KAMAI PATTERSON
Silver Spring,MD
Summary
Preclinical research scientist with 3 years of experience in immunology and translational research, specializing in in vitro modeling of therapeutic mechanisms and assay development. Strong background in experimental design, scientific writing, and data analysis. Experienced in developing research protocols, conducting literature reviews, and analyzing molecular and cellular responses to therapeutic interventions. Exposure to in vivo research environments, including animal handling and surgical workflows, with a demonstrated ability to transition into preclinical research settings.
Overview
8
8
years of professional experience
Work History
ORISE Fellow
Food and Drug Administration (FDA)
Silver Spring, USA
01.2023 - Current
- Designed and executed immunological assays (ADCC, ADCP) to evaluate antibody-mediated cellular responses and therapeutic mechanisms.
- Analyzed molecular and cellular responses to therapeutic antibodies, including Fc receptor binding and CTLA-4 expression, to support mechanistic research.
- Collaborated with interdisciplinary research teams to refine methodologies, resulting in improved assay performance.
- Developed experimental protocols and authored SOPs, enhancing reproducibility and ensuring regulatory compliance in laboratory workflows.
- Conducted literature reviews and synthesized scientific findings to shape experimental design and support ongoing research initiatives.
- Performed flow cytometry experiments and analyzed multi-parameter datasets using FlowJo to quantify immune cell populations and phagocytic activity.
- Maintained human monocytic cell lines (U937, THP-1) and performed PBMC isolation for immunological assays.
- Collected, managed, and analyzed experimental data using Excel and scientific documentation practices.
- Trained laboratory personnel on experimental procedures and data collection techniques.
COVID-19 Site Lead / Technician
Nomi Health
09.2021 - 03.2022
- Implemented quality assurance procedures and analyzed operational data, leading to improved testing accuracy and streamlined workflow.
- Managed high-volume diagnostic testing operations, ensuring compliance with health and safety protocols.
- Supervised staff, coordinating workflow to enhance operational effectiveness in a high-demand clinical setting.
Student Research Intern
University of Arkansas for Medical Sciences
06.2018 - 08.2018
- Conducted in vivo experiments with murine models to evaluate neurological impacts of radiation exposure.
- Maintained tissue culture cell lines and performed PCR, mRNA extraction, and DNA analysis to support ongoing research.
- Collected and analyzed experimental data, contributing to advancements in neuroscience research.
Preclinical Research Exposure (Animal & Surgical Observation)
- Acquired skills in aseptic technique and surgical instrumentation, contributing to effective experimental study design in animal models.
- Engaged in research evaluating physiological and neurological outcomes, providing insights into animal model responses.
- Observed animal handling and preclinical research procedures, enhancing understanding of murine studies and surgical workflows.
- Developed foundational understanding of IACUC protocols and ethical considerations in animal research.
Education
Bachelor of Science - Biology
Jackson State University
Skills
- Preclinical research
- Experimental design
- Immunological assays
- Flow cytometry
- Cell culture
- Data analysis
- Scientific writing
- SOP development
- Mechanism analysis
- Project coordination
Relevant Project Experience
- Development of ADCC and ADCP assays for evaluation of immune checkpoint inhibitors.
- Mechanistic evaluation of antibody-mediated immune responses.
- Research involving amyloid beta (Aβ) and antibody-mediated phagocytosis in neurodegenerative disease models.
- Analysis of molecular responses to therapeutic interventions.
Timeline
ORISE Fellow
Food and Drug Administration (FDA)
01.2023 - Current
COVID-19 Site Lead / Technician
Nomi Health
09.2021 - 03.2022
Student Research Intern
University of Arkansas for Medical Sciences
06.2018 - 08.2018
Preclinical Research Exposure (Animal & Surgical Observation)
Bachelor of Science - Biology
Jackson State University