Ebony Shah Williams
Houston,TX
Summary
Skilled professional with a Doctor of Philosophy (Ph.D.) in Medical and Molecular Genetics and 10+ years of experience in providing expert insights into recruiting diverse populations into genomic clinical trials. Ensuring studies are conducted, recorded, and reported in accordance with the protocol, standard operating procedures (SOPs), ICH-GCP and CLIA standards. Monitor recruitment and the completion of data collection from multiple clinical sites. Performing lead data analyses from large clinical data sets, including the INGENIOUS pharmacogenetic and ECOG-ACRIN breast cancer clinical trial.
Overview
14
14
years of professional experience
Work History
Clinicial Genomic Scientist
HELIX
06.2023 - 02.2024
- Evaluated and implemented new technologies to improve quality and robustness of sample analysis.
- Contributed valuable insights during project planning meetings by presenting research findings and proposing innovative solutions to scientific challenges.
- Increased research efficiency by streamlining laboratory processes and implementing new technologies.
- Conducted extensive literature reviews to inform research direction and stay current on emerging trends.
- Work collaboratively across multiple teams to improve data flow and processes.
- Curation of hundreds of variants, genes, and gene-disease correlations following ACMG guidelines, using internal datasets and online resources.
- Interpretation and analyses of whole genome/exome sequencing data.
- Blurb writing for clinical report drafting.
- Meets productivity standards; completes work promptly; Strives to increase productivity; Works quickly while maintaining quality.
- Curate variants for hereditary cancer, cardiomyopathy, and population genomic screening.
- Analyze raw sequencing data via Integrated Genetic Viewer (IGV).
- Navigate genetic software and databases, i.e, varsome, UCSC, HGMD, mutation taster, mutation analyzer, etc.
Clinical Genomic Scientist
Baylor Genetics (Industry)
11.2021 - 06.2023
- Increased research efficiency by streamlining processes and implementing new technologies.
- Work collaboratively across multiple teams to improve data flow and processes.
- Curation of hundreds of variants, genes, and gene-disease correlations following ACMG guidelines, using a robust internal dataset and online resources.
- Interpretation and analyses of whole genome/exome sequencing data.
- Clinical report drafting.
- Curate variants for hereditary cancer, carrier, and prenatal screening.
- Analyze raw sequencing data via Integrated Genetic Viewer (IGV).
- Navigate genetic software and databases, i.e, Alamut, ClinVar, UCSC, Uniprot, and others.
PhD Medical & Molecular Genetics Student
Indiana University
08.2017 - 08.2021
- Responsible for designing and implementing research studies from the large Ingenious pharmacogenetic clinical trial and the ECOG-ACRIN breast cancer clinical trial.
- Specific responsibilities include extracting clinical data from REDCAP Electronic Health System.
- Collecting and analyzing adverse events in 213 breast cancer patients.
- Performing statistical analysis.
- Creating clinical brochures and verbiage for recruitment of subjects into clinical trials.
- Attending regular meetings to determine supplies needed for clinical enrollment.
- Providing expert insights into recruiting diverse populations into genomic medicine studies funded by the NHGRI-IGNITE network, and designing new studies from clinical trial data.
- Researched industry innovations and emerging treatments to improve care delivery.
Clinical Pharmacology Fellow
Federal Drug Agency
06.2019 - 08.2019
- Responsible for evaluating racial/ethnic differences in the safety, efficacy, and pharmacokinetics in 213 new molecular entities.
- Improving and updating FDA medical and drug databases.
- Reviewing medical literature and FDA public databases in pharmacogenetic, pharmacokinetic, safety, and efficacy.
- Collecting data on adverse drug events across racial/ethnic groups in 213 NME's.
- Qualitative data analyses.
- Reporting of racial and ethnic differences in NME's.
- Compiled data in reports and other documents using excel, R, and word.
- Collaborated with team to optimize workflow and achieve objectives.
Senior Clinical Research Scientist
University of Illinois at Chicago
01.2010 - 06.2014
- Monitoring the recruitment of patients at multiple clinical sites.
- Creating clinical brochures and standard operating procedures (SOP).
- Providing data support for IRB submission.
- Supervising clinical coordinators and the recruitment of diverse populations into clinical trials.
- Conducting telephone interviews to determine subject eligibility, obtaining informed consent and HIPAA authorization.
- Ensured high-quality data collection by developing robust protocols and providing comprehensive training for clinical staff.
- Promoted a culture of quality within the research team, implementing best practices for documentation, data management, and process improvement.
- Designed, constructed and implemented research proposals, protocols and procedures.
- Performed data analysis and interpretation of results from clinical trials.
- Trained and mentored new staff to achieve efficiency and maintain daily operational consistency.
- Assisted with day-to-day operations, working efficiently and productively with all team members.
- Worked effectively in fast-paced environments.
Education
Ph.D. - Medical & Molecular Genetics
Indiana University School of Medicine
Indianapolis, IN08.2021
Skills
- Monitoring clinical trial enrollment across multiple sites
- Clinical drug trials
- Genomic Analysis
- Database Management
- Statistical modeling
- Project Management
- Research coordination
- Critical Thinking
- Teamwork and Collaboration
- Time Management
- Investigational New Drug Application (IND), New Drug Application (NDA) in Therapeutic Products
- Supervision and leadership
Curriculum Vitae
Skilled professional with a Doctor of Philosophy (Ph.D.) in Medical and Molecular Genetics and 10+ years of experience in providing expert insights into recruiting diverse populations into genomic clinical trials. Ensuring studies are conducted, recorded, and reported in accordance with the protocol, standard operating procedures (SOPs), ICH-GCP and CLIA standards. Monitor the completion of data collection from multiple clinical sites. Performing lead data analyses from large clinical data sets, including the INGENIOUS pharmacogenetic and ECOG-ACRIN breast cancer clinical trial., Ethics in Clinical Research, Oncology Clinical Trial, Project management, Regulatory requirements: FDA and Drug Control, Drug and Cosmetic Act, Investigational New Drug Application (IND), New Drug Application (NDA) in therapeutic products, Supervision of clinical coordinators, Statistical analysis, Senior Clinical Research Scientist, University of Illinois at Chicago, 08/2017, Responsible for monitoring recruitment in diverse populations and data collection from federal funded clinical trials, Supervising clinical coordinators and the recruitment of diverse populations into clinical trials, Creating clinical brochures and standard operating procedures (SOP), Monitoring the recruitment of patients at multiple clinical sites, Monitor the completion of data collection from food frequency questionnaires, Providing data support for IRB submission, Performing data analysis using PLINK and SPSS, Verify data in source documents are in agreement with source, initiate data query resolution and confirm resolution in timely manner, Conduct telephone interviews to determine subject eligibility. Obtain informed consent and HIPAA authorization, PhD Medical & Molecular Genetics student, Indiana University, 08/2017, 08/2021, Responsible for designing and implementing research studies from the large Ingenious pharmacogenetic clinical trial and the ECOG-ACRIN breast cancer clinical trial, Extract clinical data from REDCAP and Electronic Health Systems, Collect and analyze adverse events in breast cancer patients, Perform statistical analysis, Create clinical brochures and verbiage for recruitment studies, Attend regular meetings to determine supplies needed for clinical trial, Provide expert insights into recruiting diverse populations into genomic medicine studies funded by the NHGRI-IGNITE network, Designing new studies from clinical trial data, Clinical Pharmacology Fellow, Federal Drug Agency, 06/2019, 08/2019, Responsible for evaluating racial/ethnic differences in the safety, efficacy, and pharmacokinetics in 213 new molecular entities, Improve and update FDA medical and drug databases, Present results to department heads, Reviewed medical literature and FDA public databases in pharmacogenetic, pharmacokinetic, safety, and efficacy, Collect data on adverse drug events across racial/ethnic groups in 213 NME's, Qualitative data analyses, Presentation, publication and reporting of racial and ethnic differences in NME's, Doctor of Philosophy (Ph.D.), Medical and Molecular Genetics, Cancer Biology, Indiana University School of Medicine, Indianapolis, IN, 08/2021, Master of Science, Molecular Biology, Chicago State University, Chicago, IL, Bachelor of Science, Biology, Chicago State University, Chicago, IL
Timeline
Clinicial Genomic Scientist
HELIX
06.2023 - 02.2024
Clinical Genomic Scientist
Baylor Genetics (Industry)
11.2021 - 06.2023
Clinical Pharmacology Fellow
Federal Drug Agency
06.2019 - 08.2019
PhD Medical & Molecular Genetics Student
Indiana University
08.2017 - 08.2021
Senior Clinical Research Scientist
University of Illinois at Chicago
01.2010 - 06.2014
Ph.D. - Medical & Molecular Genetics
Indiana University School of Medicine
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