Hi, I’m
Lois Howell Vuocolo
Louisville,CO
Overview
9
years of professional experience
3
Certificates
Work History
Prosoft Clinical12-1900
Senior Statistician
02.2022 - Current
Job overview
- Contributed to 25 FDA-submitted clinical trials.
- Assisted in drafting statistical analysis plans (SAPs) and table, listing, figures (TLF) mockups to aid data presentation for four phase 2 clinical trials.
- Programmed over 300 TLFs which passed validation and were submitted to the FDA, supporting data analysis in diverse medical research areas including psychiatric illnesses, Pharmacokinetics, label comprehension, and medical devices.
- Programmatically validated and quality control checked over 150 TLFs, analysis datasets, and ADaM datasets to ensure data integrity, resulting in FDA approval to continue from a phase 2 to phase 3 trial.
- Designed and implemented SAS programs for 40 CDISC compliant SDTM and ADaM domains across four studies, including validation and CDISC specifications. Adhered ADaM BDS and ADSL Implementation Guide v1.3, OCCDS Implementation Guide v1.1 standards, and SDTM Implementation Guide Version 3.4 compliance for all domains.
- Contributed to CRF annotation. Oversaw review process of Pinnacle 21 to maintain compliance standards. Coordinated efforts across statistics, sponsor, and data management teams to enhance project execution.
- Conducted thorough assessments and provided comments on case report forms (CRFs), protocols, and clinical study reports (CSRs) to support central nervous system (CNS), oncology, rheumatic disease research, and label comprehension studies.
- Performed comprehensive categorical and continuous outcomes analysis to derive insights, employing chi-square tests, Fisher's exact test, logistic regression, ANOVA, ANCOVA, and t-tests.
- Developed and implemented longitudinal models, including mixed effects models, to analyze complex data sets and inform decision-making processes.
- Analyzed and produced data visualization for complex survival data to identify trends and enhance predictive modeling capabilities.
- Ensured compliance with International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use Good Clinical Practice (ICH GCP) standards.
West Chester University Office of SustainabilityWest Chester, PA
Data Analyst
09.2021 - 04.2022
Job overview
- Collaborated with Director Bradley Flamm, PhD, to conduct research and facilitate sustainability projects.
- Achieved a top-tier STARS Platinum rating from AASHE in 2022, a significant sustainability recognition, for university sustainability reporting.
- Identified trends in sustainability data to drive improvements in waste reduction programs and optimize resource management.
- Assisted in gathering data from multiple offices through surveys to evaluate university sustainability initiatives. Supported teams in analyzing the effectiveness of existing programs.
Stroud Water Research CenterAvondale, PA
Data Analyst
05.2021 - 03.2022
Job overview
- Collaborated with Dr. Charles Dow, PhD, to analyze hundreds of data sets and derive insights for over five ongoing research projects.
- Applied R to transform hundreds of raw data files into a structured format, enhancing accessibility for further analysis.
- Assisted in developing predictive models (random forest, KNN, decision trees) using R to support data analysis initiatives. Collaborated with team members to enhance model accuracy and efficiency. Contributed to the preparation of reports detailing model outcomes and insights.
- Applied advanced statistical techniques, such as multivariate regression, ANOVA, and logistic regression, to drive insights for ongoing water research projects within the center.
Goldman Sachs – Finance DivisionSalt Lake City, UT
Senior Financial Analyst
12.2019 - 12.2020
Job overview
- Worked with Private Wealth Management to create and manage over 1,000 hybrid fixed income strategies, crossover high yield and investment grade strategies, and Environmental, Social, Governance strategies as well as standard taxable fixed income.
- Published monthly reporting metrics on the above strategies.
Goldman Sachs – Finance DivisionSalt Lake City, UT
Financial Analyst
07.2018 - 11.2019
Job overview
- Analyzed different performance metrics for thousands of separate accounts and institutional portfolios within the Investment Management Division for Quantitative Investment Strategies (QIS) and Master Limited Partnerships (MLP).
- Prepared detailed reports on market trends, providing insights for strategic planning and decision-making.
Goldman Sachs – Finance DivisionSalt Lake City, UT
Summer Analyst
06.2017 - 08.2017
Job overview
- Independently created and presented on Robo Advisor disruption and growth.
- Worked with a group of summer interns to analyze and present on the benefits of different accounting treatments.
Education
West Chester University of PennsylvaniaWest Chester, PA
Master of Science from Applied Statistics
08.2022
University Overview
University of Southern CaliforniaLos Angeles, CA
Bachelor of Arts from Economics
05.2018
University Overview
Skills
- Drafting CSRs
- Data visualization expertise
- Skilled in complex SAS data analysis
- Machine learning techniques
- Skilled in applying survival analysis methods
- Longitudinal data analysis
- Experience in multi-phase (1-3) clinical trials
- Bayesian statistics
Timeline
Senior Statistician
Prosoft Clinical
02.2022 - Current
Data Analyst
West Chester University Office of Sustainability
09.2021 - 04.2022
Data Analyst
Stroud Water Research Center
05.2021 - 03.2022
Senior Financial Analyst
Goldman Sachs – Finance Division
12.2019 - 12.2020
Financial Analyst
Goldman Sachs – Finance Division
07.2018 - 11.2019
Summer Analyst
Goldman Sachs – Finance Division
06.2017 - 08.2017
West Chester University of Pennsylvania
Master of Science from Applied Statistics
University of Southern California
Bachelor of Arts from Economics
Certification
- Good Clinical Practices (GCP) - 2022-Present
- General Data Protection Regulation (GDPR) - 2022-Present
- Yoga Teaching Certification, 200 hour - 2024-Present
ACTIVITIES
ACTIVITIES
- Participant, Philadelphia Women’s Triathlon 2024, The Iron Bruin, UCLA Triathlon 2016
- Member, USC Women in Economics 2020-2021
- Member, USC Economic Leadership Council 2020-2021
- Grant Recipient, HSBC Scholars 2016-2018
- Additional Activities – Trail running, hiking, fine art (acrylic painting, drawing)