GEORGE AUGUSTINE
Corvallis,OR
Summary
Innovative life scientist with 4+ years of postdoctoral research experience in genetic code expansion, bioorthogonal chemistry, protein engineering, and regenerative medicine. Strong publication record with interdisciplinary expertise in molecular biology, stem cell engineering, therapeutic biomaterials, and viral gene delivery systems.
Overview
4
4
years of professional experience
Work History
Postdoctoral Research Scholar
Oregon State University
01.2022 - Current
Implemented site-specific tagging of DNA-binding proteins using Tetrazine-sTCO-fluorophore bioorthogonal ligations.
Developed a baculovirus-mediated delivery system for orthogonal protein labeling in human cells, representing a significant advancement with far-reaching implications.
Introduced in-cell 19F NMR platforms, which are cutting-edge tools allowing for real-time monitoring of protein-ligand interactions in live human cells, holding exciting potential for various applications.
Collaborated on industry-assisted projects, including the development of protein-antibody conjugates and the expression of therapeutic enzymes using photocaged amino acids in mammalian cells.
Postdoctoral Research Fellow
Soonchunhyang Institute of Medibio Science (SIMS)
05.2021 - 12.2021
- Research in tendon tissue engineering and regenerative medicine using stem cell-based approaches by employing PDRN.
Education
Ph.D. - Biochemistry and Biotechnology
Anna University
01.2020
M.Sc. - Microbial Gene Technology
Madurai Kamaraj University
01.2012
B.Sc. - Plant Biology and Plant Biotechnology
University of Madras
01.2010
Skills
- Site-Directed Mutagenesis & Molecular Cloning
- Protein Engineering & Site-Specific Labeling
- Baculovirus/Lentivirus-mediated Gene Delivery
- DNA Transfection, immunoprecipitation techniques, qPCR, stem Cell Isolation, Differentiation, and Engineering
- Recombinant Protein Expression & Purification from E coli, Yeast and Mammalian Cells (FPLC, AKTA)
- Advanced Fluorescence Microscopy & Cell Imaging
- Cancer Biology and Immunology Assays (ELISA, FACS, Immunohistochemistry, Tube Formation assy
- Bioinformatics, Genome Analysis, HPLC, MALDI-TOF, SAXS, CD Spectroscopy
Timeline
Postdoctoral Research Scholar
Oregon State University
01.2022 - Current
Postdoctoral Research Fellow
Soonchunhyang Institute of Medibio Science (SIMS)
05.2021 - 12.2021
M.Sc. - Microbial Gene Technology
Madurai Kamaraj University
B.Sc. - Plant Biology and Plant Biotechnology
University of Madras
Ph.D. - Biochemistry and Biotechnology
Anna University
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