Joby Jose
Pasadena,USA
Summary
Accomplished analytical chemist with extensive experience at Huntington Medical Research Institutes, specializing in method development and validation using HPLC and LC-MS/MS. Proven leadership in mentoring junior scientists and delivering actionable recommendations, ensuring compliance with GMP standards while driving innovative research in nutraceuticals and functional foods.
Overview
17
17
years of professional experience
Work History
Postdoctoral fellow
Huntington Medical Research Institutes
Pasadena, USA
01.2023 - Current
Research Associate, Analytical Chemistry
KRIBS-BIONEST, Rajiv Gandhi center for Biotechnology
Kochi, India
01.2019 - 01.2023
- Give support to nutraceutical, cosmeceutical, and functional food start-ups in research project design, experimentation, data collection, and analysis.
- Provide analytical support to nutraceutical companies by performing purity testing of dietary supplements using HPLC and LC-MS/MS, including products derived from herbal extracts, polyphenol-rich functional foods, medicinal foods, and spices.
- Deliver technical expertise to biotechnology start-up enterprises across multiple instrumentation platforms, including analytical chemistry, phytochemistry, DNA sequencing, tissue culture, and downstream processing.
- Method development, optimization and validation of new assays using high-end analytical equipment like LC-MS/MS, GC, and HPLC.
- Troubleshoot and ensure proper maintenance, calibration, and documentation for instruments including genetic analyzer, real-time PCR, ELISA readers, lyophilizer, rotor evaporators, pilot spray dryer, and UV-Visible spectrophotometers.
- Ensure laboratory operations under strict cGMP and GDP during all analytical and research activities.
Laboratory Officer
Thyrocare Technologies Ltd.
Navi Mumbai, India
01.2018 - 01.2019
- Manage daily laboratory operations, including quality assurance (QA), quality control (QC), and proficiency testing. Supervise and support a team of laboratory technicians.
Research Scholar
Kannur University
Kerala, India
01.2011 - 01.2018
Senior Research Fellow (SRF)
AdityaKiran College of Applied Studies
Kannur, India
01.2010 - 01.2011
Junior Research Fellow (JRF)
Mar Athanasios College for Advanced Studies
Kerala, India
01.2009 - 01.2010
Education
Ph.D. - Biochemistry (Phytochemistry)
Kannur University
India01.2018
M.Sc. - Biochemistry
Bharathiar University
India01.2008
B.Sc. - Chemistry
MG University
India01.2006
Skills
- Chromatography
- Targeted Mass Spectrometry
- HPLC
- GC
- HPTLC
- Data acquisition and processing
- Analyst
- Chromeleon
- Xcalibur
- Spectroscopy
- FTIR
- UV-Visible
- NMR data interpretation
- Molecular techniques
- Genetic analyzer
- Gene sequencing
- PCR
- RT-PCR
- ELISA
- Herbal Extraction & Purification
- Soxhlet extraction
- Rotary evaporation
- Column chromatography
- GMP
- QA
- QC
- Method validation
- SOP development
- Analytical reports
- Regulatory documentation
- Data Analysis & Reporting
- Statistical analysis
- Interpretation of complex analytical data
- Technical reports
- Scientific publications
- Actionable recommendations
- Leadership
- Mentoring junior scientists
- Method transfer
- Troubleshooting
- Software & Data Analysis
- LIMS
- GraphPad Prism
- MetaboAnalyst
- Reactome
- ShinyGO
- Biosafety & Laboratory Practices
- Project & Team Skills
- Multidisciplinary teams
- Project organization
- Cross-functional communication
- Scientific presentations
Summary Of Qualifications
- Postdoctoral training (Topic: Analytical method development for the sensitive detection of biomarkers in cognitive decline associated with Alzheimer's disease)., Development of sensitive LC-MS/MS method, optimization and validation for the sensitive analysis of metabolites associated with cognitive decline in Alzheimer's disease., Develop improved strategies for the sensitive detection of metabolites using tandem mass spectrometry., Analyze the effectiveness of nutraceuticals like omega-3 fatty acids supplementation in cognitive health using LC-MS/MS., Provide hands-on training and mentorship to students on analytical method development, and data interpretation.
- Doctoral program (Topic: Studies on anti-carcinogenic properties of selected flavonoids and their bioavailability and biodegradation)., Extraction, isolation and purification of polyphenols from therapeutic plants including Aloe vera, Mimosa pudica and Phyllanthus niruri using Soxhlet extraction, rotary evaporation, and column chromatography., Characterization of bioactive compounds from polyphenol extracts using HPTLC, UV Visible, FTIR, NMR and LC-MS techniques., Evaluation of the therapeutic potential and bioactivity of purified polyphenol extracts through in-vitro and in-vivo methods.
Core Technical Expertise
Targeted Mass Spectrometry (LC-MS/MS), HPLC, GC, HPTLC, Analyst (Sciex), Chromeleon, Xcalibur (Thermo Scientific), FTIR, UV-Visible, NMR data interpretation, Genetic analyzer (gene sequencing), PCR, RT-PCR, ELISA, Soxhlet extraction, rotary evaporation, column chromatography, Method validation, SOP development, analytical reports, regulatory documentation, Statistical analysis, interpretation of complex analytical data, technical reports, scientific publications, actionable recommendations, Mentoring junior scientists, method transfer, troubleshooting
Timeline
Postdoctoral fellow
Huntington Medical Research Institutes
01.2023 - Current
Research Associate, Analytical Chemistry
KRIBS-BIONEST, Rajiv Gandhi center for Biotechnology
01.2019 - 01.2023
Laboratory Officer
Thyrocare Technologies Ltd.
01.2018 - 01.2019
Research Scholar
Kannur University
01.2011 - 01.2018
Senior Research Fellow (SRF)
AdityaKiran College of Applied Studies
01.2010 - 01.2011
Junior Research Fellow (JRF)
Mar Athanasios College for Advanced Studies
01.2009 - 01.2010
Ph.D. - Biochemistry (Phytochemistry)
Kannur University
M.Sc. - Biochemistry
Bharathiar University
B.Sc. - Chemistry
MG University