Jack Papetti
Cambridge,MA
Summary
Accomplished Senior Research Associate with extensive expertise in cellular assays and mammalian cell culture, recognized for driving high-impact research projects. Proven track record in data capture procedures and action planning, demonstrating strong organizational skills and critical thinking. Successfully led complex studies from inception to completion, significantly contributing to team goals and scientific advancements. Committed to leveraging knowledge in project management and data analysis to foster innovation in future research endeavors.
Overview
6
6
years of professional experience
Work History
Senior Research Associate I, Biology Group
RELAY THERAPEUTICS
Cambridge, MA
12.2023 - Current
- Company Overview: NASDAQ: RLAY
- NASDAQ: RLAY
Research Associate I
RELAY THERAPEUTICS
Cambridge, MA
05.2021 - 12.2022
- Company Overview: NASDAQ: RLAY
- Led an enzymatic assay optimization and screening campaign, assessing internal and competitor compounds for activity rescue across 70+ patient mutations
- Valued at $1.5M by contractor
- Conducted a proliferation assay screening campaign of 400+ compounds across 6 cancer cell lines, identifying a clinical candidate
- Authored the IND application section for this assay
- Implemented an RNAseq workflow for the biology group, coordinating sample prep, QC, amplification, sequencing, and analysis across two sites
- Collaborated with 8 cross-functional coworkers, reducing costs by 35% and turnaround time by 3 weeks compared to contractor offer
- Developed a biomarker assay with an external contractor to assess target inhibition, overseeing the screening of 500+ compounds
- Improved efficiency, saving 5 additional hours/week for mechanistic studies
- Led a bi-weekly working group for wet lab biologists to troubleshoot experiments, share techniques, and align on project goals
- Facilitated the introduction of 4 assays, feedback on 6 experiments, and growth opportunities for 3 quieter members
- NASDAQ: RLAY
Research Intern
DANA FARBER CANCER INSTITUTE, NOVINA LAB
Boston, MA
01.2020 - 12.2020
- Conducted laboratory research independently during COVID-19 pandemic to screen drug candidates against an oncogenic lncRNA-protein interaction with industry collaborator
- This is a responsibility bullet
- Do you have an accomplishment bullet here
Research Intern
MARINE BIOLOGICAL LABORATORY, ECHEVERRI LAB
Woods Hole, MA
01.2019 - 12.2019
- Performed laboratory research to characterize micro-RNA regulated regulation of spinal cord regeneration of axolotl salamander through tissue dissection and analysis
- Another responsibility bullet
Education
B.A. - Biology, Economics
BROWN UNIVERSITY
PROVIDENCE, RI01.2021
Skills
- Mammalian cell culture
- Cellular assays
- Tissue processing for nucleic acid extraction
- RT-qPCR
- Bulk RNA-seq
- Western blot
- Cell engineering
- Plasmid design and preparation
- Immunofluorescence
- Confocal imaging
- Preprocessing
- Quality control
- Primary analysis of bulk RNAseq data
- Flow cytometer operation
- Sample preparation
- Dissection
- Cryosectioning of organs
Timeline
Senior Research Associate I, Biology Group
RELAY THERAPEUTICS
12.2023 - Current
Research Associate I
RELAY THERAPEUTICS
05.2021 - 12.2022
Research Intern
DANA FARBER CANCER INSTITUTE, NOVINA LAB
01.2020 - 12.2020
Research Intern
MARINE BIOLOGICAL LABORATORY, ECHEVERRI LAB
01.2019 - 12.2019
B.A. - Biology, Economics
BROWN UNIVERSITY