Summary
Overview
Work History
Education
Skills
Certification
Timeline
Generic

Fazle Rabbi

Foxborough,MA

Summary

Highly-motivated employee with desire to take on new challenges. Strong work ethic, adaptability, and exceptional interpersonal skills. Adept at working effectively unsupervised and quickly mastering new skills.

Overview

9
9
years of professional experience
1
1
Certification

Work History

Senior Associate, Quality Control

Moderna
Norwood, MA
03.2023 - Current
  • Conducted analytical testing of drug products containing lipid nanoparticles (LNP) to assess efficacy and quality.
  • Performed HPLC and RP-HPLC for quantitative analysis of active pharmaceutical ingredients (API) in lipid-based formulations.
  • Utilized compendial methods such as pH measurement and osmometry to ensure formulation consistency and compliance.
  • Implemented dynamic light scattering (DLS) for particle size distribution analysis and evaluating percent encapsulation using methylene blue assays.
  • Gathered and recorded the concentration of mRNA content material encapsulated within LNPs through light absorption from UV-Vis lab instrumentation and software.
  • Conducted particulate matter analysis along with supplemental destructive methods through membrane-based filtration, followed by microscopic inspection of LNPs to determine the presence of aggregated particles and contamination sources.
  • Collaborated with cross-functional teams to optimize formulation parameters and improve product stability.
  • Implemented laboratory automation solutions to improve throughput and reduce variability in high-demand workflows.
  • Supported cGMP-compliant documentation, including investigations, deviations, and CAPAs, maintaining regulatory compliance and operational integrity.
  • Trained cross-functional team members in QC methodologies, reagent preparation, and data analysis, strengthening team capabilities and productivity.
  • Provided precise, regulatory-compliant test results through LabVantage, facilitating informed decision-making in critical manufacturing processes.

Associate Scientist

Amgen
Thousand Oaks, CA
07.2021 - 02.2023
  • Led and supported stability studies using advanced analytical techniques, including SEC, CEX, and CE, addressing critical challenges in protein drug products to ensure quality.
  • Utilized 32Karat/PA 800 Plus instrumentation for CE-SDS to generate data for assessing purity, stability, and characterization of monoclonal antibodies in project-based research.
  • Performed concentration analysis of samples via Solo-VPE to determine the bioavailability and efficacy of the product.
  • Developed and transferred phase-appropriate methods for stability testing, ensuring compliance with international regulatory standards.
  • Designed and executed pre-formulation experiments for monoclonal antibody drug product stability evaluation.
  • Utilized HPLC, SEC, particulate counting (MFI, HIAC), and capillary electrophoresis (CE-SDS) to assess degradation pathways.
  • Provided data-driven recommendations for formulation optimization and improved drug product stability.
  • Optimized workflows for high-throughput microbial analysis, streamlining data processing for drug discovery.
  • Collaborated globally to ensure compliance with international quality standards during regulatory submissions.

Scientific Associate

PerkinElmer Genomics
Santa Clarita, CA
10.2020 - 08.2021
  • Oversaw high-volume RNA/DNA extraction and PCR operations for COVID-19 testing, efficiently processing 40,000 samples daily to support public health efforts.
  • Refined liquid automation technologies by troubleshooting and resolving technical issues, ensuring seamless operation and compliance with CDPH regulations.
  • Designed and optimized microbial contamination analysis protocols, ensuring compliance with regulatory standards.
  • Mentored and coached new hires in high-throughput testing workflows, fostering operational excellence.

Genetics Data Analyst

Fugetron Corporation
North Hollywood, CA
08.2019 - 07.2021
  • Analyzed and interpreted a proprietary SNP database, delivering a comprehensive 600-page pharmacogenomics report that informed strategic initiatives.
  • Collaborated with industry experts to develop and enhance drug-to-gene interaction algorithms, significantly increasing data processing efficiency and accuracy.
  • Presented actionable insights to stakeholders, enabling data-driven decisions on algorithm applications and driving project success.

Undergraduate Lab Assistant

UCSD Department of Biological Sciences
San Diego, CA
01.2016 - 06.2019
  • Conducted microbial growth monitoring and contamination analysis in controlled laboratory environments.
  • Engineered recombinant plasmids and performed site-directed mutagenesis for molecular studies.
  • Designed guide RNA for CRISPR-Cas9 project targeting E. coli genes; validated edits via PCR and gel electrophoresis.
  • Investigated cellular signaling using immunodetection, western blotting, and ELISA methods.
  • Implemented RNA interference through detection and isolation of the unc-22 gene in C. elegans to perform phenotypic analysis of the twitching movement and evaluate gene function.
  • Executed protocols related to media, buffer preparation, cell culture/differentiation, and cell harvesting/formulation.
  • Routinely performed cell culture related to hybridoma development, screening, and monoclonal antibody selection.
  • Performed mass spectrometry to identify unknown compounds and evaluate sample purity, supporting compound characterization and data analysis for analytical research.

Education

Master of Science - Bioengineering

University of California, Riverside
Riverside, CA
12-2023

Bachelor of Science - Biochemistry And Cell Biology

University of California, San Diego
La Jolla, CA
06-2019

Skills

  • Analytical testing: pH analysis, osmolality, PCR, RT-qPCR, nucleic acid extraction, DNA construct design, CE-SDS, ELISA, High Throughput Screening, methylene blue encapsulation, NaOH digestion
  • Assay/Pivotal support: protein characterization, protein purification, lipid nanoparticles formulation, mRNA drug product characterization, process development, UV-Vis Spectrophotometry
  • HPLC analysis: HPLC/UPLC, SEC, CEX, RP-HPLC
  • Particle size analysis: dynamic light scattering, MFI, HIAC
  • Regulatory compliance: GMP and non-GMP regulations, GLP
  • Data analysis: LabVantage, Chromeleon, BioVIA, LIMS
  • Laboratory automation- Janus G3 Liquid Handler (similar to Hamilton), Chemagen 360, Andrews

Certification

  • UCSD Data Science and Visualization Bootcamp Extension
  • ARTEL Pipette

Timeline

Senior Associate, Quality Control

Moderna
03.2023 - Current

Associate Scientist

Amgen
07.2021 - 02.2023

Scientific Associate

PerkinElmer Genomics
10.2020 - 08.2021

Genetics Data Analyst

Fugetron Corporation
08.2019 - 07.2021

Undergraduate Lab Assistant

UCSD Department of Biological Sciences
01.2016 - 06.2019

Master of Science - Bioengineering

University of California, Riverside

Bachelor of Science - Biochemistry And Cell Biology

University of California, San Diego

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