Ginevra Bugani

PhD candidate in Advances in Infectious Diseases, Microbiology, Legal Medicine, and Public Health Sciences with extensive experience in immunology, infectious disease research, and translational science. Skilled in experimental design, data analysis, and advanced laboratory techniques. Highly curious, adaptable, and motivated to apply scientific expertise and problem-solving abilities in a dynamic pharmaceutical or biotechnology environment.

• Gut TLRs and IFN pathways mRNA expression and frequencies of CD4+ T cell expressing CD38 or HLA-DR go in parallel during HIV immunopathogenesis. Luca Maddaloni; Ginevra Bugani; Letizia Santinelli; Alessandro Lazzaro; Federica Frasca; Matteo Fracella; Giancarlo Ceccarelli; Claudio M. Mastroianni; Carolina Scagnolari; Gabriella d'Ettorre. Immunol Lett.
• Machine Learning Reassessment of Serum Immune Factors Shows No Unique Immune Profiles Linked to Disease Outcomes in SARS-CoV-2-infected Patients at Hospital Admittance. Rossi S, Capone I, Cabri E, Giabelli A, Rossoni I, Romagnoli G, Santini SM, Marcantonio C, Giuseppetti R, Villano U, Bruni R, Ciccaglione AR, Frasca F, d'Auria A, Bugani G, d'Ettorre G, Antonelli G, Scagnolari C, Fratelli M, Gabriele L. Eur J Immunol. 2025
• Long COVID and Innate Immune Signatures in Working-Age Adults: A Cross-Sectional Study. Letizia Santinelli, Elio Gentilini Cacciola, Luca Bortolani, Marco Ridolfi, Luca Maddaloni, Federica Frasca, Matteo Fracella, Ginevra Bugani, Gabriella D’Ettorre, Claudio M Mastroianni, Gabriele D’Ettorre, Giancarlo Ceccarelli.
• Pattern recognition receptors expression and activation in COVID-19 and long COVID: from SARS-CoV-2 escape mechanisms to emerging immunotherapies. Luca Maddaloni, Ginevra Bugani, Matteo Fracella, Camilla Bitossi, Alessandra D'Auria, Francesca Aloisi, Abir Azri, Letizia Santinelli, Manel Ben M'Hadheb, Alessandra Pierangeli, Federica Frasca, Carolina Scagnolari.
• Interferons in human papillomavirus infection: antiviral effectors or immunopathogenic role?Matteo Fracella and Ginevra Bugani, Luca Maddaloni, Federica Frasca, Alessandra D’Auria, Letizia Santinelli, Alessandra Pierangeli, Gabriella d’Ettorre and Carolina Scagnolari.
• High rates of anal Merkel Cell Polyomavirus and HPV co-infection among people living with HIV. J Med Virol. Passerini S, Fracella M, Benvenuto D, Bugani G, D'Auria A, Coratti E, Babini G, Moens U, Cavallari EN, Torti C, Antonelli G, Ciccozzi M, Pierangeli A, d'Ettorre G, Scagnolari C, Pietropaolo V.
• An Update on the Entomology, Virology, Pathogenesis, and Epidemiology Status of West Nile and Dengue Viruses in Europe (2018–2023). Federica Frasca and Leonardo Sorrentino, Matteo Fracella, Alessandra D’Auria, Eleonora Coratti, Luca Maddaloni , Ginevra Bugani, Massimo Gentile, Alessandra Pierangeli, Gabriella d’Ettorre and Carolina Scagnolari. Tropical Medicine and Infectious Disease.
• Could SP-A and SP-D Serum Levels Predict COVID-19 Severity? International Journal of Molecular Sciences. Maddaloni L, Zullino V, Bugani G, Lazzaro A, Brisciani M, Mastroianni CM, Santinelli L, Ruberto F.
• Differential expression of type I interferon and inflammatory genes in SARS-CoV-2-infected patients treated with monoclonal antibodies. L.Maddaloni, L. Santinelli, G. Bugani, E.G. Cacciola, A.Lazzaro, C.M. Lofaro, S. Caiazzo, F. Frasca, M. Fracella, C. Ajassa, C. Leanza, A. Napoli, L. Cinti, A. Gaeta, G. Antonelli, G. Ceccarelli, C M. Mastroianni, C.Scagnolari, G. d'Ettorre. Immunity, Inflammation and Disease, 2023.
• Cellular Immune Profiling of Lung and Blood Compartments in Patients with SARS-CoV-2 Infection. Santinelli, L.; Lazzaro, A.; Sciarra, F.; Maddaloni, L.; Frasca, F.; Fracella, M.; Moretti, S.; Borsetti, A.; Bugani, G.; Alessandri, F.; Zullino, V.; Ruberto, F.; Pugliese, F.; Sorrentino, L.; Gianfrilli, D.; Isidori, A.; Venneri, M.A.; Mastroianni, C.M.; Ceccarelli, G.; d’Ettorre, G. Pathogens 2023.
• Alterations in the expression of IFN lambda, IFN gamma, and Toll like receptors in severe COVID-19 patients. Leonardo Sorrentino, Matteo Fracella, Federica Frasca, Alessandra D'Auria, Letizia Santinelli, Luca Maddaloni, Ginevra Bugani, Camilla Bitossi, Massimo Gentile, Giancarlo Ceccarelli, Ombretta Turriziani, Claudio Maria Mastroianni, Guido Antonelli, Gabriella D'Ettorre, Alessandra Pierangeli, Carolina Scagnolari. Microorganisms.
• Immune Reconstitution and Safe Metabolic Profile after the Switch to Bictegravir/Emtricitabine/ Tenofovir Alafenamide Fumarate among Virologically Controlled PLWH: A 96 Week Update from the BICTEL Cohort. Alessandro Lazzaro, Diana Bianchini, Elio Gentilini Cacciola, Ivano Mezzaroma, Mario Falciano, Carolina Andreoni, Caterina Fimiani, Letizia Santinelli, Luca Maddaloni, Ginevra Bugani, Giancarlo Ceccarelli, Claudio Maria Mastroianni and Gabriella d’Ettorre. Viruses.
• Luca Maddaloni, Valentina Tirelli, Ginevra Bugani, et al. Previous COVID-19 vaccination modulates type I interferon and natural killer cell responses during SARS-CoV-2 infection. Authorea. 2025.