Mame Basse

Research Interests

• Molecular mechanism of carcinogenesis
• The regulation of signaling pathways in carcinogenesis
• Post-translational modification of tumor suppressors and oncoproteins
• Small molecule therapeutics for cancer treatment
• Drugs Discovery and Development

• Certificate in Molecular Biology: DNA Replication and Repair, Massachusetts Institute of Technology (MIT), MA, 01/01/2015
• Certificate in Medicinal Chemistry, Davidson College, Davidson, NC, 01/01/2014
• Certificate of Specialization (CES) in Quality Control of Food and Medicine, University Cheikh Anta Diop (UCAD), Dakar, Senegal, 01/01/2007
• Postgraduate certificate in Immunology, University Cheikh Anta Diop (UCAD), Dakar, Senegal, 01/01/2007
• Postgraduate certificate in Parasitology, University Cheikh Anta Diop (UCAD), Dakar, Senegal, 01/01/2006
• Postgraduate certificate in Bacteriology, University Cheikh Anta Diop (UCAD), Dakar, Senegal, 01/01/2005
• Postgraduate certificate in Molecular Biology, University Cheikh Anta Diop (UCAD), Dakar, Senegal, 01/01/2005

• Ph.D. Chinese Government Scholarship Council for Research Excellences Awards, Chinese Government, 01/01/2007
• Master Program: Government of Senegal Research Grant Awards, Government of Senegal, 01/01/2003

• Jade-1 as a Target of pVHL in Renal Cancer, Delia Lopez, Ruoyu Tian, Mame B. Basse, Deepthi Desai, Neil Lajkiewicz, Lauren E. Brown, John A. Porco, Herbert T. Cohen, 12th International VHL Medical Symposium, MGH, 04/07/2016
• Small molecule therapeutics to increase Jade-1 protein abundance in kidney cancer, Basse MB, Mittal A, Lopez D, Tian R, Desai D, Lajkiewicz N, Brown LE, Porco JA, Cohen HT, New England Sciences Symposium, Harvard Medical School, 04/03/2016
• The role of Jade-1 in DNA Mismatch Damage and Repair in Renal Cancer, Ruoyu Tian, Delia Lopez, Deepthi Desai, Mame B. Basse, Rachel L. Flynn, Herbert T.Cohen
• Potentiation of Apoptin-induced-apoptosis by Cecropin B-like Antibacterial Peptide ABPs1 in Human HeLa Cervical Cancer Cell Lines is associated with Membrane Pores formation and Caspase-3 Activation, Basse MB, Wang Jigui, Yu Fuxian, Sun Jiazeng, Zhili Li, Weiquan Liu
• J. Microbiol. Biotechnol., 24(6), 756–764, 2014
• MicroRNA profile analysis of a feline kidney cell line before and after infection with mink enteritis virus, Jiazeng Sun, Jigui Wang, Shuang Wang, Daoli Yuan, Basse MB, Zhili Li, Bao Yi, Weiquan Liu, Gene, 539(2), 224-229, 2014
• Co-expression of apoptin (VP3) a Chicken Anemia Virus gene and ABPS1 an Antibacterial Peptide cecropin B mutant gene, induce higher rate of apoptosis in HepG2 and A375 cell lines, Basse MB, Wang Jigui, Yu Fuxian, Wang Shuang, Yuan Daoli, Sun Jiazeng, Zhili Li, Bao Yi, Weiquan Liu
• Afr. J. Biotechnol., 11(49), 10981-10988, 2012
• Comparative study of Plate Count Agar (PCA) and Marine Agar (MA) media, used for the search for the Total Mesophile and Aerobic Microorganisms in frozen sole fillets, Basse MB, Sylla K. S. B., Musabyemariya B., Seydi Mg.
• J. of Microb. & Hyg. Alim., 19(55), 76-81, 2007