Summary
Overview
Work History
Education
Skills
Timeline
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LINH YEN DO

Boston,MA

Summary

Biochemistry graduate with hands-on experience in drug formulation and protein analysis, skilled in HPLC, SEC, and regulatory compliance. Experienced in research environments and collaborative projects, seeking to leverage my technical and analytical skills in drug development

Overview

3
3
years of professional experience

Work History

Intern

STC Biologics
Newton, USA
05.2024 - 08.2024
  • Analytical Techniques for Drug Development: Conducted protein purification using Size Exclusion Chromatography (SEC) and analyzed protein concentration with UV-Vis spectrophotometry, supporting drug formulation development by ensuring accurate molecular characterization.
  • Formulation Optimization: Prepared and optimized buffer solutions to maintain protein stability in drug formulations, contributing to the consistency and efficacy of protein-based therapeutics.
  • High-Performance Liquid Chromatography (HPLC): Performed HPLC to analyze protein samples, a key step in verifying the quality and purity of drug compounds.
  • Collaborative R&D: Assisted in experimental design, troubleshooting, and protocol development for protein characterization, applying problem-solving skills to streamline research processes and improve data reliability
  • Regulatory Compliance: Adhered to Good Laboratory Practice (GLP) standards in all laboratory activities, maintaining precise documentation for experimental processes in accordance with industry regulations.

Research Student

Suffolk University
Boston, USA
01.2022 - 05.2022
  • Conducted novel research on fumarase, a highly conserved Krebs cycle enzyme and tumor suppressor
  • Purified wild-type and variant fumarases via nickel affinity chromatography
  • Used site-directed mutagenesis to insert Lys230Arg mutation associated with fumarate hydratase deficiency in the gene encoding human recombinant His6-tagged fumarase
  • Purified and characterized wild-type and variant proteins, discovering that the fumarase variant is 5900-fold slower in vitro than in vivo compared to the wild-type enzyme

Research Student

Suffolk University
Boston, USA
01.2022 - 05.2022
  • Identified Francisella tularensis and suggested an appropriate therapeutic response (Tigecycline), illustrating skills in pathogen analysis and a foundational understanding of antimicrobial treatment options relevant to healthcare and hospital settings.

Education

Bachelor of Science - Biochemistry

Suffolk University
Boston, MA
05.2024

Skills

  • Technical Skills: SEC, HPLC, UV-Vis spectrophotometry, buffer formulation, site-directed mutagenesis, PCR, Western Blot, CRISPR-Cas9, DNA purification, plasmid preparation
  • Regulatory Compliance: GLP standards, documentation accuracy, protocol optimization
  • Data Analysis and Interpretation: Statistical analysis, enzyme kinetics, protein stability testing
  • Statistical Analysis: Ability to analyze experimental data using statistical methods to interpret results with precision

Timeline

Intern

STC Biologics
05.2024 - 08.2024

Research Student

Suffolk University
01.2022 - 05.2022

Research Student

Suffolk University
01.2022 - 05.2022

Bachelor of Science - Biochemistry

Suffolk University

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