Summary
Overview
Work History
Education
Skills
Publications
Timeline
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EMNMANUEL CHISOM OBIORAH

Oakland,CA

Summary

Creative and detail-oriented professional with a strong background in biotechnology and biopharmaceutical research. Proficient in protein engineering and data analysis. Leveraging my extensive experience in machine learning, molecular biology, and leadership, I am enthusiastic about contributing to Pivot Bio’s groundbreaking work in agriculture as a Research Associate I.

Overview

5
5
years of professional experience

Work History

Senior Manufacturing Associate

BioMarin Pharmaceutical
2022.05 - Current
  • Developed and refined Standard Operating Procedures (SOPs) while cross-training across multiple shifts to achieve a thorough understanding of end-to-end company bioprocesses, both in Upstream and Downstream.
  • Operated large-scale bioprocess equipment for cell culture and purification, including advanced chromatography and protein purification techniques.
  • Led shift updates, collaborated with cross-functional teams, and trained employees to ensure smooth operations and achieve collective objectives.
  • Performed compliance audits on batch records, ensured adherence to good documentation practices, and conducted quality control testing.
  • Collaborated with the EHS team to re-evaluate and enhance safety and security measures, optimizing them for increased efficiency, cost savings, and improved employee safety.
  • Acted as the Subject Matter Expert (SME) for key bioprocess operations, providing specialized knowledge and guidance.
  • Conducted cell culture work with E. coli, focusing on sampling and monitoring cell growth.

Research Assistant

Genentech
2021.03 - 2022.02
  • Worked with Mammalian cells.
  • Developed methods for ion mobility (IM) and liquid chromatography-mass spectrometry (LC-MS) systems, analyzing protein samples for molecular structure, weight, and identity.
  • Presented research findings at the 2021 ASMS Conference, contributing to advancements in protein engineering and therapeutic solutions.

Teaching Assistant (Machine Learning)

San Francisco State University
2020.01 - 2021.05
  • Assisted in teaching machine learning concepts and applications for analyzing large-scale biological data, including Alzheimer's disease research.
  • Guided students through machine learning techniques and data analysis processes.

Education

Bachelor of Science in Biochemistry/Computer Applications -

San Francisco State University
San Francisco, CA
05.2023

A.S. in Liberal Arts And Sciences -

College of Alameda
Alameda, CA
05.2018

Skills

  • Applied machine learning to analyze large datasets in Alzheimer’s therapeutic research.
  • Analyzed experimental data with Magicplots, Xcalibur, and R-studio for bioprocess and protein design.
  • Skilled in LC-MS, HPLC, NDMA analysis, and chromatography for protein purification.
  • Managed shift updates, and coordinated cross-functional collaboration.
  • Expert in GMP and regulatory compliance for biotech processes.
  • Proficient in mobility studies and mass spectrometry for molecular analysis.
  • Proficient in LIMS, Oracle, EBS, and MES.

Publications

Microflow size exclusion chromatography to preserve micromolar affinity complexes and achieve subunit separations for native state mass spectrometry, ES Hecht, EC Obiorah, X Liu, L Morrison, H Shion, M Lauber, Journal of Chromatography A, 1685, 2022, 10.1016/j.chroma.2022.463638

Timeline

Senior Manufacturing Associate

BioMarin Pharmaceutical
2022.05 - Current

Research Assistant

Genentech
2021.03 - 2022.02

Teaching Assistant (Machine Learning)

San Francisco State University
2020.01 - 2021.05

Bachelor of Science in Biochemistry/Computer Applications -

San Francisco State University

A.S. in Liberal Arts And Sciences -

College of Alameda
EMNMANUEL CHISOM OBIORAH