Fatemeh Nouri Emamzadeh
Land O' Lakes,FL
Summary
Passionate and highly motivated professional with more than 15 years’ post-graduate experience in immunology, oncology, gene therapy and neuroscience. Extensively skilled in experimental design and development, guiding and mentoring, trouble shooting, data analyzing and managing multiple priorities. Willingness to take on added responsibilities to meet team goals with a high degree of accuracy. Dedicated to help team to achieve company goals, improving efficiency and effectiveness, identifying and reducing expenses to make high quality products be accessible and affordable for everybody.
Overview
19
19
years of professional experience
Work History
Analytical Development scientist II
Iovance Biotherapeutics
08.2022 - Current
- Serve as an analytical technical scientist for TALEN-edited tumor-infiltrating T-lymphocytes (TILs) in-process and release methods.
- Develop characterization strategies to characterize engineered T-cells using multi-parameter flow cytometry, dd-PCR, NGS, Sanger sequencing, ELISA.
- Conducted experiments in GMP laboratory environment for product development, qualification and validation.
- Serve as a key expert to evaluate new technologies and laboratory techniques to improve quality and robustness of faster and more cost effective analysis.
- Evaluating platforms of cellular therapies including tumor infiltrating lymphocytes (TIL), natural killer (NK) cells, CAR-T cells.
- Monitoring and recording changes during experiments and perform complex troubleshooting by assay or instrument modifications.
FDA staff fellow
FDA
08.2020 - 08.2022
- Supervised other staff scientists and guided them to promote productivity.
- Trained new employees and ensured the lab workforce understands all cGMP regulations, and FDA internal policies.
- Monitored team performance and provided constructive feedback to increase productivity and maintain quality standards.
- Performed research to serve as basis for new findings, grant writing and publication.
Postdoctoral Fellow
FDA
09.2016 - 08.2020
- I was trained and certified in FDA’s GLP/GMP/GCP guidelines and also ICH, ISO guidelines.
- Performed gene expression profiling, epigenetic changes monitoring, mi-RNA and RNAi screening and morphological profiling of biopsy samples of triple negative breast cancer (TNBC), Pancreatic cancer, Lung cancer and Lupus.
- Evaluated potency, efficacy and toxicity of drugs for phenotype restoring and inhibition of cell cycle.
- Maintained records of research findings with analysis and evaluation of results.
- Prepared tables, graphs and fact sheets to summarize research results.
- Assisted with preparing project-related reports, presentations and manuscripts.
Lab manager
Medigate
10.2015 - 08.2016
- Managed and motivated employees to be productive and engaged in work.
- Kept laboratory in compliance with applicable guidelines and laws.
- Kept equipment maintained, facility organized and inventory stocked.
- Identified and troubleshot technical issues related to laboratory procedures.
- Prepared reports to document laboratory results and findings.
Assistant Professor
Azad University
10.2014 - 03.2016
- Supervised graduate student and helped them with writing effective project proposals, guided them to experimental design, running experiments, trouble shooting and data analysis.
- Organized class discussions and provided academic advisement.
- Collaborated with faculty members on multidisciplinary projects.
- Evaluated students learning and performance and provided constructive feedback.
Medical device sale representative
10.2004 - 10.2009
- Met with physicians, directors and healthcare executives to successfully sell mammography and ultrasound devices.
- Followed up with clinical contacts weekly to check on needs and offer new solutions.
Education
Graduate Certificate in Regulatory Sciences - Regulatory Sciences
University of Arkansas For Medical Sciences (UAMS)
4301 W Markham St, Little Rock, AR 7220507.2022
Ph.D. - Biomedicine
Lancaster University
Bailrigg, Lancaster LA1 4YW, United Kingdom07.2014
Master of Science - Genetics
University of Isfahan
Darvazeh Shiraz, Isfahan, Isfahan, Iran. 06.2009
Bachelor of Science - Biology
University of Isfahan
Darvazeh Shiraz, Isfahan, Isfahan, Iran. 07.2006
Skills
- CGMP Regulations
- Assay Development
- SOP Adherence
- Immunotherapy: tumor-infiltrating lymphocyte (TIL) therapy, T cell receptor–engineered T (TCR-T) cell therapy, and chimeric antigen receptor T (CAR-T) cell therapy
- Neuroscience
- Multicolor flow cytometry, quantitative PCR (qPCR) and digital PCR (dPCR), Fluorescence Microscopy, ELISA, DNA Sequencing, etc
- Timelines and Milestones
- Toxicology
- Experiment Protocol Development
- IND/BLA/NDA
Publications
• 2023-04
Surguchov, A.; Emamzadeh, F.N.; Titova, M.; Surguchev, A.A. Controversial Properties of Amyloidogenic Proteins and Peptides: New Data in the COVID Era. Biomedicines 2023, 11, 1215. https://doi.org/10.3390/biomedicines11041215
• 2020-07
Emamzadeh F. N, Word B, Cotton E, et al. Modulation of Estrogen α and Progesterone Receptors in Triple Negative Breast Cancer Cell Lines: The Effects of Vorinostat and Indole-3-Carbinol In Vitro. Anticancer Res. 2020;40(7):3669-3683. doi:10.21873/anticanres.14356
• 2019-06
Surguchov A, Emamzadeh F. N, Surguchev AA. Amyloidosis and Longevity: A Lesson from Plants. Biology 8: 43.
• 2019-01
Surguchev AA, Emamzadeh F. N, Surguchov A. Cell Responses to Extracellular α- Synuclein. Molecules. 24: 305.
• 2018-08
Emamzadeh, F. N, & Surguchov, A. Parkinson’s Disease: Biomarkers, Treatment, and Risk Factors. Frontiers in Neuroscience. 12: 612.
• 2017-07
Emamzadeh, F.N. Role of Apolipoproteins and α-Syn in Parkinson’s Disease. J Mol Neuro. 62: 344.
• 2017-09
Emamzadeh, F.N & Allsop, D.α-Synuclein interacts with lipoproteins in plasma. J Mol Neurosci. 63: 165.
· 2017-10
Emamzadeh F.N. A Multipurpose Preclinical and Clinical Diagnostic Tool. Journal of Biomedical Science & Applications. Vol. 1 No. 1:4.
• 2016-05
Emamzadeh F.N. Alpha-synuclein structure, functions, and interactions. J Res Med Sci. 21: 29.
• 2016-08
Emamzadeh, F.N, Aojula H, McHugh PC, Allsop D. Effects of different isoforms of apoE on aggregation of the α ‐synuclein protein implicated in Parkinson’s disease. Neuroscience Lett. 618: 146-151.
• 2016-06
Hojati Z, Emamzadeh F.N, Dehghanian F. Association between polymorphisms of exon 12 and exon 24 of JHDM2A gene and male.
References
Dr. Beverly Lyn-Cook, FDA
Senior Interdisciplinary Research Biologist
E-mail: Beverly.lyn-cook@fda.hhs.gov
Phone Number: 870 543 7965
Dr. George Hammons, FDA
E-mail: George.Hammons@fda.hhs.gov
Phone Number: 870 543 7121
Ms. Beverly Word, FDA
E-mail: Beverly.word@fda.hhs.gov
Phone Number: 870 543 7968
Dr. Takashi Kasi,
MD at Kyoto Prefectural University, Japan
E-mail: kasaita@koto.kpu-m.ac.jp
Phone Number: +81 75 366 8328
Timeline
Analytical Development scientist II
Iovance Biotherapeutics
08.2022 - Current
FDA staff fellow
FDA
08.2020 - 08.2022
Postdoctoral Fellow
FDA
09.2016 - 08.2020
Lab manager
Medigate
10.2015 - 08.2016
Assistant Professor
Azad University
10.2014 - 03.2016
Medical device sale representative
10.2004 - 10.2009
Graduate Certificate in Regulatory Sciences - Regulatory Sciences
University of Arkansas For Medical Sciences (UAMS)
Ph.D. - Biomedicine
Lancaster University
Master of Science - Genetics
University of Isfahan
Bachelor of Science - Biology
University of Isfahan
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