Kathy Hötzel
San Bruno,CA
Summary
Laboratory based Scientist with 25 years of experience in molecular biology techniques. Proven history of applying innovative methods to developing experimental protocols. Looking for a position in a laboratory where my skills are applicable.
Overview
24
24
years of professional experience
Work History
Scientist 3
Department of Pathology, Genentech, Inc.
South San Francisco, CA
05.2013 - 10.2023
- Lead for the IHC Serum and Supernatant Screen for discovery of IHC antibodies for research projects. Coordinated cross company efforts, ran automated IHC and ISH assays, analyzed the staining results with the Pathologist, PI and team to select the best antibody candidates to move forward. Presented results and suggestions at team meetings with stakeholders.
Scientific Researcher
Department of Pathology, Genentech, Inc.
South San Francisco, CA
06.2005 - 05.2013
- Conducted research on the inhibition of hepatocellular carcinoma with antibodies targeting Notch2. Responsible for generating data essential for anti-Notch2 and anti-Jag1 antibody candidates moved into late stage research. Developed and characterized in vivo efficacy studies of anti-Notch2 ad anti-Jag1 in models of hepatocellular carcinoma. Conducted research on the inhibition of hepatocellular carcinoma with antibodies targeting FGF19. Performed critical studies of anti-FGF19 antibody candidate moved into early development. Designed, performed and analyzed in vitro assays for efficacy of anti-FGF19 antibodies in modulating cell signaling.
Life Science Research Associate I
Department of Gynecology and Obstetrics, Stanford
Stanford, CA
03.2005 - 06.2005
- Investigated the role of IGFBP-1 in hypoxic mice during embryonic development. Executed studies to analyze gene expression and protein expression in tissues from hypoxic mice by quantitative PCR and Western blot.
Associate in Research
Washington State University
Pullman, WA
05.1999 - 01.2005
- Assisted in clinical virology and development of immunization strategies for animal lentiviruses. Performed immunoprecipitaions and Western blot assays to evaluate immune response to experimental vaccines. Conducted cell based assays for in vitro detection of virus expression and titration.
Education
Bachelor of Science - Animal Science
Washington State University
Pullman, WA06-1999
Skills
- Quantitative Skills
- Results Analysis
- Lab Experiments and Research
- Project Management
- Experiment Protocol Development
- In-vitro and in-vivo assays
- Immunological assays
Timeline
Scientist 3
Department of Pathology, Genentech, Inc.
05.2013 - 10.2023
Scientific Researcher
Department of Pathology, Genentech, Inc.
06.2005 - 05.2013
Life Science Research Associate I
Department of Gynecology and Obstetrics, Stanford
03.2005 - 06.2005
Associate in Research
Washington State University
05.1999 - 01.2005
Bachelor of Science - Animal Science
Washington State University
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