Summary
Overview
Work History
Education
Skills
Awards and Scholarships
Publications
Invited Oral Talks at Conferences
Links
References
Timeline
Generic

Hadia M. Abdelaal

Immunologist & Imaging Specialist
Ijamsville,MD

Summary

A highly skilled, innovative, and detail-oriented biomedical immunologist with extensive expertise in CD8 T cell immunology, immunotherapy, viral pathogenesis, and host-pathogen interaction. Recipient of several highly selective scholarships, fellowships, and travel awards. Demonstrated ability to communicate scientific information by presentations at scientific conferences and multiple peer-reviewed publications. Three years of immunology teaching experience at University of Minnesota. Committed to utilizing immunology expertise to help cure cancer and infectious diseases.

Overview

3
3
years of professional experience

Work History

Scientist I

Frederick National Laboratory For Cancer Research
Frederick, MD
05.2022 - Current

Senior Research Scientist

RTI, LLC
Brookings, SD
12.2020 - 08.2021

Post-Doctoral Research Associate

University Of Minnesota
Minneapolis, MN
01.2019 - 12.2020

Education

Ph.D. - Immunology

University of Minnesota - Twin Cities
Minneapolis, MN

Master of Science - Microbiology

Zagazig University
Egypt

Bachelor of Pharmaceutical Science -

Zagazig University
Egypt

Skills

  • Fresh, Frozen, Paraffin-embedded tissue sectioning
  • RNAscope In Situ Hybridization
  • Immunofluorescence
  • In situ MHC Class I tetramer staining to detect virus or tumor specific CD8 T cells
  • Confocal Microscopy (Leica, Zeiss, Olympus Fluoview)
  • Aperio tissue scanner
  • Quantitative image analysis
  • Adobe Photoshop
  • Cell culture
  • Gamma retroviral vector production for gene therapy
  • Production of CAR-T cells (Transduction of PBMCs)
  • Evaluation of CAR-T cells Phenotype
  • Multicolor Flow cytometry
  • Virus Isolation, Propagation and Titration
  • ELISA
  • Serum Neutralization Assay
  • Experiment Design
  • Good Laboratory Practices (GLP)
  • Deep-dive data analysis
  • Statistical analysis/ GraphPad Prism
  • Documentation expertise
  • Basic microbiological skills
  • Teamwork/Training Employee

Awards and Scholarships

  • American Society of Gene & Cell Therapy (ASGCT) underrepresented Minority Travel Award ($500) 2020
  • BELIEVE (Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral Eradication) travel scholarship to attend the 2019 HIV Persistence During Therapy Meeting in Miami, Florida ($2000) 2019
  • Honorable mention poster award, Research pride day, college of veterinary medicine, University of Minnesota 2019
  • Travel award and registration scholarship from the Cell and Gene Therapy for HIVCure conference ($500) 2019
  • Nominee for the 2017-2018 Doctoral Dissertation Fellowship (DDF) candidate by the Veterinary Medicine Graduate Program. DDF is the highest recognition that the University of Minnesota bestows on Ph.D. student gives the University's most accomplished PhD candidates an opportunity to devote full-time effort to an outstanding research project by providing time to finalize and write a dissertation during the fellowship year. 2017
  • Veterinary Medicine graduate program (VMED, UMN, USA) travel award ($500) 2017
  • A full Scholarship to attend the 9th IAS Conference on HIV Science, France (IAS 2017) “ I was one of the top 4.2% of more than 2500 applicants from 145 countries that were selected to receive a scholarship from the IAS 2017 Conference on HIV Science Paris, France” ($4000). 2017
  • American Society of Virology “ASV” graduate student travel award ($500) 2017
  • American Association of Immunologist “AAI” Trainee Abstract Award ($500) 2017
  • Complimentary registration to International Conference on One Medicine One Science (iCOMOs), Commons Hotel, Minnesota, Minnesota, USA ($175) 2016
  • Travel award and registration scholarship from the Cell and Gene Therapy for HIV Cure conference ($450) 2016.
  • American Association of University Women (AAUW) International Doctoral Degree Fellowship ($20,000) 2016-2017
  • Honorable mention poster award, Research pride day, college of veterinary medicine, University of Minnesota 2014
  • Egyptian Cultural & Educational Bureau PhD Scholarship Award ($200,000) 2013-2016

Publications

Newman RA, Chase CCL, Matos JR, Abdelsalam K, Buterbaugh R, Van Holland S, Abdelaal H, Woolum A, Jagannadha Sastry K. Efficacy of oleandrin and PBI-05204 against bovine viruses of importance to commercial cattle health. Antivir Chem Chemother. 2022 Jan-Dec;30:20402066221103960. doi: 10.1177/20402066221103960. PMID: 35611441; PMCID: PMC9136442.


Pampusch MS*, Abdelaal HM*, Cartwright EK, Molden JS, Davey BC, Sauve JD, et al. (2022) CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection. PLoS Pathog 18(2): e1009831. https://doi.org/10.1371/journal.ppat.1009831. *First co-author, equally contributed.


Pomplun, N. L., Vosler, L., Weisgrau, K. L., Furlott, J., Weiler, A. M., Abdelaal, H. M., Evans, D. T., Watkins, D. I., Matano, T., Skinner, P. J., Friedrich, T. C., & Rakasz, E. G. (2020). Immunophenotyping of Rhesus T‐Cell Populations. Cytometry Part A, cyto.a.24197. Immunophenotyping of Rhesus CMV-Specific CD8 T-Cell Populations - PubMed (nih.gov)


Abdelaal, H. M.; Cartwright, E. K.; Skinner, P. J. Detection of AntigenSpecific T Cells Using In Situ MHC Tetramer Staining. Int. J. Mol. Sci., 2019, 20 (20)


Abdelaal HM, Kim HO, Wagstaff R, Sawahata R, Southern PJ, Skinner PJ. Comparison of Vibratome and Compresstome sectioning of fresh primate lymphoid and genital tissues for in situ MHC-tetramer and immunofluorescence staining. Biol Proced Online. 2015 Jan 7; 17(1):2.


Connick E, Folkvord JM, Lind KT, Rakasz EG, Miles B, Wilson NA, Santiago ML, Schmitt K, Stephens EB, Kim HO, Wagstaff R, Li S, Abdelaal HM, Kemp N, Watkins DI, MaWhinney S, Skinner PJ. Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL. J Immunol. 2014 Dec 1; 193 (11):5613-25.


Li S, Folkvord JM, Rakaszc EJ, Abdelaal HM, Wagstaffa RK, Kovacsa KJ, Kima HO, Sawahataa R, MaWhinneye S, Masopust D, Connick E, and Skinnera PJ. SIV- producing cells in follicles are partially suppressed by CD8+ cells in vivo. J Virol. 2016 Nov 28;90(24):11168-11180.


Geetha H. Mylvaganam, Daniel Rios, Abdelaal HM, Smita Iyer, Gregory Tharp, Maud Mavigner, Sakeenah Hicks, Ann Chahroudi, Rafi Ahmed, Steven Bosinger, IR Williams, Pamela J. Skinner, Vijayakumar Velu, and Rama Rao Amara. Dynamics of SIV Specific CXCR5+ CD8 T cells During Chronic SIV Infection. PNAS. 2017 Feb 21; 114(8): 1976-1981.

Invited Oral Talks at Conferences

Hadia M Abdelaal, Mary S Pampusch, Edward A Berger and Pamela J Skinner. In Situ Analysis of Follicular Targeting Antiviral CD4-MBL CAR/CXCR5 T Cells in SIV Infected Rhesus Macaques. American Society of Gene & Cell Therapy (ASGCT) 23rd annual meeting, Virtual format, USA, May 2020


Hadia M Abdelaal, Mary S Pampusch, Edward A Berger and Pamela J Skinner. Location, abundance and persistence of CAR/CXCR5 transduced T cells within lymphoid tissues of SIV-infected rhesus macaques. HIV persistence during therapy 2019, Miami, Florida, USA, December 2019.


Hadia M Abdelaal, Mary S Pampusch, Edward A Berger and Pamela J Skinner. Location, abundance and persistence of CAR/CXCR5 transduced T cells within lymphoid tissues of SIV-infected rhesus macaques. The Cell and Gene Therapy for HIV Cure conference 2019, Seattle, Washington, USA, August 2019.


Hadia M Abdelaal, Shengbin Li, Ryoko Sawahata, Gwantwa Mwakalundwa, Kathryn Fraser, Geetha Mylvaganam, Mauricio Martins, David Masopust, Rama Rao Amara, David Watkins, Elizabeth Connick and Pamela J Skinner. CTL-based vaccine-induced control is associated with induction of high follicular to extra-follicular ratios of virus-specific CD8+ T cells. The American Association of Immunologist, Washington convention center, Washington Dc, USA, May 2017.


Abdelaal HM, Li S, Sawahata R, Fraser KA, Geetha H. GH, Martins MA, Folkvord J, Masopust D, Amara RR, Watkins DI, Connick L and Skinner PJ. CTL-based vaccine-induced control is associated with induction of high follicular to extra-follicular ratios of virus-specific CD8 T cells. Keystone Symposium, California, USA, March 2016.

Links

LinkedIn https://www.linkedin.com/feed/

https://scholar.google.com/citations?user=pzfyqYgAAAAJ&hl=en

References

Pamela J Skinner, Ph.D., Professor, Department of Veterinary and Biomedical Sciences, University of Minnesota. Phone 612-624-2644. E-mail: Skinn002@umn.edu.


Emily Cartwright, Ph.D. Product Marketing Specialist at Novus Biologicals. Email: ekcartwright@gmail.com


Thomas Molitor, Ph.D., Department Chair, Professor, Department of Veterinary Population Medicine (VPM). Email: molit001@umn.edu


Gwantwa Mwakalundwa, Assistant Professor in Microbiology at Metropolitan State University. E-mail:Gwantwa@umn.edu


Robin Buterbaugh, Senior Research Scientist, RTI, LLC. Emails: RButerbaugh@4rtilab.com, RButerbaugh@4rtilab.com.


Alesha Siegel, Quality and Safety Assurance manager, and Marketing Communications Specialist at RTI, LLC. Emails: Alesha.siegel@gmail.com

Timeline

Scientist I

Frederick National Laboratory For Cancer Research
05.2022 - Current

Senior Research Scientist

RTI, LLC
12.2020 - 08.2021

Post-Doctoral Research Associate

University Of Minnesota
01.2019 - 12.2020

Ph.D. - Immunology

University of Minnesota - Twin Cities

Master of Science - Microbiology

Zagazig University

Bachelor of Pharmaceutical Science -

Zagazig University
Hadia M. AbdelaalImmunologist & Imaging Specialist