Lilibet Valdovinos
Summary
Experienced, result-driven professional with extensive technical animal care and laboratory experience. Demonstrated ability to excel in fast paced innovative environments, while developing leading-edge research products and cell-based therapies in early-stage biotech. Looking to obtain a challenging position in an organization that will effectively utilize my experience and offers opportunities for career development.
Overview
16
16
years of professional experience
1
1
Certification
Work History
Senior Research Associate
Shoreline Biosciences
10.2023 - 01.2025
- Executed multiple in vivo studies to support in vivo pharmacology tumor models to characterize efficacy of iNK-cell therapies and model development in hematological and solid tumor targets
- Proficient in tumor cell inoculation, tumor measurement by caliper, SQ/IP/IV injections, induction/maintenance of anesthesia, necropsy, and tissue harvest
- Performed IVIS imaging to measure local and systemic tumor burden
- Routinely performed dosing of mice through various routes
- Proficient in blood collection via cardiac puncture and submandibular vein
- Maintained accurate records and summarized data using Studylog, Benchling and GraphPad Prism
- Assisted in cell culture and maintenance for in vivo implant
Senior Research Associate I
Artiva Biotherapeutics
01.2023 - 09.2023
- Developed and executed multiple in vivo xenograft tumor models to characterize efficacy of candidate NK-cell therapies against novel hematological and solid tumor targets
- Proficient in tumor cell inoculation, tumor measurement by caliper, SQ/IP/IV injections, blood collection via RO, induction/maintenance of anesthesia, necropsy, and tissue harvest
- Performed IVIS imaging to measure local and systemic tumor burden
- Collected and processed blood samples to evaluate endpoints from in vivo studies via Meso Scale Discovery (MSD)
- Processed tumor and tissue samples using gentleMACS tissue dissociator for downstream analysis
- Routinely performed dosing of mice through various routes
- Proficient in terminal blood collection via cardiac puncture
- Maintained accurate records and summarized data using Excel, Benchling and GraphPad Prism
- Created in vivo SOP’s
- Responsible for cell culture and maintenance for in vitro assays and in vivo implant
Senior Research Associate
Onchilles Pharma
04.2022 - 01.2023
- Independently executed studies in mice in support of in vivo pharmacology projects, including tumor cell inoculation, tumor measurement by caliper, SQ/IP/IV injections, blood collection via RO or submandibular vein, induction/maintenance of anesthesia, necropsy, and tissue harvest
- Record in vivo study data in a timely and complete manner
- Responsible for coordinating vivarium operations, ordering appropriate supplies needed for studies, and ordering mice
- Assisted with blood and tissue processing
Research Associate II
Poseida Therapeutics
06.2020 - 04.2022
- Company Overview: Immuno-Oncology Department
- Execute studies in mice in support of in vivo pharmacology projects, including tumor cell inoculation, tumor measurement by caliper or BLI imaging, SQ/IP/IV injections, blood collection, induction/maintenance of anesthesia, and tissue harvest
- Organized detailed study records, performed data analysis, evaluated research in vivo studies, and presented results to the team
- Lead in vivo RA handling IND enabling studies
- Developed training strategies within the team to harmonize procedures
- Assisted with tumor tissue culture and tissue processing
- Immuno-Oncology Department
Research Associate II
BioDuro
01.2019 - 06.2020
- Company Overview: Oncology Department
- Accurately performed in vivo studies that included the following laboratory procedures: tumor measurements, dosing (PO, IP, IV, SQ, IM), blood collection, inoculation, tissue harvest, and processing
- Responsible for PDX tumor implanting and engraftment
- Responsible for recording in vivo study data in an accurate, timely and complete manner
- Responsible for coordinating vivarium operations, ordering appropriate supplies needed for studies, and ordering mice
- Provided training to personnel in proper animal laboratory procedures
- Ensured compliance with IACUC regulatory guidelines with animal care and welfare
- Established SOP process in Oncology department
- Responsible for creating, reformatting, and maintaining SOP’s
- Oncology Department
Laboratory Technician II
Charles River Laboratories
05.2015 - 12.2018
- Managed the San Diego site independently under minimal supervision from headquarters in Massachusetts
- Responsible for laboratory compliance prior to AAALAC, IACUC and USDA, inspections
- Assisted in providing leadership and motivation to all departmental personnel
- Responsible for training technicians across department
- Responsible for proficiency in all appropriate designated departmental SOP's with general knowledge of the lab processes
- Provided results and/or technical assistance to external customers via verbal and/or written communications
- Reconciled customer paperwork with submission documentation to ensure accuracy
- Responsible for the timely input of departmental results into laboratory data management system
- Euthanized and performed routine gross pathology and parasitology examinations of animals received from both internal and external customers
- Performed necropsies and tissue collections
- Collected samples and prepared tissues, bacterial, serologic, PCR, and histology samples
Animal Technician II
Charles River Laboratories
04.2014 - 05.2015
- Performed routine and moderately complex animal husbandry duties and monitored daily health and welfare to ensure quality of product
- Responsible for rodent breeding colonies consisting of multiple strains
- Properly documented work and observations performed
- Recording and reporting any findings in accordance with SOP’s
- Strictly followed all procedures necessary to maintain isolators
- Proper use of personal protective equipment
- Assisted in training new employees
Veterinary Technician
Aloha Animal Hospital
Vista, USA
09.2008 - 01.2014
- Followed standard operating procedures in the induction, intubation, monitoring, and assistance with surgical procedures
- Cared for hospitalized patients with oral medications, IV, IM, and SQ injections
- Calculated medication dosages based on animal weight and medical condition
- Placed and maintained IV catheters
- Treated animals in both routine and emergency situations
- Performed microscopic examination of blood, urine, ceruminous debris and fecal matter
- Obtained samples for laboratory procedures using sterile venipuncture and cystocentesis collection technique
- X-ray equipment knowledge
- Ran CBC and biochemistry profiles on blood analyzing laboratory equipment
- Sterilized surgery packs and operated autoclave
- Admitted patients, collecting and documenting detailed patient history
- Ensured record control, including documentation of all treatments, procedures, recommendations and communication in both digital and paper medical files
Skills
- Animal handling
- Dosing via various routes
- Tumor cell inoculation
- Collaborative skills
- Cross-functional skills
- Organizational skills
- Detail-oriented
- Written communication
- Verbal communication
- Teamwork
- Individual tasks
- Results-oriented mindset
- Hands-on experience evaluating CAR-T, iNK, and small molecules in in vivo oncology animal models
- Documentation skills
Education
- Palomar College, San Marcos, CA, 2007-2009
- Pima Medical Institute, Chula Vista, CA, 2004-2005
Certification
- ALAT Certification, 2018
Accomplishments
- Charles River Laboratory Customer Excellence Award, 2017
Languages
Spanish
Native/ Bilingual
Timeline
Senior Research Associate
Shoreline Biosciences
10.2023 - 01.2025
Senior Research Associate I
Artiva Biotherapeutics
01.2023 - 09.2023
Senior Research Associate
Onchilles Pharma
04.2022 - 01.2023
Research Associate II
Poseida Therapeutics
06.2020 - 04.2022
Research Associate II
BioDuro
01.2019 - 06.2020
Laboratory Technician II
Charles River Laboratories
05.2015 - 12.2018
Animal Technician II
Charles River Laboratories
04.2014 - 05.2015
Veterinary Technician
Aloha Animal Hospital
09.2008 - 01.2014
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