Summary
Overview
Work History
Education
Skills
Certification
Publications and Presentations
Timeline
Generic

Dustin Lockney

Raleigh,NC

Summary

Biophysicist with ten (10) years of industrial experience and eight (8) years of academic experience. Highly skilled at understanding technical information and synthesizing solutions and strategic plans. Extensive experience with project management and presenting technical information to audiences with various backgrounds.

Overview

19
19
years of professional experience
1
1
Certification

Work History

Adjunct Professor Of Chemistry

Wake Technical Community College
Raleigh, NC
01.2020 - Current
  • Taught general chemistry, organic chemistry, and biochemistry.
  • Adapted course material to provide online instruction during the pandemic.

Scientist III

BioAgilytix
Durham, NC
08.2018 - 12.2019
  • Performed assay validation experiments for FDA approval of five (5) drug products.
  • Report writing.
  • Watson-LIMS to document changes during experiments, noting unexpected issues arising during research activities.
  • Provided statistical analysis of assays for customers using JMP (by SAS).

Scientist I

Meso Scale Discovery
Gaithersburg, MD
09.2014 - 07.2018
  • Prioritized project tasks after discussions with C-level department team.
  • Managed two research assistants to bring multiplexed immunoassay platforms to market.
  • Developed 25 research-grade immunoassay blood tests.
  • Created two poster presentations for sales team to market new products.
  • Weekly progress presentations. (~300 presentations)
  • Supported/Lead two customer projects.

Lead Scientist

NanoVector
Raleigh, NC
10.2012 - 06.2018
  • Managed two (2) scientists and three (3) research assistants to meet project deadlines.
  • Designed chemical formulations and characterization methods for anticancer plant virus nanoparticles.
  • Collaborated with scientists from Sartorious, Medicago, and other CROs to design scalable bioprocesses for manufacturing virus-like particles.
  • Collaborated with Zamboni Group at UNC-Chapel Hill, experts in PK/PD analysis of nanoparticle formulations, to design and perform in vivo studies on pre-clinical models.

Postdoctoral Research Scientist

North Carolina State University
Raleigh, NC
01.2012 - 08.2012
  • Designed five (5) high-throughput screening assays for detection of small molecule inhibition of therapeutically relevant miRNA; screened library of 5,000 small molecules for miRNA inhibition.
  • Proficient with NAMD (nanoscale molecular dynamics simulations) and AutoDock to design, and subsequently express enzymes with enhanced or modified activities.
  • Grant writing experience.

Research Assistant

North Carolina State University
Raleigh, NC
08.2006 - 12.2011
  • Mentored five (5) undergraduate students performing independent research.
  • Mentored four (4) study-abroad students in Poznan, Pl; photo-organic chemistry.
  • Taught physical chemistry recitation courses; four (4) semesters.
  • Taught general chemistry lab; one (1) semester.

Education

Ph.D. - Chemistry

North Carolina State University
Raleigh, NC
12.2011

Master of Science - Chemistry

Marshall University
Huntington, WV
06.2006

Bachelor of Science - Biology

University of Charleston
Charleston, WV
06.2002

Skills

  • Seven years of experience developing virus-like particles (VLPs) for in vivo targeted drug delivery
  • Four (4) years of project management experience
  • Contributing author to publications and proposals
  • Three (3) years of contract research experience and consulting for immunoassay development
  • Seven (7) certifications in programming (Python, SAS, and Google Analytics)
  • Biotechnology Experience: ten (10) years of new technology development
  • Fifteen (15) years of data analysis experience using various software packages (JMP, Origin, IGOR, Excel)

Certification

  • Design of Experiments (JMP by SAS) - 2022
  • Decision making with data (JMP by SAS) - 2022
  • Quality Methods (JMP by SAS) - 2022
  • Statistical Thinking and Problem Solving (JMP by SAS) - 2022
  • Diversity and Inclusion in Education - 2021
  • Python Data Structures - 2016EPIC Online Teaching Certification, Wake Technical Community College - 2020.
  • Doing More with SAS Programming, Coursera - 2019
  • Getting Started with SAS Programming, Coursera - 2019
  • Project Management: The Basics for Success, Coursera - 2018
  • Introduction to Genomic Technologies, Coursera - 2017
  • Data Management and Visualization, Coursera - 2016
  • Python Data Structures, Coursera - 2016
  • Programming for Everybody, Coursera - 2016

Publications and Presentations

PUBLICATIONS

  • Madden AJ.; Oberhardt B,; Lockney D.; Santos C.; Vennam P.; Arney D.; Franzen S.; Lommel SA.; Miller CR.; Gerhig P.; Zamboni WC., Pharmacokinetics and efficacy of doxorubicin loaded Plant Virus Nanoparticles in preclinical models of cancer. Nanomedicine 2017, 12 (20), 2519-2532.
  • Oberoi, P.; Suschak, J.; Stenglin, M.; Aghvanyan, A.; Nikolenko, G.; Roy, D.; Gardner, L.; Lockney, D.; Shukla, A.; Porter, E.; Miller, T.; Biesso, A.; Sardesai, L.; Sivakamasundar, R.; Mathew, A.; Glezer, E. N.; Wohlstadter, J. N., True Sensitivity of Immunoassays: Are Concentrations of Low Abundance Analytes Real or Artifacts? The Journal of Immunology 2016, 196 (1 Supplement), 138.9-138.9.
  • Lockney, D.; Franzen, S.; Lommel, S., Viruses as nanomaterials for drug delivery. Methods Mol Biol 2011, 726, 207-21.
  • Lockney, D. M.; Guenther, R. N.; Loo, L.; Overton, W.; Antonelli, R.; Clark, J.; Hu, M.; Luft, C.; Lommel, S. A.; Franzen, S., The Red clover necrotic mosaic virus capsid as a multifunctional cell targeting plant viral nanoparticle. Bioconjug Chem 2011, 22 (1), 67-73.
  • Wang, R.; Lockney, D. M.; Goshe, M. B.; Franzen, S., Mass spectrometric detection of targeting peptide bioconjugation to Red clover necrotic mosaic virus. Bioconjug Chem 2011, 22 (10), 1970-82.
  • Lockney, D.; Miksovská, J., Characterization of carbon monoxide photodissociation from Fe(II)LPO with photoacoustic calorimetry. J Phys Chem B 2006, 110 (47), 24165-70.

POSTERS AND PRESENTATIONS

  • Lockney, D.M., Suschak, J., Stengelin, M., Ranganathan, S., Butler, J., Davydov, I., Wohlstadter, J.N., Detection of fg/mL Levels of GM-CSF in Human Serum and Plasma. Poster presentation at 4th Meeting of the International Cytokines and Interferon Society 2016.
  • Hill, C., Lockney, D., Franzen, S., Lommel, S., “Elucidation of the Ca(II) dissociation constant of the Red clover necrotic mosaic virus capsid” American Society for Virology 30: 636-Virus structure and assembly. Minneapolis, MN, 2011. Poster.
  • Franzen, S., Lockney, D., Wang, R., Lommel, S., Hauck, M., “In vivo imaging and tumor targeting using a plant virus nanoparticle” Abstract of papers of the American Chemical Society 241: 48-COLL. Anaheim, CA, 2011. Presentation by second author.
  • Lockney, D., “Cell targeting by plant virus nanoparticles” Abstracts of papers of the American Chemical Society 238: 408-COLL. Washington, D.C., 2009. Presentation.
  • Lockney, D. and Miksovska, J., “Photophysical properties of acridine 9-carboxylic acid in aqueous solutions studied by photoacoustic calorimetry and photothermal beam deflection” Abstracts of Papers of the American Chemical Society 235: 386-PHYS. New Orleans, LA, 2008. Poster.
  • Lockney, D. and Miksovska, J., “Kinetic and thermodynamic study of CO-binding to lactoperoxidase using photoacoustic calorimetry and transient absorption” Abstracts of Papers of the American Chemical Society 230: 216-BIOL. Washington, D.C., 2005. Poster

Timeline

Adjunct Professor Of Chemistry

Wake Technical Community College
01.2020 - Current

Scientist III

BioAgilytix
08.2018 - 12.2019

Scientist I

Meso Scale Discovery
09.2014 - 07.2018

Lead Scientist

NanoVector
10.2012 - 06.2018

Postdoctoral Research Scientist

North Carolina State University
01.2012 - 08.2012

Research Assistant

North Carolina State University
08.2006 - 12.2011

Ph.D. - Chemistry

North Carolina State University

Master of Science - Chemistry

Marshall University

Bachelor of Science - Biology

University of Charleston
  • EPIC Online Teaching Certification, Wake Technical Community College - 2020.
  • Doing More with SAS Programming, Coursera - 2019
  • Getting Started with SAS Programming, Coursera - 2019
  • Project Management: The Basics for Success, Coursera - 2018
  • Introduction to Genomic Technologies, Coursera - 2017
  • Data Management and Visualization, Coursera - 2016
  • Python Data Structures, Coursera - 2016
  • Programming for Everybody, Coursera - 2016
Dustin Lockney