Hiral Mandalia
Philadelphia,PA
Summary
Dedicated cytogenetics and molecular biologist with a strong background in genetic analysis and laboratory techniques. Seeking a challenging position in a dynamic and innovative laboratory setting where I can apply my expertise in cytogenetics, molecular biology, genomics, and bioinformatics to contribute to the development of novel therapies and diagnostics.
Overview
6
6
years of professional experience
Work History
Molecular Technologist
EmeritusDX & Freedom Pathology
04.2024 - 06.2024
- Receive, label, and analyze various samples (e.g., tissue, urine) following standard laboratory procedures.
- Perform molecular testing, including DNA extraction, microarray analysis, and real-time PCR, ensuring accurate specimen processing and timely release of patient results.
- Conduct microbiology testing following standard procedures, including sample accessioning, specimen processing, and releasing of patient results.
- Applied PCR techniques for detection of UTIs and STIs
- Strictly adhere to safety guidelines and best practices in Quality, Health, and Safety Systems.
- Proven experience working effectively in collaborative team settings.
- Assisted in maintenance of laboratory equipment and managed inventory of laboratory supplies.
Lab Technician (Molecular Biologist)
Neuberg Center For Genomic Medicine
03.2022 - 08.2023
- Demonstrated expertise in Next Generation Sequencing (NGS) technologies and molecular biology skills acquired through experience in CAP accredited laboratories
- Executed DNA & RNA extraction from fresh tissue and FFPE blocks to support NGS investigations for molecular signature that predicts response to targeted therapies
- Prepared NGS libraries using standardized protocols, including fragmentation, end-repair, adapter ligation, and PCR amplification steps
- Experienced in using LIMS for maintaining sample chains
- Performed Capillary Electrophoresis and analyzed sequencing data for SNP genotypic using Sequencer technology.
- Successfully passed multiple regulatory inspections by consistently following safety protocols and guidelines, while ensuring compliance with QC data and monitoring trends.
Junior Research Fellow (Cytogenetics)
Gujarat Cancer and Research Institute
01.2019 - 10.2020
- Received comprehensive training and demonstrated expertise in various aspects of oncology cytogenetics
- Conducted In Vitro culture of bone marrow and peripheral blood samples from both cancer patients and normal individuals
- Acquired experience in culture and harvesting methods, while performing G banded chromosome analysis to identify constitutional and acquired abnormalities using microscopy.
- Developed expertise in conducting Karyotyping analysis utilizing the Automatic karyotyping system Zeiss Axio plan2 imaging alongside IKAROS & ISIS software.
- Independently performed FISH assays for malignant tissue using Olympus BX61 fluorescence microscope and conducted solid tumor FISH analysis for cancer patients.
- Delivered scientific presentations, prepared publications, and actively participated in NABL audits, contributed for accreditation process.
- Provided guidance and conducted practical exams for cancer biology master's students during their dissertation
COVID 19 Lab under Gujarat Cancer and Research Institute
04.2020 - 05.2020
- Testing COVID19 from respiratory samples by qRT PCR technique
- Processing viral samples, RNA extraction, amplification and documentation work.
Lab Technician (Molecular Biologist)
Supratech Micropath Laboratory
07.2018 - 12.2018
- Performed DNA and RNA isolation from various biological samples using both manual and automated techniques
- Conducted various molecular biology techniques including PCR, RTPCR, ddPCR and Gel Electrophoresis
- Competent in performing automated and manual clinical assay.
- Maintained documentation on tests performed in lab.
Education
Master of Science - Cancer Biology
Gujarat Cancer & Research Institute, Gujarat University
Ahmedabad |01.2018
Bachelor of Science - Biochemistry
M.G. Science College
Ahmedabad |01.2016
Skills
- Cytogenetic Proficiency
- Next Generation Sequencing (NGS) Expertise (Molecular Biology)
- Regulatory Compliance and Quality Control
- Laboratory Techniques and Equipment Proficiency
Publications
Clinical Significance of Her 2 Gene Expression in Gastric Cancer Patients - A Retrospective Study (International Journal of Scientific Research and Reviews) ISSN: 2779-0543
Timeline
Molecular Technologist
EmeritusDX & Freedom Pathology
04.2024 - 06.2024
Lab Technician (Molecular Biologist)
Neuberg Center For Genomic Medicine
03.2022 - 08.2023
COVID 19 Lab under Gujarat Cancer and Research Institute
04.2020 - 05.2020
Junior Research Fellow (Cytogenetics)
Gujarat Cancer and Research Institute
01.2019 - 10.2020
Lab Technician (Molecular Biologist)
Supratech Micropath Laboratory
07.2018 - 12.2018
Master of Science - Cancer Biology
Gujarat Cancer & Research Institute, Gujarat University
Bachelor of Science - Biochemistry
M.G. Science College
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