Julia Teresa Garcia-Daou
Sunnyvale,CA
Summary
Results-oriented Scientist with ten years of experience leading successful research, development, and validation projects. Proven ability to effectively communicate and collaborate with multidisciplinary teams. Expertise in sequencing technologies and a strong background in IVD product development.
Overview
11
11
years of professional experience
Work History
Development Scientist II – R&D
Freenome
12.2021 - Current
- Managed cross-departmental projects for assay development and validation, ensuring timely execution
- Facilitate collaborative meetings with stakeholders to drive project progress
- Develop and execute rigorous protocols for the analytical validation of cancer screening test
- Performed data analysis, summarized findings, and presented key outcomes to stakeholders
- Generated comprehensive reports adhering to regulatory and quality guidelines
Development Scientist I – R&D
Freenome
03.2020 - 12.2021
- Spearheaded cost-reduction initiatives by leading the planning and testing of strategies to optimize product development expenses
- Developed and optimized assays on automated platforms
- Streamlined operations by coordinating interdepartmental teams for the development and testing of automated processes
- Conducted NGS projects by designing experiments, planning execution, analyzing data, and drawing conclusions
Graduate Student - Genetics
Stanford University School of Medicine
06.2014 - 12.2019
- Ph.D Thesis: Characterization of the Long Noncoding RNA Dino in the DNA Damage Response
- Successfully led a collaborative research effort involving six scientists, resulting in the publication of our research in the top journal, Nature Genetics
- Characterized the role of the lncRNA Dino in p53-dependent cellular responses using a diverse range of molecular biology techniques, including RT-qPCR, cloning, RNA-seq, ATAC-seq, and in-depth data analysis
- Investigated the in vivo consequences of Dino loss using two independent mouse knockout models
- Designed and performed single-cell studies using10x platform, Fluidigm, and RT-qPCR
- Presented research findings at both local and international conferences through oral and poster presentations
Research Intern – Translational Oncology
Genentech
06.2017 - 09.2017
- Designed and executed a drug discovery study utilizing the company's existing small molecule libraries
- Conducted semi-high throughput screening to identify potential therapeutic small molecules
- Analyzed chromatin accessibility data that significantly contributed to a published scientific manuscript
Education
Ph.D. - Genetics
Stanford University
01.2020
Ignite Certificate Program - Innovation and Entrepreneurship
Stanford Graduate School of Business
01.2018
B.S. - Biochemistry
University of California, Los Angeles
01.2013
Skills
- Project management: resource and time management, coordination, project tracking, and cross-functional leadership
- Assay development: Assay development, optimization, and automation (liquid handlers) Study design, protocol and report writing, and data analysis
- NGS: Library preparation, ATAC-seq (chromatin accessibility assay), RNA-seq, and target capture
- Single Cell: Single-cell capture by microfluidics,10x platform, and single-cell RT-qPCR
- Molecular biology: General molecular biology techniques, including qPCR, site-directed mutagenesis, immunofluorescence, ChIP, western blot, and molecular cloning
- Cell biology: General cell biology techniques, including mammalian cell culture and cell cycle analysis
- Computational: Data analysis in R and some Python Statistical analysis in Excel and professional
Publications
- Schmitt, A.M.*, Garcia, J.T.*, Hung, T.* et al. An inducible long noncoding RNA amplifies DNA damage signaling. Nature Genetics,2016. *These authors contributed equally
- Griffin MF, Borrelli MR, Garcia JT, et al. “JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models.” Science translational medicine,2021
- Pribluda, A., [...], Garcia, J.T., et al. EHMT2 methyltransferase governs cell identity in the lung and is required for KRASG12D tumor development and propagation. eLIFE,2022
- Leavitt, T., [...], Garcia, J.T., et al. Prrx1 Fibroblasts Represent a Pro-fibrotic Lineage in the Mouse Ventral Dermis. Cell Reports,2020
- Borrelli, M.R., Garcia, J.T., et al. JUN Drives Pathologic Scarring by Activating Key Fibroproliferative Pathways in Fibroblast Subpopulations. Journal of the American College of Surgeons,2019
- Pribluda, A., [...], Garcia, J.T., et al. G9a Methyltransferase Governs Cell Identity in the Lung and is Required for KRAS G12D Tumor Development and Propagation. BioRxiv,2020
PATENTS
“RNA Replication Using Transcription Polymerases” - US Patent App.17/624,782 - Date of publication: Aug18,2022
Awards
National Institutes of Health (NIH) Research Diversity Supplement 2017-2019
National Science Foundation (NSF) Graduate Research Fellowship 2014-2017
Howard Hughes Medical Institute-EXROP Research Fellowship 2012-2013
NIH-MARC Research Fellowship 2011-2013
ACS Scholar by American Chemical Society 2010-2013
Awards and Fellowships
National Institutes of Health (NIH) Research Diversity Supplement
National Science Foundation (NSF) Graduate Research Fellowship
Howard Hughes Medical Institute-EXROP Research Fellowship
NIH-MARC Research Fellowship
ACS Scholar by American Chemical Society
Timeline
Development Scientist II – R&D
Freenome
12.2021 - Current
Development Scientist I – R&D
Freenome
03.2020 - 12.2021
Research Intern – Translational Oncology
Genentech
06.2017 - 09.2017
Graduate Student - Genetics
Stanford University School of Medicine
06.2014 - 12.2019
Ignite Certificate Program - Innovation and Entrepreneurship
Stanford Graduate School of Business
Ph.D. - Genetics
Stanford University
B.S. - Biochemistry
University of California, Los Angeles
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