EMNMANUEL CHISOM OBIORAH
Oakland,CA
Summary
Creative and detail-oriented professional with a strong background in biotechnology and biopharmaceutical research. Proficient in protein engineering and data analysis. Leveraging my extensive experience in machine learning, molecular biology, and leadership, I am enthusiastic about contributing to Pivot Bio’s groundbreaking work in agriculture as a Research Associate I.
Overview
5
5
years of professional experience
Work History
Senior Manufacturing Associate
BioMarin Pharmaceutical
05.2022 - Current
- Developed and refined Standard Operating Procedures (SOPs) while cross-training across multiple shifts to achieve a thorough understanding of end-to-end company bioprocesses, both in Upstream and Downstream.
- Operated large-scale bioprocess equipment for cell culture and purification, including advanced chromatography and protein purification techniques.
- Led shift updates, collaborated with cross-functional teams, and trained employees to ensure smooth operations and achieve collective objectives.
- Performed compliance audits on batch records, ensured adherence to good documentation practices, and conducted quality control testing.
- Collaborated with the EHS team to re-evaluate and enhance safety and security measures, optimizing them for increased efficiency, cost savings, and improved employee safety.
- Acted as the Subject Matter Expert (SME) for key bioprocess operations, providing specialized knowledge and guidance.
- Conducted cell culture work with E. coli, focusing on sampling and monitoring cell growth.
Research Assistant
Genentech
03.2021 - 02.2022
- Worked with Mammalian cells.
- Developed methods for ion mobility (IM) and liquid chromatography-mass spectrometry (LC-MS) systems, analyzing protein samples for molecular structure, weight, and identity.
- Presented research findings at the 2021 ASMS Conference, contributing to advancements in protein engineering and therapeutic solutions.
Teaching Assistant (Machine Learning)
San Francisco State University
01.2020 - 05.2021
- Assisted in teaching machine learning concepts and applications for analyzing large-scale biological data, including Alzheimer's disease research.
- Guided students through machine learning techniques and data analysis processes.
Education
Bachelor of Science in Biochemistry/Computer Applications -
San Francisco State University
San Francisco, CA05.2023
A.S. in Liberal Arts And Sciences -
College of Alameda
Alameda, CA05.2018
Skills
- Applied machine learning to analyze large datasets in Alzheimer’s therapeutic research
- Analyzed experimental data with Magicplots, Xcalibur, and R-studio for bioprocess and protein design
- Skilled in LC-MS, HPLC, NDMA analysis, and chromatography for protein purification
- Managed shift updates, and coordinated cross-functional collaboration
- Expert in GMP and regulatory compliance for biotech processes
- Proficient in mobility studies and mass spectrometry for molecular analysis
- Proficient in LIMS, Oracle, EBS, and MES
Publications
Microflow size exclusion chromatography to preserve micromolar affinity complexes and achieve subunit separations for native state mass spectrometry, ES Hecht, EC Obiorah, X Liu, L Morrison, H Shion, M Lauber, Journal of Chromatography A, 1685, 2022, 10.1016/j.chroma.2022.463638
Timeline
Senior Manufacturing Associate
BioMarin Pharmaceutical
05.2022 - Current
Research Assistant
Genentech
03.2021 - 02.2022
Teaching Assistant (Machine Learning)
San Francisco State University
01.2020 - 05.2021
Bachelor of Science in Biochemistry/Computer Applications -
San Francisco State University
A.S. in Liberal Arts And Sciences -
College of Alameda
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