Dominic Martinelli
Ithaca,NY
Summary
Current student at Cornell University working towards a major in Biological Sciences with a concentration in Neurobiology and Behavior. Research interests include genetic medicine, neuropharmacology, and the application of computational tools for the discovery of novel therapeutics.
Overview
2
2
years of professional experience
Work History
Undergraduate Student Researcher
Cornell University
Ithaca, NY
01.2024 - Current
- Worked with Dr. Samuel Woodburn in the Kwan Lab (Meining School of Biomedical Engineering)
- Studied mechanism of action of psilocybin in infralimbic cortex in mouse models of PTSD
- Performed fluorescence microscopy to detect cortical structures related to therapeutic promise of psilocybin for psychiatric conditions
- Sectioned mouse brains and prepared slides for fluorescent imaging and histology
Academic Contractor
AgileOne
Indianapolis, IN
07.2022 - 08.2023
- Developed machine learning models and cheminformatics methods to support drug discovery at large pharmaceutical company.
- Applied data science techniques to predict drug metabolism and off-target effects.
- Designed workflows to integrate biophysical modeling with generative machine learning.
- Researched applications of informatics techniques to the development of gene therapies.
- Published one research article, submitted two additional articles for review, and presented research internally.
Education
Bachelor of Science - Biological Sciences, Biochemistry
Cornell University
Ithaca, NY05.2027
Skills
- Python
- R
- Computational Biology and Chemistry
- Research and Publication
- Data Science
Publications
- From sequences to therapeutics: Machine learning predicts chemically modified siRNA Activity (10.1016/j.ygeno.2024.110815)
- Machine learning for metabolomics research in drug discovery (10.1016/j.ibmed.2023.100101)
- Generative machine learning for de novo drug discovery: A systematic review (10.1016/j.compbiomed.2022.105403)
- In silico vaccine design: A tutorial in immunoinformatics (10.1016/j.health.2022.100044)
Timeline
Undergraduate Student Researcher
Cornell University
01.2024 - Current
Academic Contractor
AgileOne
07.2022 - 08.2023
Bachelor of Science - Biological Sciences, Biochemistry
Cornell University