Karthika Harikumar Sangeetha

Developed expertise in regulatory requirements and compliance standards within the pharmaceutical industry, particularly in Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP).

Acquired hands-on experience in laboratory techniques, data collection, and data analysis for pharmacological research, including skills in drug formulation, pharmacokinetics, and both in vitro and in vivo testing.

Gained a comprehensive understanding of the drug development process, encompassing all stages from drug discovery through pre-clinical and clinical trials.

• Conducted comprehensive in silico research to investigate the therapeutic effects of sesquiterpenoids on the LGI1 protein, associated with Anti-Leucine-rich Glioma Inactivated-1 Autoimmune Encephalitis.
• Utilized molecular docking techniques to predict and analyze binding interactions between sesquiterpenoids and the LGI1 protein, evaluating potential therapeutic candidates.
• Performed molecular dynamics simulations to assess the stability and conformational changes of protein-ligand complexes, providing insights into the dynamic behavior of binding interactions over time.
• Contributed to the understanding of the molecular mechanisms underlying autoimmune encephalitis and explored novel treatment avenues through computational approaches.