Ian Wallace
BRIGHTON,MA
Summary
Preclinical In Vivo Pharmacologist with 5+ years of experience supporting oncology drug development in fast-paced biotech environments. Demonstrated leadership in target validation, PK/PD modeling, and IND-enabling pharmacology studies across CDX and PDX models. Proven ability to lead cross-functional in vivo strategy, manage external collaborations, and deliver actionable data in support of compound advancement and development candidate nomination.
Overview
9
9
years of professional experience
Work History
Senior Associate Scientist
Parabilis Medicines (Formerly Fog Pharma)
Cambridge, MA
03.2026 - Current
- Developed and optimized experimental protocols for drug formulation and delivery systems.
- Led cross-functional teams to streamline research processes, enhancing collaboration and efficiency.
- Mentored junior scientists, fostering skill development and knowledge transfer within teams.
- Analyzed complex data sets using advanced statistical tools to support decision-making in projects.
- Contributed to patent applications detailing novel discoveries made during research projects.
Associate Scientist II
Parabilis Medicines (Formerly FogPharma)
Cambridge, MA
03.2024 - Current
- Appointed in vivo pharmacology lead for the ERG program, responsible for target validation, lead optimization, and in vivo proof-of-concept studies in prostate cancer models.
- Led over 30+ PK/PD and efficacy studies to support compound prioritization during lead optimization, acting as the primary pharmacology contact across cross-functional teams.
- Generated pharmacological proof-of-concept for multiple compounds, contributing to DC nomination and progression to IND-enabling studies.
- Performed shRNA knockdown studies to validate ERG as a tractable in vivo target; collaborated closely with internal biology and chemistry functions to drive decision-making.
- Established and executed PDX efficacy studies in collaboration with external CRO partners to evaluate translational potential of lead candidates.
- Contributed to study design, protocol development, vendor management, and data QC/review to ensure preclinical rigor and alignment with program goals.
- Regularly presented data and strategy updates in monthly program team meetings, pharmacology subteam meetings, and internal cross-functional reviews.
Associate Scientist I
Parabilis Medicines (Formerly FogPharma)
Cambridge, MA
03.2022 - 03.2024
- Supported IND-enabling studies for FOG-001, contributing to PK/PD, efficacy, and MTD study execution in CDX models across multiple tumor types.
- Performed qPCR-based biomarker analysis on ex vivo tissues to characterize treatment response and downstream gene modulation.
- Contributed to preclinical study design, data analysis, and protocol/report preparation in support of regulatory submission.
- Trained and mentored junior team members in animal handling, dosing, sample collection, and GLP-aligned workflows.
In-Vivo Toxicology Research Technician
Charles River Laboratories
Shrewsbury, MA
06.2021 - 03.2022
- Collected and reported accurate study data under minimal supervision in accordance to study protocols and GLP.
- Performed blood collections and administered test articles in GLP studies using various techniques in mice, rats, canines, and non-human primates.
- Monitored animal health and welfare via cage side observations and detailed clinical examinations.
- Managed multiple studies concurrently as designated lead technician, collaborating with Study Directors and research staff.
Laboratory Animal Technician Intern
AbbVie Inc.
Worcester, MA
06.2017 - 08.2020
- Performed daily animal care including enrichment and well-being practices.
- Conducted aseptic techniques for equipment sterilization and surgical support.
- Recorded environmental parameters and maintained compliance with SOPs and AAALAC standards.
Education
Bachelor of Science - Biology, Foundations of Medical Science (FMS), Human or Veterinary
Elon University
Elon, North Carolina05.2021
Skills
- In vivo pharmacology
- PK/PD modeling
- Ex vivo techniques (qPCR, Western Blot, ELISAetc)
- CDX/PDX model development/validation
- GraphPad Prism, Microsoft Excel/PowerPoint/Word
- GLP compliance
- Data presentation
- External collaboration
- Tumor modeling
- Cell culture
- Electronic lab notebook documentation
Timeline
Senior Associate Scientist
Parabilis Medicines (Formerly Fog Pharma)
03.2026 - Current
Associate Scientist II
Parabilis Medicines (Formerly FogPharma)
03.2024 - Current
Associate Scientist I
Parabilis Medicines (Formerly FogPharma)
03.2022 - 03.2024
In-Vivo Toxicology Research Technician
Charles River Laboratories
06.2021 - 03.2022
Laboratory Animal Technician Intern
AbbVie Inc.
06.2017 - 08.2020
Bachelor of Science - Biology, Foundations of Medical Science (FMS), Human or Veterinary
Elon University
2025 Parabilis Values Award Recipient
Recipients receive this award as recognition of exceptional commitment to embodying the company's core values of Growth-Minded, In(ter)dependent, Patient-Focused, and All-In