Summary
Overview
Work History
Education
Skills
Certification
Timeline
background-images

Jack Barresi

SAN DIEGO,CA

Summary

Detail-oriented Process Development Chemist with 3+ years of hands-on experience in oligonucleotide purification, analytical testing (HPLC), cGMP manufacturing, and process optimization. Skilled in chromatography (AKTA systems, FineLINE columns), organic synthesis (AKTA Oligopilot), and process documentation (SOP revisions, change control). Lean Six Sigma Yellow Belt certified with a proven track record of improving manufacturing workflows and cross-functional collaboration.

Overview

3
3
years of professional experience
1
1
Certification

Work History

Process Development Chemist

Hologic
08.2022 - Current
  • Purify large-scale and small-scale oligonucleotides using AKTA Pilot and Pure chromatography systems.
  • Operate Cytiva FineLINE columns (35, 70) and manage ion-exchange media packing/unpacking.
  • Troubleshoot manufacturing issues; initiate change control procedures to update SOPs and optimize workflows.
  • Analyze oligonucleotide quality with HPLC systems (Vanquish, Ultimate 3000) under cGMP guidelines.
  • Collaborate with Document Control and Quality Engineering to revise, update, and obsolete procedures.
  • Perform oligonucleotide synthesis using AKTA OligoPilot automated synthesizers.
  • Drive process improvements through Lean Six Sigma practices and cross-functional collaboration.

Research Associate

Hologic
03.2022 - 08.2022
  • Conducted RT-PCR and RT-TMA assays using the Panther Fusion System.
  • Applied aseptic techniques for pipetting, decontamination, and equipment maintenance.
  • Analyzed large datasets using JMP and Microsoft Excel; ensured data integrity and compliance.
  • Properly handled and disposed of hazardous reagents following lab safety protocols.

Clinical Laboratory Technician

Sequenom
11.2021 - 03.2022
  • Operated PCR assay equipment (Kingfisher Flex, Hamilton Microlab STAR) for routine testing.
  • Trained new staff in reagent preparation, aliquoting, and RNA amplification protocols.
  • Managed specimen logs, ensured quality control compliance, and maintained freezer inventory.

Education

Bachelor of Science - Biology

San Diego State University
05.2019

Skills

  • AKTA Pilot / AKTA Pure Systems
  • Oligonucleotide Purification
  • Organic Synthesis
  • HPLC Analysis (Vanquish, Ultimate 3000)
  • UNICORN Software
  • CGMP Compliance / Change Control
  • Microsoft Excel
  • Process Optimization
  • Cross-Departmental Communication
  • Troubleshooting & Root Cause Analysis
  • SOP Writing and Revision
  • Kingfisher Flex / Hamilton Microlab STAR

Certification

Lean Six Sigma Yellow Belt

Timeline

Process Development Chemist

Hologic
08.2022 - Current

Research Associate

Hologic
03.2022 - 08.2022

Clinical Laboratory Technician

Sequenom
11.2021 - 03.2022

Bachelor of Science - Biology

San Diego State University

Similar Profiles

CREATE PROFILE
Jack Barresi