivary tissue introduces human transcriptional paradigms and a novel cell population. Frontiers in Dental Medicine, 3:887057.
- Ehnes DD*, Levy S*, Ruohola-Baker H. (2021) Epigenetics and Regenerative Medicine. Medical Epigenetics 2e. Chapter 29: 853-872.
- Somasundaram L*, Levy L*, Hussein AM, Ehnes DD, Mathieu J, and Ruohola-Baker H. (2020) Epigenetic metabolites license stem cell states. Current Topics in Developmental Biology, 138:209-240.
- Ehnes DD*, Hussein AM*, Ware CB, Mathieu J, Ruohola-Baker H. (2019) Combinatorial metabolism drives the naïve to primed chromatin landscape. Experimental Cell Research, 389(2):111913.
- Keller KC, Ding H, Tieu R, Sparks NR, Ehnes DD, Zur Nieden NI. (2016) Wnt5a supports osteogenic lineage decisions in embryonic stem cells. Stem Cells and Development, 25(13):1020-1032.
- Ehnes DD*, Gernasar RM*, Rancourt DE, zur Nieden NI. (2015). Exogenous Nitric Oxide Enhances Calcification of Stem Cell Derived Osteogenic Cultures. Differentiation 89(3-4): 97-103.
- Ehnes DD*, Price FD*, Shrive NG, Hart DA, Rancourt DE*, zur Nieden NI* (2015). Embryonic Stem Cell-Derived Osteogenic Cultures Are Capable of Responding to Mechanical Oscillatory Compression Stress. Journal of Biomechanics 48(10) :1915-1921.
- McClelland Descalzo DL*, Ehnes DD*, zur Nieden NI. (2014) Stem Cells for Osteodegenerative Diseases: Current Studies and Future Outlooks. Regenerative Medicine. Regenerative Medicine. 9(2), 219-230.
Languages
English
Native or Bilingual
Spanish
Native or Bilingual
French
Professional Working
Timeline
Senior Postdoctoral Fellow
University of Washington
11.2019 - Current
Science Writer
Freelance
05.2018 - 10.2019
Tutor
Freelance
04.2018 - 10.2019
Postdoctoral Scholar
University of Southern California
11.2016 - 06.2018
Ph.D. - Cell, Molecular, and Developmental Biology
University of California Riverside
Bachelor of Science - Biology, Minor in French
University of California Riverside
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