Jacques C. Mbongue

Results-oriented writer with experience preparing concise and accurate technical documents. Expert at delivering high-quality work within tight deadlines. Talented individual collaborates with cross-functional teams for accuracy and clarity of technical content. Organized and dependable candidate successful at managing multiple priorities with a positive attitude. Willingness to take on added responsibilities to meet team goals.

• BI 451 (Special Topics in Biology)
• This is a survey of a specified topic in biology, from its basics to its application
• Here we delve in depth into the immunological concepts of vaccines and its various applications in infectious and autoimmune disease therapies
• PE 350 (Pharmacology for Health Professions)
• An integrative course of study that applies the relevant information of all medical sciences to the treatment of disease
• Throughout this class the essential background information of anatomy, physiology, and pathology required for an understanding of drug action is reviewed
• The major focus of this class is to provide an understanding of the mechanisms of action, main therapeutic effects, clinical uses, and adverse reactions of drugs
• Diagnostic Methods - Immunological Diagnosis, Diagnostic Methods - Microbiological
• Diagnosis
• Diagnostic Methods - Molecular Diagnosis, Diagnostics - Laboratory, Good
• Clinical Practices - Adverse Events
• Good Clinical Practices
• Informed Consent
• Managing Clinical Supplies, Good Clinical Practices - Monitoring, and Good
• Manufacturing Practices
• Documentation and Record Keeping
• Good Manufacturing Practices
• Pharmaceutical CAPAs
• Microarray - Affymetrix, Microarray - Affymetrix GeneChip Operating Software, Microarray
• AmpliChip, Microarray - CaSNP, Microarray Cell-Free Protein Array, Microarray -
• Cellular Microarrays, Research and Analysis
• Company Research, Research and Analysis Competition Analysis
• Big Data, Data Analysis
• Liquid Biopsy, Processing Human Sera
• RNA Isolation, cDNA Synthesis, qPCR, Immunoblotting Bacterial Transformation, Plasmid
• Transfection, siRNA Transfection, Flow Cytometry, Cell Culture
• Molecular Drug Targeting
• Autoimmunity Research.

1. Mbongue, J.C.; Vanterpool, E.; Langridge, W.H.R. Exploring the Potential of Plant-Based
CTB-INS Oral Vaccines in Treating Type 1 Diabetes. Immuno 2023, 3(2), 217-227. https://doi.org
/10.3390/immuno3020014.
2. Mbongue, J.C.; Vanterpool, E.; Firek, A.; Langridge, W.H.R. Lipopolysaccharide-Induced
Immunological Tolerance in Monocyte-Derived Dendritic Cells. Immuno 2022, 2, 482-500.
https://doi.org/10.3390/immuno2030030
3. Channakeshava Sokke Umeshappa, Jacques C. Mbongue, Santiswarup Singha, Saswat
Mohapatra, Jun Yamanouchi, Justin A. Lee, Roopa Hebbandi Nanjundappa, Kun Shao, Urs
Christen, Yang Yang, Kristofor K Ellestad, Pere Santamaria (2020) Ubiquitous antigen-specific
T-regulatory type 1 cells variably suppress hepatic and extra-hepatic autoimmunity. The
Journal of Clinical Investigation. https://www.jci.org/articles/view/130670
4. Jacques C. Mbongue, Ali R Alhoshani, Jeffrey Rawson, Pablo Antonio Garcia, Nelson
Gonzalez, Kevin Ferreri, Fouad Kandeel and Mohamed Ibrahim Husseiny (2020) Tracking of oral
Salmonella-based vaccine for type 1 diabetes in non-obese diabetic mice.
https://www.frontiersin.org/articles/10.3389/fimmu.2020.00712/abstract Frontiers
Immunology.
5. Mbongue JC, Rawson J, Garcia PA, Gonzalez N, Cobb J, Kandeel F, Ferreri K and Husseiny MI
(2019)Reversal of New Onset Type 1 Diabetes by Oral Salmonella-Based Combination Therapy
and Mediated by Regulatory T-Cells in NOD Mice. Front. Immunol. 10:320. Doi: https://doi.org
/10.3389/fimmu.2019.00320
6. Husseiny, M.I. Weiting Du, Mbongue J., Lenz A., Rawson, J. Kandeel, F. Ferreri, K. (2018)
Factors affecting Salmonella-based Combination Immunotherapy for Prevention of Type 1  diabetes in Non-obese Diabetic Mice. Vaccine, Volume 36, Issue 52 https://doi.org/10.1016
/j.vaccine.2018.10.10
7. Mbongue, J. C., Nieves, H. A., Torrez, T. W, and Langridge, W. H. R. (2017).The Role of Dendritic
Cell Maturation in the Induction of Insulin- Dependent Diabetes
Mellitus(2017)Front.Immunology3:827.doi:http://journal.frontiersin.org/article/10.3389
/fimmu.2017.00327/full
8. Mbongue, J. (2016) Mechanism of Chimeric Vaccine Mediated Immune Suppression of Human
Dendritic Cells. https://scholarsrepository.llu.edu/etd/348/
9. Kim, N.-S., Mbongue, J. C., Nicholas, D. A., Esebanmen, G. E., Unternaehrer, J. J., Firek, A.F., &
Langridge, W. H. R. (2016). Chimeric Vaccine Stimulation of Human Dendritic Cell Indoleamine
2, 3- Dioxygenase Occurs via the Non-Canonical NF- κB Pathway. PLoS ONE,11(2), e0147509.
10. Mbongue, J. C., Nicholas, D. A., Torrez, T. W., Kim, N.-S., Firek, A. F., & Langridge, W. H. R.
(2015).The Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and Autoimmunity.
Vaccines,3(3), 703–729. http://doi.org/10.3390/vaccines3030703
11. Mbongue, J. C., Nicholas, D. A., Zhang, K., Kim, N.-S., Hamilton, B. N., Larios, M., Langridge,
W. H. R. (2015).Induction of Indoleamine 2, 3- Dioxygenase in Human Dendritic Cells by a
Cholera Toxin B Subunit—Proinsulin Vaccine. PLoS ONE, 10(2), e0118562. http://doi.org/10.1371
/journal.pone.0118562
12. Jacques Mbongue, Dequina Nicholas, Anthony Firek, and William Langridge. The Role of
Dendritic Cells in Tissue-Specific Autoimmunity. Journal of Immunology Research, vol. 2014,
Article ID857143, 17 pages, 2014. doi:10.1155/2014/857143.

1. Arrest in the Progression of Type 1 Diabetes at the Mid-Stage of Insulitic Autoimmunity Using an Autoantigen-Decorated All-trans Retinoic Acid and Transforming Growth Factor Beta-1 Single Microparticle Formulation.

Front. Immunol., 08 March 2021
Sec. Antigen Presenting Cell Biology
Volume 12 - 2021 | https://doi.org/10.3389/fimmu.2021.586220

2. Significance of pyroptosis-related gene in the diagnosis and classification of rheumatoid arthritis.

Front. Endocrinol., 15 March 2023
Sec. Cancer Endocrinology
Volume 14 - 2023 | https://doi.org/10.3389/fendo.2023.1144250