DR. SK Abu Saleh

Dynamic Postdoctoral Fellow at the University of Minnesota, specializing in total synthesis of natural products and library design. Proven ability to mentor graduate students while driving innovative research in combating Gram-negative pathogens. Adept at chemical data analysis and fostering cross-functional collaborations, enhancing both academic and industry partnerships.

• Senior Research Fellowship (UGC-SRF), University Grants Commission (UGC), New Delhi, India, 01/21/19, 01/20/22
• Junior Research Fellowship (CSIR-JRF), University Grants Commission (UGC), New Delhi, India, 01/21/17, 01/20/19, 55

• Research experience in synthetic organic chemistry.
• Capacity in organic synthesis (from milligrams to multi-gram scale) and dry reactions (to handle super dry solvent and moisture-sensitive reagents).
• Design and synthesized a number of biologically important new methodology.
• Asymmetric synthesis of natural products and their applications.
• Bruker Avance III 300, 400, 500, 600 MHz NMR, Agilent Technologies HPLC (both chiral phase and reverse phase), GC-MS, LC-MS, TLC-MS.
• Experience in operating software like Sci-Finder, ChemDraw, Topspin, MestreNova, etc.
• Manage collaborative projects & communicate with scientists across various disciplines.
• Good laboratory management and handling skills.

(1) “Gram-negative Permeation Rules of the New Class of Gyrase Inhibitors” Adamiak, J. W.; Leus, I. V.; Bergen, C. R.; Walker, S. S.; Raheem, I. T.; Balibar, C. J.; Mesbahi-Vasey, S.; Saleh, S. A.; Duerfeldt, A. S.; Rybenkov, V. V.; Zgurskaya, H. I. (Manuscript Submitted).

(2) “Sequential Hydroperoxylation and Amberlyst-15 Catalyzed Hock-type Rearrangement of Spiroepoxy/Spiroaziridine Oxindoles for the Synthesis of 2-Hydroxybenzo[b][1,4]oxazin-3(4H)-ones” Saleh, S. A.;Mondal, A. S. M.; Senapati, S.; Hajra, S.* Asian J. Org. Chem. 2024, 13, No. e202300581.

(3) “Selective C3-Allylation and Formal [3+2]-Annulation of Spiro-aziridine Oxindoles: Synthesis of 5ʹ-Substituted Spiro[pyrrolidine-3,3′-oxindoles] and Coerulescine” Saleh, S. A.; Hazra, A.; Singh, M. S., Hajra, S.* J. Org. Chem. 2022, 87, 8656.

(4) “Regioselective Hydroperoxylation of Aziridines and Epoxides Only with Aqueous Hydrogen Peroxide” Saleh, S. A.; Hazra, A.; Hajra, S.* Adv. Synth. Catal. 2022, 364, 391.

(5) “Sequential one-pot synthesis of N-sulfonyl spiroaziridine oxindoles from spiroepoxy oxindole” Biswas, A.; Saleh, S. A.; Hazra, A.; Debnath, S. C.; Hajra, S.* Org. Biomol. Chem. 2021, 19, 5624-5631.

(6) “Aqueous tert-Butyl Hydroperoxide Mediated Regioselective Ring-Opening Reactions of Spiro-aziridine/-epoxy Oxindoles: Synthesis of 3-Peroxy-3-substituted Oxindoles and Their Acid-Mediated Rearrangement” Hajra, S.;* Hazra, A.#; Saleh, S. A.#; Mondal, A. S. Org. Lett. 2019, 21, 10154 (# equal contribution).

(7) “One Pot Synthesis of Enantiopure Spiro[3,4-dihydrobenzo[b][1,4]oxazine-2,3'-oxindole] via Regio- and Stereoselective Tandem Ring Opening/Cyclization of Spiroaziridine Oxindoles with Bromophenols” Hajra, S.;* Hazra, A.; Saleh, S. A. J. Org. Chem. 2019, 84, 10412.

(8) “Organocatalytic Domino Reaction of Spiroaziridine oxindoles and Malononitrile for the Enantiopure Synthesis of Spiro[dihydropyrrole-3,3′-oxindoles]” Hajra, S.;* Saleh, S. A.; Hazra, A.; Singh, M. S. J. Org. Chem. 2019, 84, 8194.

(9) “Domino Corey–Chaykovsky Reaction for One-Pot Access to Spirocyclopropyl Oxindoles” Hajra, S.;* Roy, S.; Saleh, S. A. Org. Lett. 2018, 20, 4540.

(10) “Catalyst-Free Ring Opening of Spiroaziridine Oxindoles by Heteronucleophiles: An Approach to the Synthesis of Enantiopure 3-Substituted Oxindoles” Hajra, S.;* Roy. S. M.; Biswas, A.; Saleh, S. A. J. Org. Chem. 2018, 83, 3633.

I hereby declare that the information given above is true to the best of my knowledge.

Date: 22. 01. 2026                                                                                                  (SK Abu Saleh)