Summary
Overview
Work History
Education
Skills
Websites
Personal Ongoing Bioinformatics projects
Certification
Professional webpage
Work Availability
Quote
Timeline
Generic

Lakshman Wadhwani

Iowa City,IA

Summary

Highly motivated, and newly minted computational biologist seeking a position as a Bioinformatics analyst/Bioinformatician in the life science/Healthcare industry, or Academia. Over ten years of multidisciplinary scientific work experience and an ability to self-start and adapt to the ever-evolving and intersecting fields of big data, biology and computer science.

Overview

16
16
years of professional experience
6
6

Certifications

Work History

QC Chemist

Cambrex Corp.
Charles City, IA
08.2022 - Current
  • Operated specialized scientific equipment and performed complex procedures to execute high-level analytical testing tasks.
  • Maintained analytical instrumentation and auxiliary laboratory equipment to maximize availability and functionality.
  • Monitored consumable laboratory supplies and replenished inventory to enable timely completion of testing activities.
  • Performed standard and proprietary physical testing and chemical analysis of raw chemical materials and finished products.
  • Prepared and standardized test equipment, test solutions and reagents to enable successful testing completion.
  • Generated technical reports and other documentation to record analytical test results and conclusions.

Analytical Chemist

Proctor & Gamble (Contractor- Apex systems)
Iowa City, IA
03.2018 - 04.2022
  • Conducted hundreds of weekly atomic absorption experiments for quantitative analysis of drugs and active ingredients in raw materials and final products (Shampoo and body wash)
  • Operated laboratory equipment and prepared compounds and solutions to conduct tests
  • Conducted dozens chemical tests daily (rheology, viscosity, specific gravity, laser diffraction,and spectrophotometry) to assist scientists in making qualitative and quantitative analyses of solid, liquid materials
  • Verify data integrity and accuracy
  • Performed various qualitative calculations to convert laboratory data into reportable forms
  • Calibrated and maintained laboratory testing equipment

Production Scientist/QC Analyst

Integrated DNA Technologies
Coralville, IA
07.2007 - 08.2016
  • Maintained compliance with safety and clean area procedures
  • Conducted hundreds of daily Mass spectrometry experiments (Electron spray Ionization, and MALDI-TOF) to measure mass-to-charge ratio of Ions confirming Oligonucleotide identity
  • Utilized RP-HPLC, Ion-Exchange HPLC, Single and multichannel capillary electrophoresis (CE) to measure purity of Oligonucleotides and presence of qPCR probe dyes and hydrophobic ligands
  • Performed data analysis and provided recommendations to improve upon current testing techniques
  • Conducted monthly internal audits and performed lab inspections every week

Education

Bachelor of Arts - Biology

Luther College
Decorah, IA

Graduate Course Work -

University of Iowa, Graduate College
Iowa City, IA
2017

Skills

  • Biology: Immunology, Oncology, Cancer Biology, Genomics, NGS, Molecular Biology, Genetics
  • Languages: Python, R, SQL, Bash, Shell scripting
  • Machine Learning: Linear regression, K-NN, Decision Trees, Logistic Regression, Neural networks, Dimensionality reduction, Clustering, Network analysis
  • Bioinformatics: GATK, HISAT2, samtools, bcftools, vcftools, Picard, BWA, VEP, ANNOVAR, Galaxy, IVG, COSMIC, UCSC Genome browser, scRNA, Seurat, IPA (Ingenuity Pathway Analysis)
  • Data Science: Apache Zeppelin & Jupyter Notebooks, Tableau, IBM Watson Studio, Numpy, Pandas, Matplotlib, data analysis, Conda, Git
  • Additional Competencies: Linux, HPC cloud computing & Scheduling(Sun-Grid Engine), LIMS, Github, AWS, IBM Watson Studio, JMP DOE (Design of Experiments)
  • Additional skills: Excellent written and verbal communication, Problem solving, Objectivity, Quick learner

Personal Ongoing Bioinformatics projects

Integrated variant analysis using Galaxy -Dec 2018

Replicated study using reproducible pipelines that create an integrated genomic profile of cancer and used the profile to find mutations associated with disease and potentially useful drugs.

Jeremy Goecks, et al. Open pipelines for integrated tumor genome profiles reveal differences between pancreatic cancer tumors and cell lines, Cancer Medicine, Volume 4, Issue 3, 2015, Pages 392-403, https://doi.org/10.1002/cam4.360

Pipelines and Data GitHub repository link ;

https://lakshmanwadhwani.github.io/Galaxy-Integrated-variant-analysis/

Analysis in R & Python of the Plasmodium Falciparum parasite 3D7 Mitochondrion genome- Sept 2019

link to GitHub repository;

https://Lakshmanwadhwani.github.io/PF3D7-analysis.wadhwani.github.io/

Neural network for breast cancer detection using Tensor flow in Google Colab - Oct 2019

link to the GitHub repository;

https://Lakshmanwadhwani.github.io/Breast-cancer-detection-neural-network/

Certification

IBM Data Science Professional Certificate

Professional webpage

· https://lakshmans-superb-project.webflow.io/

Work Availability

monday
tuesday
wednesday
thursday
friday
saturday
sunday
morning
afternoon
evening
swipe to browse

Quote

Science is what you know, philosophy is what you don’t know.
Betrand Russel

Timeline

QC Chemist

Cambrex Corp.
08.2022 - Current

Analytical Chemist

Proctor & Gamble (Contractor- Apex systems)
03.2018 - 04.2022

Production Scientist/QC Analyst

Integrated DNA Technologies
07.2007 - 08.2016

Bachelor of Arts - Biology

Luther College

Graduate Course Work -

University of Iowa, Graduate College

Similar Profiles

CREATE PROFILE
Lakshman Wadhwani