KAMALA ANUMUKONDA
Edison,NJ
Summary
Molecular immunologist and physician with 15+ years of experience in pre-clinical drug discovery, specializing in immunology and cancer research. Expertise in advising and developing Artificial Intelligence/Machine learning models and Augmented Reality/Virtual Reality solutions for the healthcare industry in collaboration with partners.
Overview
20
20
years of professional experience
1
1
Certification
Work History
Investor & Advisor
DataNimbus
07.2024 - Current
- Provide subject matter expertise and regulatory compliance guidelines for the development and use of Artificial Intelligence & Machine learning models in clinical trials.
Partner & Lead Consultant
Anuko Tech Inc
11.2023 - Current
- Leading consulting agency providing subject matter expertise in Healthcare and Life sciences
- Working on AR, VR, MR and medical animation and illustration projects for Medical training and Education.
Senior Scientist
Skunkworx Bio
11.2021 - 10.2023
- Preclinical Drug discovery- Lead discovery and Project management
- Used phage display technology as a platform to discover novel pocket biologics both peptides and antibodies, validated them using in vitro assays and developed data packages and presentations of pre-clinical studies
- The targets included oncology (breast, lung, pancreatic cancers) and viral infectious diseases
- Responsibilities included conducting phage display assays to identify novel peptide/ antibody binders using proprietary libraries
- Developed cloning strategies and expression studies in bacterial and mammalian cells
- Validated the targets identified by phage display using in vitro assays/ cell cultures and Flow cytometry
- Modeled de novo proteins using Cyrus CAD
- Studied protein- protein interactions using molecular modeling software PIPER docking
- Developed the complete data package and communicated the findings to cross functional teams involved in the in vivo studies/ VP of strategic development at biweekly meetings
- Developed platform technology and scientific statements for two provisional patents and communicated with patent lawyer teams
- Trained and educated other scientists in molecular techniques and cell culture
- Generated and interpreted scientific data, developed publication strategies for both in house use as well as patents and publications
- Contributed to the timely release of data supporting core development areas.
Post-Doctoral Fellowship
SUNY, Downstate Medical center
01.2017 - 12.2019
- Discovered new Single domain antibody genes in elephant fish with unique CDR3 repertoire and published the findings
- Responsibilities included using molecular cloning techniques to discover novel immunoglobulin molecules (single chain antibodies)
- Designed, executed, and interpreted DNA sequence data for cloning experiments
- Facilitated coordination with external teams on collaborative projects and developed protocols for optimization of molecular biology assays
- Used statistical analysis GraphPad prism/Microsoft excel to generate publication ready data
- Presented PowerPoints and posters at lab meetings and co-authored publications.
Doctoral Research
SUNY, Downstate Medical Center
01.2009 - 01.2016
- Discovered critical roles of transcription factors in B lymphocyte and Macrophage development and function
- The study focused on the genetic deletion/ inactivation of MiT family of transcription factors and its effect on both adaptive and innate immune responses
- Used in vitro and in vivo mouse models to study immune responses to inflammation and performed cytokine assays for immunoglobulin molecules
- Used in vitro and in vivo phagocytosis assays to study immune cell function
- Used flow cytometry staining to characterize various B cell/Macrophage phenotypes and analyzed the data using cell quest/Flo Jo and GraphPad prism
- Trained masters’ students and medical students in molecular biology and immunology
- Presented PowerPoints and posters at lab meetings and annual research day.
Tutor
CW post campus LIU
01.2007 - 01.2008
- Provided tutoring services to bachelor’s students in Biology, Physics and Chemistry as a part of the peer tutoring services on campus.
Medical Consultant (Doctor)
Ruby Hall Clinic – Neuro Trauma Unit
07.2006 - 12.2006
- Provided medical care for critically ill neuro trauma patients suffering cerebrovascular injuries and head trauma.
Medical Consultant (Doctor)
St. Josph Dental College
01.2006 - 06.2006
- Provided out-patient care at St
- Joseph's primary care clinic
- Taught General Medicine to BDS students.
Junior Doctor
King George Hospital
01.2005 - 12.2005
- Provided medical care to both in-patients and out-patients at KGH and satellite hospitals in various departments including general medicine, general surgery, orthopedics, pediatrics, ophthalmology, blood banking and gynecology and obstetrics.
Education
Ph.D. - Doctor of Philosophy in Cell & Molecular Biology
State University of New York, Downstate Medical Center
Brooklyn, NY12.2016
Master of Science - Medical Biology
Long Island University CW Post
Brookville, NY05.2009
MBBS - Bachelor of Medicine and Bachelor of Surgery
NTR University of Health Sciences, Andhra Medical College
Visakhapatnam12.2005
Skills
- Drug Discovery
- Computational modeling
- Medical Education
- Research and Development
- Compliance requirements
- Strategic Planning
- Analytical Thinking
- Attention to Details
- Teamwork and rapid prototyping
- Interdisciplinary Collaboration
- Presentations and public speaking
- Project and Program Management
Patents
- BIFUNCTIONAL ANTI-PATHOGENIC AGENTS, SKX-005PC/114358-5031
- BIFUNCTIONAL IMMUNE MODULATING AGENTS, SKX-005PC/114358-5032
Certification
- Breaking into MSL career- The MSL candidate presentation and communication skills training program- Oct 2021 awarded by the MSL society
- CLRA Certified Tutor- 2007-2009
Affiliations
- AMERICAN ASSOCIATION OF IMMUNOLOGISTS, TRAINEE MEMBER
- MEDICAL SCIENCE LIAISON SOCIETY
- THE ENVIRONMENTAL SUSTAINABILITY ROTARY ACTION GROUP
Languages
English
Full Professional
Telugu
Native or Bilingual
Hindi
Full Professional
Awards
- Dean’s award for Academic Excellence, Long Island University CW Post, May 2009
- Travel award for poster presentation, SUNY Downstate Medical Center, April 2015
Publications
- Single Domain Antibody Genes in Fish Selected to Generate Unique CDR3 Repertoire, Kamala Anumukonda, Malcolm Francis, Peter Currie, Frank Tulenko, and Ellen Hsu, Eur J Immunol, 52, 2, 247-260, 10.1002/eji.202149588, 2022 Feb
- Mitf regulates gene expression networks implicated in B cell homeostasis, germinal center responses, and tolerance, Abhimanyu Amarnani, Maria Lopez-Ocasio, Ramile Dilshat, Kamala Anumukonda, Jonathan Davila, Nikita Malakhova, Chongmin Huan, Erna Magnusdottir, Eirikur Steingrimsson, Christopher Roman, Frontiers in Immunology, Manuscript approved, 2024
- Discovery of a human TIM-4 blocking antibody using directed-protein engineering shows anti-tumor effects in a syngeneic colon cancer mouse model, Karla K. Frietze, Kamala Anumukonda, Laura Padula, Natasha Strbo, and Neil Goldstein, BMC cancer, Manuscript submitted
- Role of TFEB in Macrophage Autophagy, Kamala Anumukonda, Chongmin Huan, Susan RS Gottesman, Christopher AJ Roman, Annual Research Day, SUNY Downstate Medical center, April 2015
Work Availability
monday
tuesday
wednesday
thursday
friday
saturday
sunday
morning
afternoon
evening
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Timeline
Investor & Advisor
DataNimbus
07.2024 - Current
Partner & Lead Consultant
Anuko Tech Inc
11.2023 - Current
Senior Scientist
Skunkworx Bio
11.2021 - 10.2023
Post-Doctoral Fellowship
SUNY, Downstate Medical center
01.2017 - 12.2019
Doctoral Research
SUNY, Downstate Medical Center
01.2009 - 01.2016
Tutor
CW post campus LIU
01.2007 - 01.2008
Medical Consultant (Doctor)
Ruby Hall Clinic – Neuro Trauma Unit
07.2006 - 12.2006
Medical Consultant (Doctor)
St. Josph Dental College
01.2006 - 06.2006
Junior Doctor
King George Hospital
01.2005 - 12.2005
Ph.D. - Doctor of Philosophy in Cell & Molecular Biology
State University of New York, Downstate Medical Center
Master of Science - Medical Biology
Long Island University CW Post
MBBS - Bachelor of Medicine and Bachelor of Surgery
NTR University of Health Sciences, Andhra Medical College
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