Dominique Nguyen

A highly motivated regulatory scientist with a keen interest in research compliance seeking opportunities in clinical trials compliance and management of new devices,

Publications

• Youssef S., Nguyen D.T., Soulis T., Panagiotopoulos S., Jerums G., and Cooper M.E. Effect of diabetes and aminoguanidine therapy on renal advanced glycation end product binding. Kidney International, 55, 907-16, 1999.
• Nguyen D.T., Hernandez E., Vauzour D., Schonthal A.H., Rice-Evans C., Cadenas E. and Spencer J.P.E. The intracellular genistein metabolite 5,7,3¢,4¢-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in breast cancer cells via modulation of p38 signaling pathway Free Rad Biol & Med 15;41, 2006.:1225-39
• Goldman M.E., Cregar L., Nguyen D.T., Simo O., O’Malley S. and Humphreys T. Cationic polyamines inhibit anthrax lethal factor protease BMC Pharmacology 6:8, 2006

Abstracts

• Spencer J.P.E, Nguyen D.T., and Vasour D. Flavanoid regulation of cell cycle via interactions of MAP kinase and PI3 kinase/AKT kinase Oxidants and antioxidants in biology, Oxygen Club of California, 2006
• Goldman M., Cregar L., Nguyen D.T., Simo O., O’Malley S., Nagata M., Jiao G., Tang C. Discovery and characterization of nucleic acid-independent cationic inhibitors of anthrax lethal factor protease. Biomolecular Screening 2004
• Tang C., Simo O., Nagata M., Jiao G., O’Malley S., Goldman M., Cregar L., Nguyen D. and Hemscheidt Design, synthesis, and SAR of anthrax lethal factor protease inhibitor A261 Proceedings from the American Chemical Society, 2004
• Nguyen D.T., Garcia J.V., and Cadenas E. Genistein causes cell cycle arrest and apoptosis in T47D breast cancer cells. Oxidants and antioxidants in biology, Oxygen Club of California, 2002.
• Nguyen D.T., Garcia J.V., and Cadenas E. Genistein causes cell cycle arrest in T47D breast cancer cells. Free Radical Biology & Medicine, 2001
• Nguyen D.T., Garcia J.V., and Cadenas E. Genistein causes cell cycle arrest via inhibiton of p53-independent mechanisms in T47D breast cancer cells. Free Radical Biology and Medicine, 2000.
• Nguyen D.T., Sastra S., Panagiotopoulos S., Soulis T., Cooper M.E., and Jerums G. Parallel increases in fluorescent and immunoreactive advanced glycation end products in early diabetes. Australian Diabetes Society Proceedings, 1996.
• Nguyen D.T., Panagiotopoulos S., Soulis T., Cooper M.E., and Jerums G. Aminoguanidine and methylguanidine reduce mesenteric vascular enlargement in experimental diabetes. Diabetologia 38 Supplement I, A255, 1995.
• Sastra S., Soulis T., Panagiotopoulos S., Nguyen D.T., Cooper M.E., and Jerums G. Development of polyclonal antibody based elisa for advanced glycation end products. Australian Diabetes Society Proceedings, A89, 120, 1995.
• Nguyen D.T., Sastra S., Panagiotopoulos S., Soulis T., Cooper M.E., and Jerums G. Parallel increases in fluorescent and immunoreactive advanced glycation end products in early diabetes. Australian Diabetes Society Proceedings, 1996

• CITI training completed for ICH/GCP E6(r2) [Transcelerate Biopharma approved training]
• CITI Human Subjects Research, and IRB Chair & Administrator, Social & Behavioral Research
• Leadership development training (in progress)
• IACUC AALAS training
• Certified IRB Professional (CIP) eligible

• 2000-2003: Research and teaching assistant at the University of Southern California
• 1998-2000: Research assistant at the University of Texas at Austin
• 1997-1998: Research assistant at Texas A&M Medical School
• 1995-1997: Research and teaching assistant at the University of Melbourne

2000: Young Investigator’s Award, Oxygen Society, San Diego, California, USA

1998: College of Pharmacy Travel Grant, the University of Texas at Austin

1996: Australian Diabetes Travel Award

1996: European Association for the Study of Diabetes Award

1996: National Heart Foundation Young Investigator's Travel Award

1996: Australian Juvenile Diabetes Foundation Travel Award

1994-1996: Australian Postgraduate Award