Summary
Overview
Work History
Education
Skills
Publications
INTERNATIONAL PRESENTATION AND SCIENTIFIC MEETINGS
Affiliations
Licensure
Languages
Timeline
Generic
KHINE YIN MON

KHINE YIN MON

Cincinnati,OH

Summary

Research scientist with a medical degree and 4 years of postdoctoral research experience in reproductive biology, neuroendocrinology, ophthalmic research, and behavioral neuroscience. Expertise includes a range of techniques such as mouse models, molecular biology, imaging, behavioral assays, and advanced surgical methods. Proven ability in experimental design, data analysis, mentoring emerging scientists, and communicating complex scientific concepts effectively. Research focuses on 1)estrogen receptor signaling in reproductive pathology, 2)sexual differentiation of the brain, 3) maternal behavior, 4)infertility, and 5)ocular development.

Overview

12
12
years of professional experience

Work History

Postdoctoral Research Fellow

Department of Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati
Cincinnati
03.2022 - Current
  • Design, execute and analyze experiments to test hypotheses
  • Lead and manage research projects
  • Develop and implement new research initiatives and methodologies
  • Publish findings in peer-review journal
  • Manuscript writing, literature review
  • Reviewer: Biology of Reproduction journal
  • Mentored students, fostering skills development and enhancing lab productivity.

Assistant Professor

Department of Anatomy, Histochemistry and Cell Biology, Miyazaki University, Japan
Japan
01.2020 - 03.2020
  • Conducted laboratory experiments (molecular and cell biology including mouse experiments)
  • Data analysis, report and presentation
  • Grant writing, manuscript writing, literature review
  • Trained research skills to postgraduate students
  • Mentored medical students in histochemical techniques and cell biology concepts.

Project Researcher

Department of Obstetric and Gynecology, Tottori University, Faculty of Medicine, Japan
Japan
06.2019 - 12.2019
  • Conducted laboratory experiments (molecular and cell biology including mouse experiments)
  • Data analysis, report and presentation
  • Manuscript writing, literature review
  • Lectured to 5th grade medical students
  • Presented findings at national conferences, promoting knowledge sharing within the medical community.
  • Mentored junior researchers in research methodologies and ethical considerations in medical research.

Research Assistant/ Teaching Assistant

Department of Obstetric and Gynecology, Tottori University, Faculty of Medicine, Japan
Japan
04.2014 - 11.2018
  • Assisted seniors and supervisors in research and teaching
  • Conducted laboratory experiments (molecular and cell biology including mouse experiments)
  • Data analysis, report and presentation
  • Manuscript writing, literature review to support ongoing research projects in obstetrics and gynecology
  • Lectured to 5th grade medical students

Education

Ph.D. -

Department of Obstetric And Gynecology, Tottori University, Faculty of Medicine
Japan
01.2018

M.B.,B.S -

University of Medicine-2
Yangon, Myanmar
01.2012

Skills

    Animal handling and in vivo techniques

  • Mouse handling, colony management, and genotyping
  • Timed mating and breeding set up
  • Neonatal and adult mouse tissue collection
  • Estrous cycle monitoring and hormone administration
  • Anesthesia administration and post-operative care
  • Pre- and post-surgical monitoring
  • Mouse surgical techniques

  • Ovariectomy, temperature probe implantation, lens induced myopia induction, endometriosis induction
  • Tissue dissection and histological techniques

  • Brain, Eyes, reproductive tissues and other tissues collection (both neonatal and adult) and microdissection
  • Tissue embedding, cryosection
  • Histology and IHC/IF techniques
  • Confocal and fluorescence microscopy
  • Microscopy image analysis and quantification (Imaris, Image J)
  • Behavior assays in rodent models

  • Pup retrieval, Habituation/dishabituation tests
  • Reproductive behavior
  • Thermoregulation study

    Ophthalmic/Eye research techniques

  • Eyes and retinal tissues dissection in mice
  • Retinal tissue isolation and preparation, Lenses culture
  • Optical Coherence Tomography (OCT) Imaging
  • Refraction measurement using refractometry
  • Molecular biology and biochemistry

  • Nucleic acid techniques -preparation, purification, quantitation of DNA and RNA, PCR, qPCR), (Cell culture techniques including transfection), ELISA
  • Data Analysis and Communication

  • Data analysis and statistical interpretation
  • Computer proficiency including Microsoft Office Suite
  • Statistical software (SPSS, GraphPad, Matlab)
  • Figure preparation for publications and presentations
  • Scientific writing and manuscript preparation
  • Mentoring and training undergraduate/graduate students

Publications

· Khine YM, Taniguchi F, Nagira K, Nakamura K, Ohbayashi T,   Osaki M, Harada T. New insights into the efficacy of SR-16234, a selective   estrogen receptor modulator, on the growth of murine endometriosis-like   lesions. Am JReprod Immunol. 2018 Nov;80(5):e13023.

· Khine YM, Fuminori Taniguchi, and Tasuku Harada. Clinical   management of endometriosis-associated infertility. Reprod Med Biol. 2016 Feb   17;15(4):217-225.

· Harada T, Khine YM, Kaponis A, Nikellis T, Decavalas G,   Taniguchi F. The Impact of Adenomyosis on Women's Fertility. Obstet Gynecol   Surv. 2016 Sep;71(9):557-68.

· Azuma Y, Taniguchi F, Nakamura K, Nagira K, Khine YM, Kiyama T,   Uegaki T, Izawa M, Harada T. Lipopolysaccharide promotes the development of   murine endometriosis-like lesions via the nuclear factor-kappa B pathway. Am   J Reprod Immunol. 2017 Apr;77(4).

· Taniguchi F, Uegaki T, Nakamura K, Khine YM, Harada T,   Ohbayashi T, Harada T. Inhibition of IAP (inhibitor of apoptosis) proteins   represses inflammatory status via nuclear factor-kappa B pathway in murine   endometriosis lesions. Am J Reprod Immunol. 2018 Jan;79(1).

· Nagira K, Taniguchi F, Nakamura K, Tokita Y,   Tsuchiya N, Khine YM,  Harada T. Tokishakuyakusan, a Kampo medicine, attenuates endometriosis-like   lesions and hyperalgesia in murine with endometriosis-like symptoms. Am J   Reprod Immunol. 2019 Aug 24:e13182.

· Fuminori Taniguchi, Hermawan Wibisono, Khine YM, Tasuku Harada.   Animal models for research on endometriosis. Front Biosci (Ellite Ed). 2020   Jan 21:13;37-53.

· Courtney Linne, Khine Yin Mon, Shane   D’Souza, Heonuk Jeong, Xiaoyan Jiang, Dillon M Brown, Kevin Zhang 1,2, Shruti   Vemaraju, Kazuo Tsubota, Toshihide Kurihara, Machelle T Pardue, Richard A   Lang. Encephalopsin (OPN3) is required for normal refractive development and   the GO/GROW response to induced myopia. Mol Vis. 2023 May 14;29:39-57.

INTERNATIONAL PRESENTATION AND SCIENTIFIC MEETINGS

· Khine Yin Mon. New insights into the efficacy of SR-16234, a selective estrogen receptor modulator, on the growth of murine endometriosis-like lesions. (Oral presentation) (70th Annual Congress of the Japan Society of Obstetrics and Gynecology, Nagoya, Japan, 2019)

· Khine Yin Mon, Fuminori Taniguchi, Yukihiro Azuma, Tasuku Harada. New insights into the efficacy of SR-16234, a selective estrogen receptor modulator, on the growth of murine endometriosis-like lesions. (Poster) (The 7th Asian Congress on Endometriosis, Taipei) (2018)

· Khine Yin Mon, Fuminori Taniguchi, Yukihiro Azuma, Tasuku Harada. Treatment with a selective estrogen receptor modulator, SR-16234 results in regression of endometriosis-like lesions in a murine model. (Poster) (70 th Annual Congress of the Japan Society of Obstetrics and Gynecology, Sendai, Japan, 2018)

· Khine Yin Mon, Fuminori Taniguchi, Kei Nagira, Yukihiro Azuma, Masao Izawa, Tasuku Harada. SR-16234, a selective estrogen receptor modulator, represses development of endometriosis-like lesions in a murine model. (Oral presentation) (第39回日本エンドメトリオーシス学会学術講演会, Kyoto,Japan, 2018)

· Khine Yin Mon, Fuminori Taniguchi, Kei Nagira, Takashi Uegaki, Tasuku Harada. SR-16234, a selective estrogen receptor modulator, represses the development of endometriosis-like lesions in the murine model. (Poster) (69th Annual Congress of the Japan Society of Obstetrics and Gynecology, Hiroshima, Japan,2017)

· Khine Yin Mon, Fuminori Taniguchi, Kei Nagira, Takashi Uegaki, Tasuku Harada. SR-16234, a selective estrogen receptor modulator, represses development of endometriosis like lesions in murine model. (Oral presentation) (The 6th Asian Congress on Endometriosis, Iran)(2017)

· Khine Yin Mon, Fuminori Taniguchi, Akiko Enatsu, Ikuko Ota, Toshiko Toda, Tasuku Harada. Effects of low dose oral contraceptive pill containing drospirenone/ethinylestradiol in endometriosis patients with dysmenorrhea. (Poster) (The 5th Asian Congress on Endometriosis, Osaka, Japan) (2016)

· Khine Yin Mon. Role of Opn3 in the lens and refractive development (Oral Presentation) (Emory School of Medicine, United States) (2023)

Affiliations

  • MYANMAR MEDICAL ASSOCIATION (Member)
  • JAPAN SOCIETY OF OBSTETRIC AND GYNECOLOGY (Member)

Licensure

Medical License: Myanmar, Active since 2013

Languages

Japanese
Professional Working
English
Full Professional

Timeline

Postdoctoral Research Fellow

Department of Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati
03.2022 - Current

Assistant Professor

Department of Anatomy, Histochemistry and Cell Biology, Miyazaki University, Japan
01.2020 - 03.2020

Project Researcher

Department of Obstetric and Gynecology, Tottori University, Faculty of Medicine, Japan
06.2019 - 12.2019

Research Assistant/ Teaching Assistant

Department of Obstetric and Gynecology, Tottori University, Faculty of Medicine, Japan
04.2014 - 11.2018

Ph.D. -

Department of Obstetric And Gynecology, Tottori University, Faculty of Medicine

M.B.,B.S -

University of Medicine-2
KHINE YIN MON